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Progress in Natural Science:Materials International 2014年第5期24卷 441-445页

作者： Lin Zhu Peng Wan Jiaohong Duan Lili Tan Ke Yang Institute of Metal Research Chinese Academy of Science General Hospital of Shenyang Military Region

Organisms invading root canal systems result in serious pulpal and periapical disease. To eliminate microorganisms and restrain secondary infections, dental materials with antibacterial properties are urgently needed in endodontics. Magnesium is considered as a promising biodegradable and biocompatible implant material. However, there are barely researches about its application in endodontic therapy. This work investigated the in vitro efficacy of magnesium powder against Enterococcus faecalis and Candida albicans compared with a common disinfectant, calcium hydroxide. With Calcium hydroxide served as a comparison it demonstrated the qualified antibacterial and anti-fungus properties of Mg as root canal disinfectant due to its high alkalinity of degradation, and the antimicrobial efficacy enhanced with the decreasing powder size.

关键词： disinfectant Magnesium Antibacterial property Enterococcus faecalis Candida albicans

disinfectant for Urinary Infection Caused by <i>Escherichia coli</i>by Using Natural Oils

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Journal of Biosciences and Medicines 2020年第5期8卷 96-103页

作者： S. Harini Abhipsapanigrahy V. Suneetha Department of Biotechnology School of Biosciences and Technology VIT University Vellore Tamilnadu India

According to the WHO analysis, antibacterial treatment which is preferred for treating peptic ulcers and oral health problems are considered as a major improvement in the treatment but are responsible for several health problems that include vomiting, diarrhea and the increase in the bacterial resistance is a major concern. So, there is an urgent need for a good therapeutic alternative which is effective. Usage of essential oils to treat different ailments is found to be extremely effective with no side effects. Thus, essential oils are gaining importance in treatments due to their antibacterial, antifungal, antiprotozoal properties. Essential oils are also used as aroma therapeutic agents. They are complex mixture of low molecular weight compounds that include terpenoids, phenylpropanoids, oxygenated derivatives (aldehydes, ketones, alcohols, esters) which greatly differ in composition in different essential oils are the major components present. The bioactive properties and their medical potential are widely used in pharmaceutical industries. In this study, we use these essential oils to prepare a disinfectant and analyze the antimicrobial properties using the agar diffusion method. Our major concern in this study is to decrease the growth of Escherichia coli which causes urinary infection, by using disinfectant prepared using a mixture of essential oils of particular concentration.

关键词： Essential Oil Antibacterial Properties Disc Diffusion Method Pharmaceutical disinfectant Urinary Infection

A Moringa Oleifera disinfectant-Sand Filter Integration： A Review of an Alternative Sustainable Technology for Household Water Treatment

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Journal of Environmental Science and Engineering 2011年第9期5卷 1100-1108页

作者： K.A. Yongabi D.M. Lewis P.L. Harris Department of Chemical Engineering The University of Adelaide Adelaide 5005 South Australia Department of Agriculture and Wine Science The University of Adelaide Adelaide 5005 South Australia

This review provides an insight and up-to-date information on the application of Moringa oleifera seeds, the short falls of existing technologies as a coagulant and disinfectant in domestic water treatment. While the coagulant properties are well reported, the disinfectant properties are not well studied. Literatures on low cost alternative technologies such as the application of hiocoagulants and slow sand filters are extensively reported. However, there is limited work addressing the limitations of these technologies that have restricted its widespread use to solve the global soaring water crises. Slow sand filters have a very slow filtration rate that depends on the biofilm layer which takes about 17 days to form. Moringa oleifera treated water cannot last more than 48 hours without bacteria regrowth. Investigation of the best method of isolating coagulant component continues with differing opinions over the nature of its coagulant ingredient not resolved in ongoing literature. An attempt was made in this paper to highlight the advantages of a Moringa disinfectant sand filter hybrid system that can purify water. Microbiological advantages of this system in providing a 100% removal of pathogens, and engineering considerations such as water treatment within an hour residence time, faster flow rates, less clogging and backwashing could be some of the advantages ofa Moringa sand filter system. The need to focus on integrating Moringa and sand filter systems for more practical applications is recommended.

关键词： Moringa oleifera disinfectant sand filter water integration review

Enhanced Disinfection Effect of a Compound disinfectant against Bovine Herpes Virus Type 1 at Low Temperature

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Open Journal of Veterinary Medicine 2013年第5期3卷 247-251页

作者： Makoto Nagai Ryoji Kamimura Reiji Seki Toshiaki Shimoyama Takumi Kubota Junsuke Shirai Department of Veterinary Medicine Faculty and Agriculture Tokyo University of Agriculture and Technology Tokyo Japan

A compound disinfectant, which consisted of didecyldimethylammonium chloride (DDAC), ortho-dichlorobenzene (1,2-dichlorobenzene, ODB), and chlorocresol (4-chloro-3-methylphenol, CC), and its component chemicals were individually tested for effectiveness against bovine herpes virus type 1 (BHV-1). DDAC, DDAC+ODB, DDAC+CC, and DDAC+ODB+CC showed effectiveness against BHV-1 at room temperature. However, ODB, CC, and ODB+CC showed no virucidal effects. The effects of all disinfectants tested were decreased at low temperature. DDAC showed disinfectant effects at a dilution of 1/800 and DDAC+ODB, DDAC+CC, and DDAC+ODB+CC at dilutions of 1/800 and 1/1600 at low temperature in the presence of 2% fetal bovine serum (FBS) but ODB, CC, and ODB+CC showed no virucidal effects. At low temperature and in the presence of 10% FBS, DDAC, DDAC+ODB, and DDAC+CC showed disinfectant effects at dilutions of 1/800, whereas ODB, CC, and ODB+CC showed no virucidal effects. DDAC+ ODB+CC was more effective (at 1/800 and 1/1600) than the other disinfectants under these conditions. In conclusion, a combination of three disinfectant components (DDAC+ODB+CC), enhanced the disinfectant effects at low temperature and in organic matter contamination.

