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electromagnetic field-enhanced chiral dimanganese trioxide nanoparticles mitigate Parkinson’s disease

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Science China Chemistry 2022年第10期65卷 1911-1920页

作者： Xiuxiu Wang Jing Zhao Weiwei Wang Meiru Lu Aihua Qu Maozhong Sun Xiaoqing Gao Chen Chen Hua Kuang Chuanlai Xu Liguang Xu International Joint Research Laboratory for Biointerface and Biodetection Jiangnan UniversityWuxi 214122China State Key Laboratory of Food Science and Technology Jiangnan UniversityWuxi 214122China Wenzhou Institute University of Chinese Academy of SciencesOujiang LaboratoryWenzhou 325001China

The misfolding and aggregation ofα-synuclein(α-syn)is closely associated with Parkinson’s disease(PD).Here,chiral dimanganese trioxide(Mn_(2)O_(3))nanoparticles(NPs)were prepared for PD treatment enhanced by a noninvasive electromagnetic field(MF).The affinity constants of D-NPs towardα-syn monomer(mono)orα-syn fibril were 3.5 times or 5.2 times higher,respectively,than those of L-NPs,and the mechanical force generated by NPs under a MF further promoted the interaction between NPs andα-syn to amplify the difference between L-NPs and *** the synergy effect of the preferentially affinity ability and MF-induced mechanical forces,D-NPs exhibited a better inhibitory efficiency onα-syn fibrillization than ***,after differentially cellular uptake of L-/D-NPs via the caveolin-mediated pathway,as reactive oxygen species(ROS)-scavengers,D-NPs possess higher efficiency in decreasing intracellular ROS level than L-NPs to provide higher cytoprotective efficiency to neuron *** vivo data showed that after treatment with D-NPs under a MF for 60 days,α-syn concentration in the cerebrospinal fluid of PD mice decreased 81%,while dopamine level in the brain of PD mice increased *** findings indicated the potential of utilizing the synergic interplay of chiral NPs and MF for treating disease and opened a new path to explore the nanoscale chirality for regulating the biological effect.

关键词： electromagnetic field chiral dimanganese trioxide nanoparticles mitigate Parkinson’s Disease

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electromagnetic field produced in high-energy small collision systems within charge density models of nucleons

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Chinese Physics C 2022年第8期46卷 184-195页

作者： Zong-Wei Zhang Xian-Zhuo Cen Wei-Tian Deng School of Physics Huazhong University of Science and TechnologyWuhan 430074China Dalingshan Secondary School DongGuan 523000China

Recent experiments show that Δy,an observable designed to detect the chiral magnetic effect(CME),in small collision systems(p+A) is similar to that in heavy ion collisions(A+A).This introduces a challenge to the existence of the CME because it is believed that no azimuthal correlation exists between the orientation of the magnetic field(Φ_(B)) and participant plane(Φ_(2)) in small collision *** this work,we introduce three charge density models to describe the inner charge distributions of protons and neutrons and calculate the electric and magnetic fields produced in small p+A collisions at both RHIC and LHC *** results show that the contribution of the single projectile proton is the main contributor to the magnetic field after averaging over all *** azimuthal correlation between Φ_(B) and Φ_(2) is small but not ***,owing to the large fluctuation in field strength,the magnetic-field contribution to Δγ may be large.

关键词： electromagnetic field high energy small collision system chiral magnetic effect

The stability of a shearing viscous star with an electromagnetic field

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Chinese Physics B 2013年第5期22卷 175-181页

作者： M. Sharif M. Azama Department of Mathematics University of the Punjab Quaid-e-Azam Campus Lahore-54590 Pakistan Division of Science and Technology University of Education Township Campus Lahore-54590 Pakistan

We analyze the role of the electromagnetic field for the stability of a shearing viscous star with spherical symmetry. Matching conditions are given for the interior and the exterior metrics. We use a perturbation scheme to construct the collapse equation. The range of instability is explored in Newtonian and post Newtonian （pN） limits. We conclude that the electromagnetic field diminishes the effects of the shearing viscosity in the instability range and makes the system more unstable in both Newtonian and post Newtonian approximations.

