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Effect of Supplemental Sericea Lespedeza Pellets on Internal Parasite Infection and Nutritional Status of Grazing Goats

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Journal of Agricultural Science and Technology(A) 2017年第5期7卷 334-344页

作者： Tiffani Hamilton Thomas Tenill Dill Sandeep Kommuru: Aqiyla Rivers Jorge Mosjidis James Miller Chris Drake Irene Mueller-Harvey Joan Burke Agricultural Research Station Fort Valley State University Fort Valley GA 31030 USA Department of Agronomy and Soils Auburn University Auburn AL 36849 USA Department of Pathobiological Sciences Louisiana State University Baton Rouge LA 70803 USA School of Agriculture Policy and Development University of Reading Reading RG6 6AT UK United States Department of Agriculture Agricultural Research Service Booneville AR 72927 USA

Feeding pelleted sericea lespedeza （SL; Lespedeza cuneata） on pasture can reduce gastrointestinal nematode （GIN） and coccidia （Eimeria spp.） infection in sheep and goats, but effects on nutritional status are unclear. Therefore, a study was completed comparing yearling goats grazing grass pasture supplemented with SL or non-condensed tannins （CT） commercial pellets （control group）, respectively, at 1.5% of body weight for 14 weeks, and then after 14 weeks, they were only fed with non-CT pellets at 2.5% of body weight for additional six weeks. Animal body weight was measured at the start of the trial, the 7th week, 14th week and end of the trial. Fecal samples were taken weekly to determine GIN egg output （fecal egg count; FEC） and coccidial oocyst production （fecal oocyst count; FOC）. Blood samples （to determine packed cell volume; PCV） were taken weekly to monitor anemia status of the goats, and on days 0, 98 and 137 to determine aspartate aminotransferase （AST）, alanine aminotransferase （ALT） and creatine kinase （CK）. The study revealed that supplemental SL leaf meal pellets had no effect on FEC, but reduced FOC （P 〈 0.05） and improved FAMACHA~ scores （P 〈 0.001） in the goats, and the SL supplemented goats tended to gain more weight （P = 0.07） than control animals during the first 49 d, following initiation of pellet feeding. There were no treatment effects on enzymes related to liver function or muscle turnover （AST, ALT and CK）, suggesting that there was no muscle damage due to long-term feeding of SL pellets. In conclusion, feeding supplemental SL pellets at 1.5% of body weight on pasture may be a viable strategy for improving health and productivity of yearling goats.

关键词： Coccidia gastrointestinal nematodes goats micronutrient sericea lespedeza.

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Evaluation of the Fasciolicidal/Nematicidal Efficacy of an Intramuscular Combination of Clorsulon/Levamisole in Naturally Infected Dairy Cattle

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Pharmacology & Pharmacy 2022年第11期13卷 447-456页

作者： Froylán Ibarra-Velarde Yolanda Vera-Montenegro Ignacio Olave-Leiva Antonio Figueroa-Castillo Irene Cruz Mendoza JoaquÍn Ambía-Medina Departamento de Parasitologí a Facultad de Medicina Veterinaria y Zootecnia Universidad Nacional Aut&ograve noma de México Ciudad de México México Universidad Autónoma del Estado de Hidalgo (UAEH) Tulancingo México

The aim of the present study was to assess the fasciolicidal and nematicidal efficacy of a new combination of clorsulon/levamisole, which was formulated for intramuscular administration, in dairy cattle. For the study, sixteen Holstein-Freisian dairy cows were selected for inclusion in the trial based on finding Fasciola hepatica eggs or gastrointestinal nematodes (GIN) in the feces. Ten of these cows were naturally infected with F. hepatica, and 6 were naturally infected with GIN. On Day 0 (zero), all animals were treated with a combination of clorsulon (2.5 mg/kg/IM and levamisole (2.5 mg/kg/IM) administered at the dose recommended by the manufacturer (1 ml/20kg/bw). Subsequently, their feces were analyzed on days 0, 7, 14 and 21 post treatments by the Flukefinder sedimentation method and McMaster technique to determine the percentages of egg reduction in the animals, with reference to the egg load count on day 0. The results obtained in the current work indicated an efficacy of 100% that was determined by the percentage reduction of eggs of F. hepatica and/or GIN. This new fasciolicide/nematicide formulation exerted a remarkable effect and can be considered a new alternative to control F. hepatica and gastrointestinal worms in dairy cattle.

关键词： Efficacy Fasciola Hepatica gastrointestinal nematodes Clorsulon Levamisole Cattle

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