检索结果-南通市图书馆

Bio-modulation of scaring glaucoma Filtration Surgery using a novel application of coated magnesium

Journal of Magnesium and Alloys 2021年第3期9卷 883-894页

作者： Xiangji Li Richard Filek Xiaomin Zhu Huanhuan Gao Liying Qiao Hong Liu Lin Xie Yong Wang Fusheng Pan Cindy ML Hutnik Department of Ophthalmology Institute of Surgery ResearchDaping HospitalArmy Medical UniversityChongqing 400042China Department of Ophthalmology Western UniversityIvey Eye InstituteSt.Joseph's Health Care LondonLondonONCanada Department of Ophthalmology The Third Affiliated HospitalChongqing Medical UniversityChongqing 400016China Collage of Material Science&Engineering Chongqing UniversityChongqing 400045China National Engineering Research Center for Magnesium Alloys Chongqing UniversityChongqing 400045China

Filtration surgery still plays a mainstream role of treatment for *** scarring is the main cause of surgical *** study evaluated the biocompatibility and anti-proliferative properties of pure magnesium with three different coatings,which are hydroxyapatite(HA),dicalcium phosphate dihydrate(DCPD)and DCPD+stearic acid(SA),in a primary culture of human tenon's capsule fibroblasts(HTCFs)and in rabbit glaucoma Filtration *** and glass were used as controls in vitro,and trabeculectomy was used as control in *** results show the number and shape of HTCFs seeded on different coatings showed less quantity and poor cell *** type of coated magnesium demonstrated significantly decreased metabolic activity of ***+SA showed higher cytotoxicity than the other *** inhibition of proliferation was observed with the DCPD+SA *** expression ofα-SMA was decreased in the cells when seeded on all of the coated magnesium *** vivo,no obvious adverse effects were observed after *** significant difference existed for any of the different samples regarding different ion concentrations in the aqueous *** inflammatory response in the titanium,DCPD and DCPD+SA treated eyes was more intense than in the trabeculectomy alone and HA *** Blot analysis showed that collagen-1 andα-SMA expression was significantly lower in the titanium,HA,DCPD and DCPD+SA groups compared with the *** coatings on magnesium were able to affect the corrosive properties,which in turn,influenced the morphology and function of *** coated magnesium may be considered a very promising biodegradable material for the next generation of glaucoma drainage devices.

关键词： glaucoma glaucoma drainage device Fibrosis Tenon's capsule fibroblasts Magnesium Coating

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Combined pars plana vitrectomy and Baerveldt glaucoma implant placement for refractory glaucoma

引用

International Journal of Ophthalmology(English edition) 2015年第5期8卷 916-921页

作者： Thalmon R.Campagnoli Sung Soo Kim William E.Smiddy Steve J.Gedde Donald L.Budenz Richard K.Parrish II Paul F.Palmberg William Feuer Wei Shi Department of Ophthalmology Bascom Palmer Eye InstituteUniversity of Miami Miller School of Medicine Department of Ophthalmology Gangnam Severance HospitalYonsei University College of Medicine Department of Ophthalmology University of North Carolina

AIMTo evaluate outcomes of combined pars plana vitrectomy and Baerveldt glaucoma implant (PPV-BGI) placement for refractory *** medical records of 92 eyes (89 patients) that underwent PPV-BGI were retrospectively reviewed, including 43 eyes with neovascular glaucoma (NVG) and 49 eyes with other types of glaucoma (non-NVG).RESULTSOutcome measures were visual acuity (VA), intraocular pressure (IOP), glaucoma medical therapy, complications, and success [VA>hand motions (HM), IOP≥6 mm Hg and ≤21 mm Hg, no subsequent glaucoma surgery]. Cumulative success rates for the non-NVG group and NVG group were 79% and 40% at 1y, respectively (P=0.038). No difference in the rates of surgical success were found between pars plana and anterior chamber tube placement. Preoperative IOP (mean±SD) was 30.3±11.7 mm Hg in the Non-NVG group and 40.0±10.6 mm Hg in the NVG group, and IOP was reduced to 15±9.5 mm Hg in the non-NVG group and 15±10.5 mm Hg in the NVG at 1y. Number of glaucoma medications (mean±SD) decreased from 2.7±1.3 in the non-NVG group and 2.8±1.3 in the NVG group preoperatively to 0.76±1.18 in the non-NVG group and 0.51±1.00 in the NVG group at 1y. Improvement in VA of ≥2 Snellen lines was observed in 25 (27%) eyes, although only 33% of non-NVG eyes and 2.3% of NVG eyes maintained VA better than 20/200 at 1y. Nonclearing vitreous hemorrhage was the most common postoperative complication occurring in 16 (17%) eyes, and postoperative suprachoroidal hemorrhages developed in 5 (5.4%) ***-BGI is a viable surgical option for eyes with refractory glaucoma, but visual outcomes are frequently poor because of ocular comorbidities, especially in eyes with NVG. The location of tube placement does not influence surgical outcome and should be left to the discretion of the surgeon.

关键词： glaucoma drainage device pars plana vitrectomy refractory glaucoma neovascular glaucoma

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：