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Efficacy of electroacupuncture for patients with dry eye syndromes:a randomized controlled trial

Journal of Acupuncture and Tuina Science 2022年第6期20卷 489-498页

作者： ZHANG Dan ZHAO Yan YANG Yanting LIU Xiaoxu ZHAO Yue SHI Zheng HONG Jue LIU Jie MA Xiaopeng Laboratory of Acupuncture-moxibustion and Immunology Shanghai Research Institute of Acupuncture and MeridianShanghai 200030China School of Acupuncture-moxibustion Tuina and RehabilitationYunnan University of Traditional Chinese MedicineKunming 650500China Department of Acupuncture and Moxibustion Guang'anmen HospitalChina Academy of Chinese Medical SciencesBeijing 100053China

Objective To observe the efficacy of electroacupuncture(EA)in treating dry eye syndromes(DES)and its regulatory effects on patient’s quality of life(QOL),anxiety,and *** following a randomized controlled study design,eligible DES patients were allocated to an EA group(EAG)or an acupuncture group(AG).Patients in the AG were intervened by acupuncture alone,while in the EAG,electrical stimulation was applied to Cuanzhu(BL2)and Taiyang(EX-HN5)in addition to the same treatment in the *** in clinical manifestations,ocular surface disease index(OSDI),Schirmer tear test-1(STT-1),tear-film break-up time(TF-BUT),cornea fluorescein staining(CFS),and corneal sensitivity(CS)were observed,as well as changes in the short-form 36-item health survey(SF-36)and hospital anxiety and depression scale(HADS)*** scores of clinical symptoms,OSDI,and CFS decreased significantly in both EAG and AG when compared with the baseline values(P<0.05),respectively,while the TF-BUT and CS increased significantly(P<0.05),and the tear secretion of patients in the EAG increased(P<0.05).Compared with those before treatment,the scores of physical role functioning,general health perception,emotional role functioning,and mental health of patients in both EAG and AG showed significant increases after treatment(P<0.05),together with a marked decrease in the score of anxiety(P<0.05).Compared with the AG,the EAG obtained a more significant increase in STT-1(P<0.05).ConclusionDES patients respond well to both EA and acupuncture treatments,manifested by prolonged TF-BUT and improvement of ***,the two approaches can improve QOL and reduce ***,EA appears more effective in increasing tear secretion than acupuncture alone.

关键词： Acupuncture Therapy Electroacupuncture Point,Cuanzhu(BL2) Point,Taiyang(EX-HN5) dry eye syndromes Quality of Life Emotional Regulation Randomized Controlled Trial

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Summary on Clinical Experience of Acupuncture Treating dry eye syndromes

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Journal of Acupuncture and Tuina Science 2009年第3期7卷 171-174页

作者：马晓芃杨玲莫文权施征赵粹英黄国琪 Shanghai Research Institute of Acupuncture and Meridian

dry eye syndromes （DES） refer to discomfort in the eye region, visual disturbance, poor stability of lacrimal film, inflammation of eye surface and its potential injury due to many factors of abnormal lacrimation. P... 详细信息

关键词： Acupuncture Therapy dry eye syndromes Cupping Therapy Auricular Point Sticking

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dry eye disease due to meibomian gland dysfunction treated with Pinggan Yuyin Qingre formula(平肝育阴清热方):a stratified randomized controlled trial

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Journal of Traditional Chinese Medicine 2023年第4期43卷 770-779页

作者： GAO Yinli LIAN Haihong DENG Shijing DUAN Ying ZHANG Peng WANG Zhiqun ZHANG Yang Department of Traditional Chinese Medicine Beijing Tongren HospitalCapital Medical UniversityBeijing 100005China Beijing Tongren eye Center Beijing Tongren HospitalCapital Medical UniversityBeijing Ophthalmology and Visual Sciences Key LaboratoryBeijing 100005China Beijing Institute of Ophthalmology Beijing Tongren Eye CenterBeijing Key Laboratory of Ophthalmology and Visual SciencesBeijing Tongren HospitalCapital Medical UniversityBeijing 100005China

