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Detection and Classification of hemorrhages in Retinal Images

Computer Systems Science & Engineering 2023年第2期44卷 1601-1616页

作者： Ghassan Ahmed Ali Thamer Mitib Ahmad Al Sariera Muhammad Akram Adel Sulaiman Fekry Olayah College of Computer Science and Information Systems Najran UniversityNajran61441Saudi Arabia Department of Studies in Computer Science University of MysoreMysoreIndia

Damage of the blood vessels in retina due to diabetes is called diabetic retinopathy(DR).hemorrhages is theﬁrst clinically visible symptoms of *** paper presents a new technique to extract and classify the hemorrhages in fundus *** normal objects such as blood vessels,fovea and optic disc inside retinal images are masked to distinguish them from *** masking blood vessels,thresholding that separates blood vessels and background intensity followed by a newﬁlter to extract the border of vessels based on orienta-tions of vessels are *** masking optic disc,the image is divided into sub-images then the brightest window with maximum variance in intensity is *** the candidate dark regions are extracted based on adaptive thresholding and top-hat morphological *** are extracted from each candidate region based on ophthalmologist selection such as color and size and pattern recognition techniques such as texture and wavelet *** different types of Support Vector Machine(SVM),Linear SVM,Quadratic SVM and Cubic SVM classiﬁer are applied to classify the candidate dark regions as either hemor-rhages or *** efﬁcacy of the proposed method is demonstrated using the standard benchmark DIARETDB1 database and by comparing the results with methods in *** performance of the method is measured based on average sensitivity,speciﬁcity,F-score and *** results show the Linear SVM classiﬁer gives better results than Cubic SVM and Quadratic SVM with respect to sensitivity and accuracy and with respect to speciﬁcity Quadratic SVM gives better result as compared to other SVMs.

关键词： Diabetic retinopathy hemorrhages adaptive thresholding support vector machine

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Intracranial pressure monitoring:Gold standard and recent innovations

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World Journal of Clinical Cases 2019年第13期7卷 1535-1553页

作者： Deb Sanjay Nag Seelora Sahu Amlan Swain Shashi Kant Department of Anaesthesiology and Critical Care Tata Main Hospital

Intracranial pressure monitoring (ICP) is based on the doctrine proposed by Monroe and Kellie centuries ago. With the advancement of technology and science, various invasive and non-invasive modalities of monitoring ICP continue to be developed. An ideal monitor to track ICP should be easy to use, accurate, reliable, reproducible, inexpensive and should not be associated with infection or haemorrhagic complications. Although the transducers connected to the extra ventricular drainage continue to be Gold Standard, its association with the likelihood of infection and haemorrhage have led to the search for alternate noninvasive methods of monitoring ICP. While Camino transducers, Strain gauge micro transducer based ICP monitoring devices and the Spiegelberg ICP monitor are the emerging technology in invasive ICP monitoring, optic nerve sheath diameter measurement, venous opthalmodynamometry, tympanic membrane displacement, tissue resonance analysis, tonometry, acoustoelasticity, distortionproduct oto-acoustic emissions, trans cranial doppler, electro encephalogram, near infra-red spectroscopy, pupillometry, anterior fontanelle pressure monitoring, skull elasticity, jugular bulb monitoring, visual evoked response and radiological based assessment of ICP are the non-invasive methods which are assessed against the gold standard.

关键词： Intracranial pressure increase Craniocerebral trauma Subarachnoid hemorrhages

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Evolution of endovascular mechanical thrombectomy for acute ischemic stroke

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World Journal of Clinical Cases 2014年第11期2卷 614-622页

作者： Colin J Przybylowski Dale Ding Robert M Starke Christopher R Durst R Webster Crowley Kenneth C Liu Department of Neurological Surgery University of VirginiaCharlottesvilleVA 22908United States Department of Radiology and Medical Imaging University of Virginia Charlottesville VA 22908 United States

Acute ischemic stroke(AIS) is a common medical problem associated with significant morbidity and mortality worldwide. A small proportion of AIS patients meet eligibility criteria for intravenous thrombolysis(IVT) with recombinant tissue plasminogen activator, and its efficacy for large vessel occlusion is poor. Therefore, an increasing number of patients with AIS are being treated with endovascular mechanical thrombectomy when IVT is ineffective or contraindicated. Rapid advancement in catheter-based and endovascular device technology has led to significant improvements in rates of cerebral reperfusion with these devices. Stentrievers and modern aspiration catheters have now surpassed earlier generation devices in the degree and rapidity of revascularization. This progress has been achieved with no concurrent increase in risk of major complications or mortality, both when used alone or in combination with IVT. The initial randomized controlled trials comparing endovascular therapy to IVT for AIS failed to show superior outcomes with endovascular treatment, butkey limitations of each trial may limit the significance of these results to current practice. While endovascular devices and operator experience continue to evolve, we are optimistic that this will be accompanied by improvements in patient outcomes. This review highlights the major endovascular devices used in current practice and the trials which have investigated their efficacy.

关键词： Cerebral infarction Endovascular procedures Intracranial hemorrhages Stents Stroke

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