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Evaluation of imaging protocol for ECT based on CS image reconstruction algorithm

Chinese Physics C 2014年第4期38卷 111-116页

作者：周小林贠明凯曹学香刘双全王璐黄先超魏龙 Key Laboratory of Nuclear Analytical Techniques Institute of High Energy PhysicsChinese Academy of Sciences Beijing Engineering Research Center of Radiographic Techniques and Equipment University of Chinese Academy of Sciences

Single-photon emission computerized tomography and positron emission tomography are essential med- ical imaging tools, for which the sampling angle number and scan time should be carefully chosen to give a good compromise between image quality and radiopharmaceutical dose. In this study, the image quality of different ac- quisition protocols was evaluated via varied angle number and count number per angle with Monte Carlo simulation data. It was shown that, when similar imaging counts were used, the factor of acquisition counts was more important than that of the sampling number in emission computerized tomography. To further reduce the activity requirement and the scan duration, an iterative image reconstruction algorithm for limited-view and low-dose tomography based on compressed sensing theory has been developed. The total variation regulation was added to the reconstruction process to improve the signal to noise Ratio and reduce artifacts caused by the limited angle sampling. Maximization of the maximum likelihood of the estimated image and the measured data and minimization of the total variation of the image are alternatively implemented. By using this advanced algorithm, the reconstruction process is able to achieve image quality matching or exceed that of normal scans with only half of the injection radiopharmaceutical dose.

关键词： ECT imaging protocol compressed sensing total variation

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