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Development of Bioinfo-Portal Tool for the Analysis of Genomic and Proteomic Data

Journal of Life Sciences 2012年第5期6卷 485-488页

作者： Rana Rehan Khalid Bilal Hussain Muhammad Ali Muhammad Sajjad Ahmad Asma Haque Hira Qamar Department of Bioinformatics and Biotechnology Govt College University Faisalabad Punjab 38000 Pakistan Department of Computer Science Riphah International University Islamabad Punjab 44000 Pakistan

The recent explosion of biological data and the concomitant proliferation of distributed databases make it challenging for biologists and bioinformaticians to discover the best data resources for their needs, and the most efficient way to access and use them For the biologist, running bioinformatics analyses involve a time-consuming management of data and tools. Users need support to organize their work, retrieve parameters and reproduce their analyses. They also need to be able to combine their analytic tools using a safe data flow software mechanism. Finally we have designed a system, Bioinfo-Portal, to provide a flexible and usable web environment for defining and running bioinformatics analyses. It embeds simple yet powerful data management features that allow the user to reproduce analyses and to combine tools using an adobe flex tool. Bioinfo-Portal can also act as a front end to provide a unified view of already-existing collections of bioinformatics resources. Users can analyze genomic and proteomic data by using the tools that has been integrated in the portal （tools for alignments, dotplots, motif detection, domain analysis, profile searching and tertiary structure prediction）. The sequences that user obtained from portal＇s nucleotide and protein databases are easily analyzed by the portal tools on the same interface in no time. User can also take benefit from the animations.

关键词： Bioinfo-Portal analytic tools flexible and usable web environment tertiary structure prediction domain analysis motifdetection alignments.

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