OBJECTIVE:To observe the clinical efficacy on improving the quality of meibum in patients suffer from dry eye disease(DED)due to meibomian gland dysfunction(MGD)with hyperactivity of Yang due to Yin deficiency pattern after being treated with Pinggan Yuyin Qingre formula(平肝育阴清热方,PGYYQR).METHODS:Totally 120 patients who met the inclusion criteria were included and stratified into three levels according to the level of MGD(1-3),and patients in each level was randomly allocated into the treatment group and control group according to a 1∶1 *** groups were treated with sodium hyaluronate eye drops,and the treatment group was also given PGYYQR *** groups were treated continuously for eight *** score of the properties of meibomian gland(MG)secretion,the score of the palpebral margins,the average noninvasive tear breakup time(NITBUTav),lipid layer thickness(LLT),and Traditional Chinese Medicine(TCM)syndrome efficacy were compared between the two groups after ***:A total of 116 cases were included in the statistical *** differences were statistically significant in the score of the properties of MG secretion,the score of the palpebral margins,and NITBUTav between the two groups after treatment,the treatment group was superior to the control group;there was no evidence of a difference in *** terms of TCM syndrome efficacy,the total effective rate was 84.7%in the treatment group and 50.9%in the control group,with the statistically significant *** of the included cases had adverse ***:PGYYQR is effective in improving the quality of meibum,and the tear film stability which thereby relieving the ocular symptoms in MGD-related DED patients with hyperactivity of Yang due to Yin deficiency pattern.

关键词： Meibomian gland dysfunction dry eye syndromes Yin deficiency Yang hyperactivity Pinggan Yuyin Qingre formula

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Research on Acupuncture-moxibustion for dry eye Syndrome

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Journal of Acupuncture and Tuina Science 2013年第2期11卷 72-78页

作者： Zhang Cui-hong Zhang Lin-lin Ma Xiao-peng Yang Ling Hong Jue LiuJie Wu Ling-xiang Shanghai Research Institute ofAcupuncture and Meridian Shanghai 200030 China Shanghai University of TraditionalChinese Medicine Shanghai201203 China

dry eye syndrome （DES） is a commonly encountered ophthalmological disease, with a relatively high incidence, and expects an effective treatment method. Acupunctureoxibustion therapy promotes tear production of lacrimal gland without causing a trauma, and thus has a great advantage in treating DES. Through literature analysis, this article summarized the research progress in both clinical practice and mechanism of acupuncture- moxibustion in treating DES during the recent 10 years, for providing valuable references for the application of acupuncture-moxibustion for DES.

关键词： dry eye syndromes Acupuncture Therapy Moxibustion Therapy Electroacupuncture Acupuncture Medication Combined Review

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Diverse Needling Methods for dry eye Syndrome:A Randomized Controlled Study

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Journal of Acupuncture and Tuina Science 2013年第2期11卷 84-88页

作者： Guo Meng-hu Cui En-cao Li Xin-yuan Zong Lei Hong Jue Yueyang Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine

Objective： To explore a proper acupuncture treatment protocol for dry eye syndrome （DES）, by comparing the therapeutic effects between ordinary acupuncture and electroacupuncture （EA）. Methods： Forty-seven eligible subjects with DES were randomized into an acupuncture group （n=23） and an EA group （n=24）. With the same acupoint formula, the acupuncture group was treated with ordinary acupuncture, and the EA group was treated with ordinary acupuncture plus electrical stimulation. After a treatment course, eye symptom score, Schirmer test （SIT）, Break-up Time （BUT） of tear film, Corneal Fluorescein Staining （CFS）, and Visual Analogue Scale （VAS） were adopted in evaluation and comparison of the two groups. Results： The total effective rate was 79.2% in the EA group versus 56.5% in the acupuncture group, and the difference was statistically significant （P〈0.05）. After treatment, both groups had marked improvements in eye symptom score, SIT, BUT, CFS, and VAS values （P〈0.001）; the EA group was better than acupuncture group in improving eye symptom score and SIT value （both P〈0.05）; the differences were insignificant in comparing VAS, BUT and CFS results between the two groups （P〉0.05）. Conclusion： Both EA and ordinary acupuncture are effective in treating DES, but EA is better than ordinary acupuncture in improving eye symptom and SIT score.

关键词： Acupuncture Therapy Electroacupuncture dry eye syndromes Randomized Controlled Trial

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