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检索条件"主题词=gene promoter."
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Enhancement of human ACAT1 gene expression to promote the macrophage-derived foam cell formation by dexamethasone
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Cell Research 2004年 第4期14卷 315-323页
作者: Li YANG, Jin Bo YANG, Jia CHEN, Guang Yao YU, Pei ZHOU, Lei LEI, Zhen Zhen WANG, Catherine CY CHANG, XinYing YANG, Ta Yuan CHANG, Bo Liang LI State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, 320 Yueyang Road Shanghai 200031, China. Department of Biochemistry, Dartmouth Medical School, Hanover, NH 03756 USA. State Key Laboratory of Molecular Biology Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Graduate School of the Chinese Academy of Sciences 320 Yueyang Road Shanghai 200031 Chi
In macrophages, the accumulation of cholesteryl esters synthesized by the activated acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT1) results in the foam cell formation, a hallmark of early atherosclerotic lesions... 详细信息
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