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Xenon-enhanced CT assessment of cerebral blood flow in stroke-in-progress patients with unilateral internal carotid artery or middle cerebral artery stenosis

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Neuroscience Bulletin 2013年第6期29卷 693-700页

作者： Zhen-Ni Guo Ge Yang Hong-Wei Zhou Jing Wang Jiang Wu Yi Yang Department of Neurology the First Norman Bethune Hospital of Jilin University Department of Geriatric Medicine the Affiliated Hospital of Changchun University of Chinese Medicine Department of Radiology the First Norman Bethune Hospital of Jilin University

Carotid or cerebral artery stenosis resulting in low perfusion is a major cause of ischemic *** the unique hemodynamic features in each patient undergoing a stroke-in-progress（SIP） and the correlation between progression and cerebral blood flow（CBF） status would help in the diagnosis and treatment of individual *** used xenonenhanced CT（Xe-CT） to examine cerebral perfusion in patients with or without SIP（30 patients/group）,recruited from October 2009 to October *** SIP patients with unilateral stenosis in the internal or middle cerebral artery were *** occurrence of watershed infarction was higher in the SIP group than in the non-SIP group（P ＆lt;0.05）.In the SIP group,larger hypoperfused areas were found around the lesions than in the non-SIP *** the SIP group,the CBF values in the ipsilateral areas were significantly lower than those in corresponding regions on the contralateral *** values in the contralateral hemisphere were significantly lower in the SIP group than in the non-SIP *** SIP patients,infarctions were surrounded by larger hypoperfused areas than in non-SIP *** larger hypoperfused areas may result in pathological damage to the brain that is responsible for the progression of stroke.

关键词： cerebral blood flow stroke in progress artery stenosis xenon-enhanced CT hypoperfusion

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