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Transurethral seminal vesiculoscopy in the diagnosis and treatment of persistent or recurrent hemospermia： a single- institution experience

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Asian Journal of Andrology 2009年第5期11卷 566-570,I0002页

作者： Zhi-Yong Liu Ying-Hao Sun Chuan-Liang Xu Jian-Guo Hou Xu Gao Xin Lu Hua-Mao Ye Lin-Hui Wang Xiao-Feng Gao Shanghai Changhai Hospital the Second Military Medical University Shanghai 200433 China

The diagnosis and treatment of hemospermia presents significant difficulty, especially if it persists or recurs. In this retrospective study, we assessed whether transurethral seminal vesiculoscopy is feasible and effective in the diagnosis and treatment of hemospermia. To address this complex condition, we report our experience in a population of patients treated with transurethral seminal vesiculoscopy. From February 2006 to July 2008, 72 hemospermic patients underwent transurethral seminal vesiculoscopy examination and treatment at our urology center. Transurethral seminal vesiculoscopy was performed by a 7-F or 8-F rigid ureteroscope. The endoscopic procedure was conducted through the normal anatomic route of the seminal tracts. In this series, the mean follow-up period was 21.7 months. Definite diagnosis was made for 93.1% patients, and 94.4% patients were cured or showed a decrease in their symptoms. Postoperative complications were not observed in the study. Our study proves that transurethral seminal vesiculoscopy is effective in the diagnosis and treatment of hemospermia with minimal complication.

关键词： diagnosis hemospermia transurethral seminal vesiculoscopy treatment

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Transurethral seminal vesiculoscopy for recurrent hemospermia： experience from 419 cases

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Asian Journal of Andrology 2018年第5期20卷 438-441页

作者： Rui Chen Lei Wang Xia Sheng Shu-Guang Piao Xin-Wen Nian Xin Cheng Tie Zhou Hui-Zhen Li Ya-Wei Liu Guang-Hua Chen Chun-Lei Zhang De-Pei Kong Guang-An Xiao Xin Lu Zhen-Yu Jia Zhi-Yong Liu Ying-Hao Sun Department of Urology Shanghai Changhai Hospital Second Military Medical University Shanghai 200433 China Medical College of Chinese People's Liberation Army and Chinese People's Liberation Army General Hospital Beijing 100853 China

We summarized our experience in transurethral seminal vesiculoscopy （TSV） for recurrent hemospermia by introducing surgical techniques, intraoperative findings, and treatment outcomes. TSV was performed in 419 patients with an initial diagnosis of persistent hemospermia at Shanghai Changhai Hospital （Shanghai, China） from May 2007 to November 2015. TSV was successfully performed in 381 cases （90.9%）. hemospermia was alleviated or disappeared in 324 （85.0%） patients by 3 months after surgery. Common intraoperative manifestations were bleeding, obstruction or stenosis, mucosal lesions, and calculus. Endoscopic presentation of the ejaculatory duct orifice and the verumontanum was categorized into four types, including 8 （1.9%）, 32 （7.6%）, 341 （81.4%）, and 38 （9.1%） cases in Types A, B, C, and D, respectively. TSV is an effective and safe procedure in the management of seminal tract disorders. This study may help other surgeons to become familiar with and improve this procedure. However, further multicentric clinical trials are warranted to validate these findings.

关键词： endoscopy hemospermia transurethral seminal vesiculoscopy

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hemospermia is not associated with the production of antisperm antibody

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Journal of Reproduction and Contraception 2015年第4期26卷 223-228页

作者： Yue-juan ZHANG Rui HUANG Dong CHEN Bao-guo XIE Wei-jie ZHU Department of New Medicine the First Affiliated Hospital Jinan University Institute of Reproductive Immunology College of Life Science and Technology Jinan University

Objective To investigate whether hemospermia is involved in the production of antisperm antibodies （ASA）. Methods A total of 40 males with hemospermia were enrolled in this study. These males were divided into 3 groups according to their fertile status： 18 cases were patients who visited the infertility clinic （group A）, 8 had fertility （group B）, and 14 did not know their fertile status （group C）. Semen samples were collected and ASA levels were detected by the direct immunobead test （D-IBT）. Leukocytes in semen were assessed by the peroxi- dase assay. Results None of these males with hemospermia were found to display significant levels of ASA in the 3 groups. The number of cases who had increased levels of leukocytes in the semen samples of groups A, B and C were 15 （83.3%）, 6 （75.0%） and 12 （85.7%）, respectively. Conclusion hemospermia is not associated with the production of ASA. It is worth noting that the leukocyte levels are increased in semen of males with hemospermia.

关键词： hemospermia antisperm antibody (ASA) infertility leukocyte

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Transurethral seminal vesiculoscopy in the diagnosis and treatment of seminal vesicle stones

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Chinese Medical Journal 2012年第8期125卷 1475-1478页

作者： SONG Tao ZHANG Xu ZHANG Lei ZHANG Fan FU Wei-jun Department of Urology Clinical Division of SurgeryChinese People's Liberation Army General HospitalBeijing 100853China

Background Seminal vesicle stones are one of the main causes of persistent hemospermia. Treatment requires removal of the stone, generally through open vesiculectomy. The purpose of this study was to apply a transurethral seminal vesiculoscopy for diagnosis and treatment of the seminal vesicle stones with an ureteroscope. We assessed whether this transurethral endoscopic technique is feasible and effective in the diagnosis and treatment of the seminal vesicle stones with intractable hemospermia. Methods Totally 12 patients with intractable hemospermia underwent transurethral seminal vesiculoscopy through the distal seminal tracts using a 7.3-French rigid ureteroscope. Age of patients ranged from 25 to 57 years （mean age （43.7±10.5） years）. The patients＇ symptoms ranged in duration from 4 to 180 months （mean duration （47.8±45.3） months）. All patients underwent transrectal ultrasonography, pelvic computed tomography or magnetic resonance imaging before the operation. Positive imaging findings were observed in patients with seminal vesicle stones and dilated seminal vesicle size. A 7.3-French rigid ureteroscope entered the lumen of the verumontanum, and then the seminal vesicle under direct vision. Seminal vesicle stones were found unilaterally in 11 cases and bilaterally in one case. Results All 12 patients successfully underwent transurethral seminal vesiculoscopy. The seminal vesicle interior with single or multiple yellowish stones ranging from 1 to 5 mm in diameter was clearly visible. All the stones were easily fragmented and endoscopically removed using a grasper. The operative time was 30 to 120 minutes （mean （49±22） minutes）. The mean follow-up period was （6.9±3.0） months （range 3-13 months）. Symptoms of hemospermia disappeared after one month in 10 patients and after three months in two patients. Three patients with painful ejaculation could completely be relieved postoperation. There was also improvement in one patient with erectile dysfunction. There were n

关键词： seminal vesicle stones hemospermia transurethral seminal vesiculoscopy ureteroscope

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