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Changes of Cardiac Biomarkers after High-intensity exercise.in Male and Female Elite Athletes of Dragon Boating

Journal of Sports Science 2016年第1期4卷 1-8页

作者： Pascal Bauer Sven Zeiβler Rudiger Walscheid Frank C. Mooren Andree Hillebrecht Department of Cardiology and Angiology University Hospital Giessen Giessen 35390 Germany Faculty of Physical Education and Sports Comenius University Bratislava Bratislava 800 00-899 00 Slovakia Department of Laboratory Medicine Koblenz 56068 Germany Faculty of Sports Medicine Justus-Liebig-University Giessen Giessen 35394 Germany Gesundheitswesen Volkswagen AG Baunatal 34225 Germany

Abstract： This study investigated the effects of three sport-specific high-intensity training units on cardiac biomarker alteration in elite athletes of dragon boating. Thirty six male （age 33 ± 9） and twenty nine female （age 31 ±8） elite athletes, members of the German national team, were examined in their final training camp preparing for world championship. At two time points blood panels （pre-training and one hour post-training） were collected and concentrations of high sensitive troponin T, N-terminal pro brain natriuretic peptide （NT-pro BNP）, ereatine phosphokinase （CPK）, MB-creatine kinase （CKMB） and myoglobin were assessed. After exercise. serum levels ofNT-pro BNP, CPK, myoglobin and CKMB increased significantly （P 〈 0.01 for each） with only few values exceeding the upper reference limits. High sensitive troponin T remained below the limit of detection both before and after exercise.in all athletes. Significant gender-related differences were found with a higher increase ofNT-pro BNP levels in female athletes （P 〈 0.01） compared to males. In contrast, male athletes displayed a significant higher increase of CPK （P 〈 0.01） and myoglobin （P 〈 0.01） compared to female athletes. In conclusion, three high-intensity training units did not lead to elevated high sensitive troponin T concentrations in elite athletes of dragon boating but to significant increases ofNT-pro BNP, CPK and myoglobin levels. This suggests that high-intensity training units do not lead to a cardiac injury in these athletes.

关键词： Cardiac damage high sensitive troponin NT-pro BNP sports medicine exercise.

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The effect of exercise.on dopaminergic brain functions

The effect of exercise on dopaminergic brain functions

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第十五届国际药理学大会

作者： Sutoo Den’ etsu Akiyama Kayo Institute of Medical Science University of TsukubaTsukuba 305-8575Japan Institute of Medical Science University of TsukubaTsukuba 305-8575Japan

＜正＞ The effect of exercise.on brain function was investigated through animal experiments . Previous our studies indicated that calcium increases brain dopamine （DA） synthesis through a calmodu lin- dependent *** leads to increased serum calcium levels,and the calcium is transported to the brain. This in turn enhances brain DA synthesis,and increased DA levels regulate various brain functions. There are abnormally low levels of DA in the neos-triatum and nucleus accumbens of epileptic mice （El mice） and spontaneously hypertensive rats （SHR）. The low DA levels in those animals were improved following intracerebroventricular administration of calcium chloride. Blood pressure and DA levels in SHR were also normalized by exercise. In epileptic El mice,convulsions normalized DA levels and physiologic function. These findings suggest that exercise.or convulsions affect various brain functions through calcium -dependent DA synthesis. This leads to the possibility that symptoms in various diseases that involve DA dysfunction such as Parkinson’s disease or senile dementia might be improved by exercise. Ref.: Neurobiol. Dis. 13: 1-14. 2003.

关键词： calcium/calmodulin dopamine synthesis exercise.

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