关键词： gravitational collapse electromagnetic field instability

Forward modeling for “earth-ionosphere” mode electromagnetic field

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Journal of Central South University 2016年第9期23卷 2305-2313页

作者： LI Di-quan Key Laboratory of Metallogenic Prediction of Nonferrous Metals of Ministry of Education (Central South University) Changsha 410083 China School of Geosciences and Info-Physics Central South University Changsha 410083 China Institute of Geology and Geophysics Chinese Academy of Sciences Beijing 100029 China

A fixed artificial source(greater than 200 kW) was used and the source location was selected at a high resistivity region to ensure high emission efficiency. Some publications used the "earth-ionosphere" mode in modeling the electromagnetic(EM) fields with the offset up to a thousand kilometer, and such EM fields still have a signal/noise ratio of 10-20 dB. This means that a new EM method with fixed source is feasible, but in their calculation, the displacement in air was neglected. In this work, some three-layer modeling results were presented to illustrate the basic EM fields' characteristics in the near, far and waveguide areas under "earth-ionosphere" mode, and a standard is given to distinguish the boundary of near, far and waveguide areas. Due to the influence of the ionosphere and displacement current in the air, the "earth-ionosphere" mode EM fields have an extra waveguide zone, where the fields' behavior is very different from that of the far field zone.

关键词： earth-ionosphere mode large power large offset electromagnetic field forward modeling

Analytical solutions to the electromagnetic field in a cylindrical shell excited by external axial current

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Chinese Physics B 2010年第4期19卷 239-246页

作者：吴静肖春燕 School of Automation Science and Electrical Engineering Beihang University

The solutions to the electromagnetic field excited by a long axial current outside a conductive and magnetic cylindrical shell of finite length are studied in this paper. The more accurate analytical solutions are obtained by solving the proper boundary value problems by the separation variable method. Then the solutions are simplified according to asymptotic formulas of Bessel functions. Compared with the accurate solutions, the simplified solutions do not contain the Bessel functions and the inverse operation of the singular matrix, and can be calculated out fast by computers. The simplified solutions are more suitable for the cylindrical shell of high permeability and conductivity excited by a high frequency source. Both of the numerical results and the physical experimental results validate the simplified solutions obtained.

关键词： analytical solution electromagnetic field ferrite shell axial current

Effects of low-frequency electromagnetic field on the surface quality of 7050 aluminum alloy ingots during the hot-top casting process

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International Journal of Minerals,Metallurgy and Materials 2011年第2期18卷 165-168页

作者： Xiang-jie Wang Jian-zhong Cui Yu-bo Zuo Zhi-hao Zhao Hai-tao Zhang Key Lab of electromagnetic Processing of Materials （Ministry of Education） Northeastern University Shenyang 110004 China

To improve the quality of 7050 aluminum alloy ingots, low-frequency electromagnetic （LFE） field was applied during the conventional hot-top casting process. Macrostructures and microstructures of the ingots by the conventional and LFE hot-top casting processes were studied. The experimental results show that when the LFE field is turn off during the hot-top casting process, cold folding appears, and the as-cast structure becomes very coarse. Additionally, the thickness of the shell zone is much thinner during the low-frequency electromagnetic hot-top casting process than that during the conventional hot-top casting process. Some reasons for low-frequency electromagnetic field improving the surface quality, refining the structure of the ingot, and minimizing the thickness of the shell zone have been studied.

