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Detection of drug resistant genes and analysis of the drug resistance of Haemophilus influenzae in a hospital from 2015 to 2017

Detection of drug resistant genes and analysis of the drug r...

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2019年浙江省医学会医学微生物与免疫学分会学术大会

作者： Li Xi Centre of Laboratory Medicine Zhejiang Provincial People’s Hospital

Objective The resistance trend of Haemophilus influenza was studied and its resistance genes were detected in order to provide reference for *** 157 Haemophilus influenzae strains were retrospectively analyzed in our hospital from 2015 to *** strains were identified by NH identification card and their antibiotic susceptibility was measured by HAMEO susceptibility strips;the results of antibiotic susceptibility were judged according to CLSI 2017 standard and were analyzed by WHONET5.6 statistical software;the drug resistance genes was detected by PCR *** Among 157 strains of Haemophilus influenzae,58.5% isolates were isolated from pediatric ***,the type of specimens were mainly from sputum,The drug sensitivity analysis showed that the resistance rate of ampicillin and sulfamethoxazole compound was increased,while ofloxacin and cefotaxime were highly sensitive to these *** addition,the positive rates of TEM and ROB gene were 73.1%and 7.7%,*** Clinical strains of Haemophilus influenzae have high drug resistance rate and multiple drug resistance *** therapy should be based on the results of antimicrobial sensitivity test and avoid unreasonable drug use.

关键词： Haemophilus influenza drug resistance genes drug resistance analysis

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