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Irradiation methods and nozzle design for the advanced proton therapy facility

Chinese Physics C 2010年第4期34卷 516-520页

作者：舒航方守贤关遐令唐靖宇刘德康傅世年李刚刘力陈沅焦毅邱静 Institute of High Energy Physics CAS

A conception design of the Advanced Proton therapy Facility （APTF） has been carried out. The system intentionally employs a slow-cycling synchrotron with a maximum energy of 250 MeV, two rotating gantries and two fixed beam nozzles for the treatment. In this paper, we try to compare the strength and weaknesses between the two treatment methods： the beam spreading and the pencil beam scanning. The application of the pencil beam scanning method and the double-scattering method together with the related nozzle design at APTF is also given. The simulation results of employing the double-scattering method have been given during the preliminary design.

关键词： hadron therapy irradiation method nozzle pencil scanning spreading system gantry

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ATPF–a dedicated proton therapy facility

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Chinese Physics C 2010年第3期34卷 383-388页

作者：方守贤关遐令唐靖宇陈沅邓昌东董海义傅世年焦毅舒航欧阳华甫邱静石才土孙虹韦杰杨梅张旌 Institute of High Energy Physics CAS

A proton therapy facility based on a linac injector and a slow-cycling synchrotron is proposed. To obtain good treatments for different cancer types, both the spot scanning method and the double-scattering method are adopted in the facility, whereas the nozzles include both gantry and fixed beam types. The proton accelerator chain includes a synchrotron of 250 MeV in maximum energy, an injector of 7 MeV consisting of an RFQ and a DTL linac, with a repetition rate of 0.5 Hz. The slow extraction using the third-order resonance and together with the RFKO method is considered to be a good method to obtain a stable and more-or-less homogenous beam spill. To benefit the spot scanning 200 between 60 MeV and 230 MeV. A new method method, the extraction energy can be as many as about - the emittance balancing technique of using a solenoid or a quadrupole rotator is proposed to solve the problem of unequal emittance in the two transverse planes with a beam slowly extracted from a synchrotron. The facility has been designed to keep the potential to be upgraded to include the carbon therapy in the future.

关键词： hadron therapy irradiation method slow extraction emittance balancing gantry

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A simulation study of a dual-plate in-room PET system for dose verification in carbon ion therapy

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Chinese Physics C 2014年第8期38卷 116-121页

作者：陈泽胡正国陈金达张秀玲郭忠言肖国青孙志宇黄文学王建松 Institute of Modern Physics Chinese Academy of Sciences University of Chinese Academy of Sciences

During carbon ion therapy, lots of positron emitters such as 11C, 15O, 11C are generated in irradiated tissues by nuclear reactions, and can be used to track the carbon beam in the tissue by a positron emission tomography （PET） scanner. In this study, an dual-plate in-room PET scanner has been designed and evaluated based on the GATE simulation platform to monitor patient dose in carbon ion therapy. The dual-plate PET is designed to avoid interference with the carbon beamline and with patient positioning. Its performance was compared with that of four-head and full-ring PET scanners. The dual-plate, four-head and full-ring PET scanners consisted of 30, 60, 60 detector modules, respectively, with a 36 cm distance measurements. Each detector module consisted of a between directly opposite detector modules for dose deposition 24~24 array of 2 mm×2 mm×18 mm LYSO pixels coupled to a Hamamatsu H8500 PMT. To estimate the production yield of positron emitters, a 10 cm×15 cm×15 cm cuboid PMMA phantom was irradiated with 172, 200, 250 MeV/u 12C beams. 3D images of the activity distribution measured by the three types of scanner are produced by an iterative reconstruction algorithm. By comparing the longitudinal profile of positron emitters along the carbon beam path, it is indicated that use of the dual-plate PET scanner is feasible for monitoring the dose distribution in carbon ion therapy.

关键词： hadron therapy PET GATE simulation

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