关键词： aluminum alloys solidification surface quality electromagnetic field

Comparison study of slag corrosion resistance of MgO–MgAl_(2)O_(4),MgO–CaO and MgO–C refractories under electromagnetic field

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Journal of Iron and Steel Research International 2021年第1期28卷 38-45页

作者： Xin‑ming Ren Bei‑yue Ma Shi‑ming Li Hong‑xia Li Guo‑qi Liu Wen‑gang Yang Fan Qian Shi‑xian Zhao Jing‑kun Yu Key Laboratory for Ecological Metallurgy of Multimetallic Mineral(Ministry of Education) School of MetallurgyNortheastern UniversityShenyang 110819LiaoningChina State Key Laboratory of Advance Refractories Sinosteel Luoyang Institute of Refractories Research Co.Ltd.Luoyang 471039HenanChina

To illuminate the corrosion behavior of MgO-based refractories under electromagnetic field(EMF),herein,the slag corrosion and penetration resistance of MgO–MgAl_(2)O_(4),MgO–CaO,and MgO–C refractories were investigated using the rotary immersion slag resistance test at 1873 K for 1 *** results showed that the order of the good slag resistance of as-tested refractories was MgO–C>MgO–CaO>MgO–MgAl_(2)O_(4).The EMF accelerated the corrosion and penetration of slag to the refractories,which caused the molten slag to be easier into the refractories by natural convection and Marangoni *** addition,the MgO–C refractories did not show an overwhelming advantage in slag resistance because EMF impeded the formation of the dense protection ***,in view of the present results,the MgO–C refractories are still the most promising slag line material for refining furnace among MgO–MgAl_(2)O_(4),MgO–CaO,and MgO–C refractories.

关键词： MgO-based refractory Corrosion Basic slag electromagnetic field

Improved Faddeev-Jackiw quantization of the electromagnetic field and Lagrange multiplier fields

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Chinese Physics C 2008年第10期32卷 788-792页

作者：杨金龙黄永畅 Institute of Theoretical Physics Beijing University of Technology

We use the improved Faddeev-Jackiw quantization method to quantize the electromagnetic field and its Lagrange multiplier fields. The method＇s comparison with the usual Faddeev-Jackiw method and the Dirac method is given. We show that this method is equivalent to the Dirac method and also retains all the merits of the usual Faddeev-Jackiw method. Moreover, it is simpler than the usual one if one needs to obtain new secondary constraints. Therefore, the improved Faddeev-Jackiw method is essential. Meanwhile, we find the new meaning of the Lagrange multipliers and explain the Faddeev-Jackiw generalized brackets concerning the Lagrange multipliers.

关键词： Faddeev-Jakiw method constraint quantization electromagnetic field Lagrange multiplier

Effect of Luteolin on Biochemical,Immunohistochemical,and Morphometrical Changes in Rat Spinal Cord following Exposure to a 900 MHz electromagnetic field

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Biomedical and Environmental Sciences 2020年第8期33卷 593-602页

作者： Ahmad Yahyazadeh Berrin Zuhal Altunkaynak Department of Histology and Embryology Faculty of MedicineKarabuk UniversityKarabukTurkey Department of Histology and Embryology Faculty of MedicineOkan UniversityIstanbulTurkey

Objective This study aimed to investigate the effect of exposure to a 900 MHz electromagnetic field(EMF)on the cervical spinal cord(CSC)of rats and the possible protective effect of luteolin(LUT)against CSC tissue *** Quantitative data were obtained via stereological,biochemical,immunohistochemical,and histopathological *** investigated morphometric value,superoxide dismutase(SOD)level,and the expression of high-mobility group box 1 protein molecules,as well as histological *** The total number of motor neurons in the EMF group significantly decreased in comparison with that in the control group(P<0.05).In the EMF+LUT group,we found a significant increase in the total number of motor neurons compared with that in the EMF group(P<0.05).SOD enzyme activity in the EMF group significantly increased in comparison with that in the control group(P<0.05).By contrast,the EMF+LUT group exhibited a decrease in SOD level compared with the EMF group(P<0.05).Conclusion Our results suggested that exposure to EMF could be deleterious to CSC ***,the protective efficacy of LUT against SC damage might have resulted from the alleviation of oxidative stress caused by EMF.

关键词： electromagnetic field Luteolin Motor neuron Oxidative stress Rat Spinal cord