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Oral administration of hyperoxygenated solution for the prophylaxis of gastric ulceration induced by stress or Helicobacter pylori

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医学争鸣 2015年第6期6卷 28-34页

作者： MA Hong-Wei WU Ya-Qiong ZHANG Hai-Feng Experiment Teaching Center School of Basic Medicine Fourth Military Medical University School of Life Sciences Shaanxi Normal University

Oxygen was first discovered by Sweden chemist Scheele in 1773 and convinced as an essential factor for living by French scientists in *** tackle with different hypoxic emergencies,corresponding medical approaches,*** or nasal catheter oxygen inhalation,breathing machine,hyperbaric oxygen therapy etc.,have been contrived in ***,one mortal trouble exists in all these conventional ways,*** must rely on the ventilation and gas exchange via lungs,thus not being able to promptly render oxygen to specific hypoxia *** solution(HOS),a new kind of medical liquid which can be orally taken or intravenously administrated,has been widely applied as an auxiliary method of offering oxygen in China.A large number of experiments have proved its validity in the treatment of myocardial and cerebral ischemia/reperfusion injury,nerve lesions,shock,respiratory diseases,neonatal hypoxia and so *** findings suggest that HOS might not only play a role of increasing oxygen pressure in local region,but also conspicuously contribute to improving the pathologic process of hypoxia,which coincidently is the vital link in stress-induced lesions in the gastrointestinal ***,Helicobacter pylori(***),a kind of microaerophilic(anaerobic)bacterium which can hardly survive in an aerobic atmosphere,has also been identified as an independent risk factor for the occurrence and development of *** the etiology of peptic ulceration and the features of HOS,we hypothesize that drinking HOS might prevent gastric ulceration caused by stress or anaerobic ***.

关键词： hyperoxygenated solution gastric ulceration prophylaxis stress Helicobacter pylori

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