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Risk Factors for Abuse in Children with Congenital Heart Disease Presenting at a Pediatric Tertiary Care Hospital

Congenital Heart Disease 2023年第6期18卷 657-670页

作者： Kristi K.Westphaln Karen Kay Imagawa Lorena Espinosa Smith Julia Srivastava Nancy A.Pike School of Nursing University of CaliforniaLos AngelesCaliforniaUSA Department of Pediatrics Children’s Hospital Los AngelesAudrey Hepburn CARES CenterLos AngelesCaliforniaUSA Keck School of Medicine of the University of Southern California Los AngelesCaliforniaUSA Department of Pediatrics Critical Care MedicineChildren’s Hospital Los AngelesLos AngelesCaliforniaUSA Department of Pediatrics Heart Institute Children’s Hospital Los AngelesLos AngelesCaliforniaUSA

Background:Congenital heart disease(CHD)is a chronic medical condition often diagnosed at birth and requires surgical intervention,multiple hospitalizations,and lifelong *** can put signiﬁcant stress on the family,leading to altered maternal mental health,bonding and attachment issues,and the potential for child *** purpose of this study is to explore the characteristics of a sample of young children with CHD who experienced hospitalization with concurrent concern for child abuse in a free-standing pediatric tertiary care ***:Electronic medical records were reviewed for children aged 0–5 years old who were hospitalized with concern for child abuse between 2016 and *** were extracted related to the history of presenta-tion,and sociodemographics including SDOH,admission,and discharge condition/*** statis-tics were used to characterize the sample and correlations to identify an association with abuse ***:Out of 251 hospitalizations involving concern for child abuse,49(19.5%)had a diagnosis of *** majority of cases were neglect(51%),failure to thrive(FTT),prematurity,history of a feeding tube,developmental delay,and intrauterine drug exposure).Correlations associated with physical abuse were age,maternal mental health,head injury,and history of Child Protective Services(CPS)*** correlated with age,FTT,head injury,history of a feeding tube,previous CPS involvement,and substance *** speciﬁcally related to prenatal substance use included age,maternal mental health status,history of domestic violence,CPS involvement,feeding tube,FTT,lack of housing,employment status,and public ***:Our study highlights the risk for abuse in children with CHD,regardless of defect *** most com

关键词： Child maltreatment intrauterine substance exposure failure to thrive

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Effect of long-term Helicobacter pylori infection on growth of children:a cohort study

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世界儿科杂志:英文版 2016年第2期12卷 196-201页

作者： Celebi Kocaoglu Ahmet Ozel Mustafa Cayci Ece Selma Solak Department of Pediatrics Konya Education and Research Hospital42090 MeramKonyaTurkey Department of Pediatric Nephrology Konya Education and Research Hospital42090 MeramKonyaTurkey Department of Nuclear Medicine Konya Education and Research Hospital42090 MeramKonyaTurkey

Background:The effects of Helicobacter pylori(***)infection on growth are a controversial *** investigated the effects of long-term *** infection on height and weight in ***:A total of 200 children of 7-18 years old suffering from dyspeptic complaints were classified into two groups:*** positive and negative groups,*** the infection was impoved was followed up while performing urea breath test,and according to exposure time to the infection,the children were further divided into group 1(≤1.5 months),group 2(>1.5-≤6 months)and group 3(>6 months).Antropometric measurements were obtained and repeated every six ***:Mean growth velocity scores in the *** positive and negative groups were 0.49±3.85[95%confidence interval(CI):-0.21-1.18]and 1.98±4.42(95%CI:1-2.96),*** difference between both groups was statistically significant(P=0.012).Mean growth velocity scores in groups 1,2 and 3 were 0.96±3.84,0.16±4.51 and-0.85±3.09,*** growth velocity scores of group 3 were significantly lower than those of groups 0 and 1(P=0.005 and P=0.041).The mean weight scores in group 3 were similar to those in group 2,but the scores in group 3 were signifi cantly lower than those in group 1(-1.75±1.05,-1.21±1.37 and-0.88±1.49,respectively).Conclusion:As the duration of exposure is prolonged in children with *** infection,the negative effect of the infection on both height and weight is evident.

关键词： antropometry failure to thrive growth velocity Helicobacter pylori

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New mutation in EPCAM for congenital tufting enteropathy:A case report

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World Journal of Clinical Cases 2020年第20期8卷 4975-4980页

作者： Yan-Qiong Zhou Guo-Sheng Wu Yuan-Mei Kong Xiao-Yuan Zhang Chun-Lin Wang Department of Pediatrics The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina Department of Colorectal and Anal Surgery The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina

BACKGROUND Congenital tufting enteropathy(CTE)is a rare cause of diarrhea in ***,it can result in early-onset of chronic diarrhea and failure to *** with this disease have to depend on total parenteral nutrition(TPN),and eventually small intestine *** epithelial cell adhesion molecule(EPCAM)gene was identified to be associated with ***,we present a case of an infant with CTE due to a mutation not reported in the literature *** SUMMARY A 1-year and 7-mo infant boy exhibited intractable watery diarrhea and mushy stool within 1 wk after birth,for which he had required medical treatment and hospitalization several *** sister presented similar symptoms and died at the age of *** admission,his body weight was 5700 g(-4.8 SDS)and measured 66 cm(-5.4 SDS)in ***,he cannot speak or *** exhibited mild anemia,hypocalcemia,hypomagnesemia,and an infection in the upper respiratory *** sparse and vacuolar degeneration of epithelial cells were reported by small intestine ***-exome sequencing showed a novel homozygous splice mutation(c.657+1[IVS6]G>A)in the EPCAM *** was treated with TPN and recombinant human growth *** 2 mo,his body weight was up to 8500 g and he has been waiting for small bowel *** CTE is rare but *** with CTE require rapid diagnosis and therapy to improve their survival.

关键词： Congenital tufting enteropathy Congenital diarrhea failure to thrive Children Case report

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