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Mitochondrial DNA sequence diversity in three ethnic populations from the South-west Iran:a preliminary study

Frontiers in Biology 2011年第5期6卷 422-432页

作者： Elham DAVOUDI-DEHAGHANI Ali Mohammad FOROUGHMAND Babak SAFFARI Massoud HOUSHMAND Hamid GALEHDARI Mehdi SHAFA SHARIAT PANAHI Majid YAVARIAN Mohammad Hossein SANATI Somayeh TORFI Department of Genetics Shahid Chamran UniversityAhvaz 61357-43337Iran Medical Genetics Department Tehran University of Medical SciencesTehran 14155-6447Iran Human Genetic Research Group Iranian Academic Center for EducationCulture&Research(ACECR)Fars Province BranchShiraz 71347Iran National Institute for Genetic Engineering and Biotechnology Tehran 14155-6343Iran Hematology Research Center School of MedicineShiraz University of Medical SciencesShiraz 71937Iran

To investigate the genetic structure of human populations in the South-west region of Iran,mitochondrial first hypervariable DNA sequences were obtained from 50 individuals representing three different ethnic groups from Khuzestan *** groups were Shushtari Persians and Chahar Lang Bakhtiyaries from Indo-Europeanspeaking populations and Bani Torof Arabs from Semitic-speaking linguistic *** analysis of mtDNA data showed high similarity of Chahar Lang Bakhtiyaries with other Iranian Indo-European-speaking populations while Shushtaries and Bani Torofs had a closer affinity with Semitic-speaking groups rather than to other Iranian *** relationship of Chahar Lang Bakhtiyaries and Bani Torof Arabs with their neighbor populations can be explained by linguistic and geographic ***,the greater similarity of Shushtari Persians with West Asian Arabs is probably according to high gene flow between *** article represents a preliminary study of three major ethnic groups of South-west Iran which investigates the potential genetic substructure of the region.

关键词： diversity mitochondrial DNA first hypervariable sequence Iran genetic structure population

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