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Therapeutic efficiency of short anterior urethral stricture treated with endourethral surgery combined with iridium 192 radiotherapy

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Journal of Pharmaceutical Analysis 2010年第4期22卷 281-284页

作者： Wei-Xing Qu1,Da-Lin He1,Shang-Shu Ding1,Yong-Yi Cheng2,Qing Wang31.Department of Urology,the First Affiliated Hospital,Medical School of Xi’an Jiaotong University,Xi’an 710061 2.Department of Urology,the Third Affiliated Hospital,Medical School of Xi’an Jiaotong University,Xi’an 710068 3.Department of Radiology,the Third Affiliated Hospital,Medical School of Xi’an Jiaotong University,Xi’an 710068,China Department of Urology First Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710061 China Department of Urology Third Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710068 China Department of Radiology Third Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710068 China

Objective To assess the therapeutic efficiency of short anterior urethral stricture treated with endourethral surgery combined with iridium 192 radiation therapy in order to decrease the recurrence rate after endourethral *** A total of 286 patients with anterior urethral stricture(stricture length ranging from 0.5 to 2.5 cm,averaging at 1.6 cm)were divided randomly into two groups after internal urethrotomy and cicatrix *** radiation group of 173 patients was treated as soon as possible with iridium 192 radiation therapy on the stricture sections while the control group of 113 patients was *** recurrence rate was compared between the two groups during one year’s *** Among all the 286 successful operations,stricture recurred in 19 patients of the radiation group(recurrence rate of 10.98%)and in 62 ones of the control group(recurrence rate of 54.86%),with a significant difference(P=0.003).Conclusion It is an effective way to prevent recurrence by treating patients as early as possible with iridium 192 radiation on the stricture sections after endourethral operation on anterior urethral stricture.

关键词： short anterior urethral stricture iridium 192 radiation therapy endourethral surgery

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