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Two new diterpene alkaloids from Delphinium chrysotrichum

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Chinese Chemical Letters 2007年第5期18卷 545-547页

作者： Yang Qing He Xiao Mei Wei Yi Li Han Li Ming Gao Department of Applied Chemistry Xi＇ an University of Technology Xi＇ an 710054 China Department of Chemistry Key Laboratory of Polymer Materials of Gansu Province Northwest Normal University Lanzhou 730070 China

Chemical investigation on the ethanol extract from the whole plants of Delphinium chrysotrichum resulted in the isolation of two new diterpene alkaloids named delphatisine A （1） and delphatisine B （2）, respectively. The structures of the new compounds were deduced on the basis of their spectral data （IR, HREIMS, EIMS, 1 D, 2D-NMR）. This is the first report on the isolation of diterpenoid alkaloids from the D. chrysotrichum.

关键词： Delphinium chrysotrichum diterpene alkaloids Delphatisine A Delphatisine B

Two New diterpene alkaloids from the Roots of Spiraea japonica ***

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Chinese Chemical Letters 2001年第1期12卷 67-68页

作者： Hong Ping HE Yue Mao SHEN Xiao Sheng YANG Bin Gui WANG Ling LI Xiao Jiang HAO Laboratory of Phytochemistry Kunming Institute of Botanythe Chinese Academy of SciencesKunming 650204 The Key Laboratory of Chemistry for Natural Products of Guizhou Provence and the Chinese Academy of Sciences

Chemical investigation on the ethanol extract from the roots of Spiraea japonica var. acuta resulted in the isolation of two new diterpene alkaloids named spiratines A and B (1-2), respectively.

关键词： Spiraea japonica var.acuta diterpene alkaloids spiratine A spiratine B.

Diterpenoid alkaloids from a Tibetan medicinal plant Aconitum richardsonianum var. pseudosessiliflorum and their cytotoxic activity

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Journal of Pharmaceutical Analysis 2011年第1期1卷 57-59页

作者： Yang-Qing He Bing-Hua Yao Zhan-Ying Ma Department of Applied Chemistry Xi'an University of Technology Xi'an 710048 China Department of Chemistry Xianyang Normal University Xianyang 712000 China

The chemical constituents from Aconitum richardsonianum *** were *** roots of this plant were extracted three times with 90% EtOH at the room *** ethanol extracts were combined and concentrated under reduced pressure to yield residue,which was suspended in water and successively partitioned with *** chloroform extraction was isolated and purified by silica gel and Sephadex LH-20 column *** compounds were isolated and elucidated as delelatine（1）,isodelpheline（2）,3-acetylaconitine（3）,isoatisine（4）,nordhagenine A（5）and yunaconitine（6）.Compounds 1-5 were obtained from Aconitum Brunneum for the first ***（1）showed significant cytotoxic activities（IC50=4.36 μM）against the human tumor cell line P388.

关键词： Aconitum richardsonianum var.pseudosessiliflorum Ranunculaceae diterpene alkaloids cytotoxic activity

Biological Activity and Molecular Mechanism of Bullatine G

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Medicinal Plant 2023年第2期14卷 90-92,96页

作者： Jian LIU Jinglong CAO Hui XUE Yannan LI Wenshuang HOU Chenghao JIN College of Life Science and Biotechnology Heilongjiang Bayi Agricultural UniversityDaqing 163319China

Bullatine G has many biological effects such as anti-inflammatory,anti-anxiety,anti-tumor,anti-arrhythmia and anti-heart failure *** order to provide a theoretical basis for the further study and clinical application ... 详细信息

关键词： Bullatine G diterpene alkaloids Anti-inflammatory effect Anticancer effect Pharmacological effects

Kiridine, A C18-diterpene Alkaloid from Aconitum kirinense

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Journal of Chinese Pharmaceutical Sciences 2000年第4期9卷 167-169页

作者：冯锋叶文才刘静涵赵守训 Ian D. Williams 车镇涛中国药科大学天然药物化学教研室南京210009 香港理工大学化学系

Kiridine, a new C18-diterpenoid alkaloid, was isolated from the roots of Aconitum kirinense. Its structure was elucidated by MS, 1D- and 2D- NMR, and mono-crystal X-ray analysis. It is the first norditerpene alkaloid ... 详细信息

关键词： Aconitum kirinense Ranunculaceae diterpene alkaloids KiridiP

alkaloids from Delphinium chrysotrichum Finet and Their-Cytotoxic Activity

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Alkaloids from Delphinium chrysotrichum Finet and Their-Cyto...