关键词： Bovine Herpes Virus Type 1 Compound disinfectant Enhancing Disinfection Low Temperature Organic Matter Contamination

Comparative Analysis of the Therapeutic Effect of disinfectant and Non-disinfectant on the Separation of the Labia Minora in Infants

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Journal of Clinical and Nursing Research 2021年第6期5卷 159-165页

作者： Qiqi Chen Guangyan Lin Jun Xiong Ping Wei Department of Orthopedics Children's Hospital of Chongqing Medical UniversityChongqingChina International wound stomatostomy nurse Outpatient SurgeryChildren’s Hospital of Chongqing Medical UniversityMinistry of Education Key Laboratory of Child Development and Disorders/National Clinical Research Center for Child Health and Disorders/China International Science and Technology Cooperation base of Child development and Critical Disorders/Children’s Hospital of Chongqing Medical UniversityChongqingP.R China.Chongqing Key Laboratory of Pediatrics.China Outpatient Surgery Children’s Hospital affiliated to Chongqing Medical UniversityChongqingChina

Objective:To compare the effects of the use and non-use of a disinfectant on the outcomes of separation of the labia minora in ***:The patients were randomly divided into an experimental group with 24 cases and a control group with 25 *** the control group,1%iodophor was used to clean and disinfect the large and small labia and the surrounding skin,while normal saline was used in the experimental *** procedures such as the surgery and nursing method were the same in both ***:There were no symptoms of urinary tract infection such as redness of the vulva,swelling,pain,and abnormal urination in the test group and control group after three days of follow-up,and no recurrence was seen at one month of *** was no statistically significant difference between the two groups(P>0.05).Conclusion:Use or non-use of a disinfectant to clean the urethral opening before separation of the labia minora has no significant effect on the outcomes,and does not cause postoperative urinary tract infection ***,non-use of a disinfectant can prevent local irritation and reduce the economic burden on the patients.

关键词： Labial adhesion disinfectant Non-disinfectant

Bioactive Compound from Streptomyces sp. KB1 TISTR2504 as Effective disinfectant against Microorganisms

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Journal of Pharmacy and Pharmacology 2021年第1期9卷 1-7页

作者： Monthon Lertcanawanichakul Kittisak Chawawisit School of Allied Health Sciences Walailak UniversityNakhon Si Thammarat 80160Thailand Food Technology and Innovation Research Center of Excellence Walailak UniversityNakhon Si Thammarat 80160Thailand The Research Unit of Natural Products Utilization Walailak UniversityNakhon Si Thammarat 80160Thailand

A host environment cleaning using disinfectants is the most effective way to prevent the pathogen’s *** study compared the activity among of commercial liquid disinfectants[3%hydrogen peroxide(HP),and 70%ethyl alcohol(EA)]and bioactive-compounds(BCs)from Streptomyces ***1 on indicating microorganisms:Bacillus subtilis ATCC 6633 as representative of spores;Staphylococcus aureus TISTR 517 and clinical methicillin-resistant *** as representative of gram-positive bacteria,Escherichia coli TISTR 887,Pseudomonas aeruginosa TISTR 1467,and extended spectrum beta-lactamase(ESBL)-Klebsiella pneumoniae 342 as representative of gram-negative bacteria;Candida albicans TISTR 5779 as representative of *** showed that *** spores are resistant to 70%EA and BCs from strain KB1-which are biocidal to TISTR strains and clinical isolate MRSA,ESBL-in the free floating microorganism(suspension test).On the other hand,this resistance was not observed with 3%***,3%HP showed more promise for disinfecting microorganisms than that 70%EA and ***,BCs did show the antimicrobial activities equal as 70%*** results might be implied that the using of BCs from selected bacterial strain as effective disinfectant against microorganism,especially vegetative cell,is a sustainable application in nearly future,to reduce using the chemical substances and zero wastes.

关键词： Bioactive compounds disinfectant Streptomyces sp.

Vaccinia virus viability under different environmental conditions and different disinfectants treatment

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Biosafety and Health 2024年第1期6卷 21-27页

作者： Shan Mei Liang Wei Yu Xie Fei Zhao Yu Huang Zhangling Fan Yamei Hu Liming Wang Lingwa Wang Ying Wang Fengwen Xu Fei Guo NHC Key Laboratory of Systems Biology of Pathogens National Institute of Pathogen Biology and Center for AIDS ResearchChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Department of Otolaryngology Head and Neck Surgery Beijing Tongren HospitalCapital Medical UniversityBejing 100730China Clinical Laboratory Emergency General HospitalBeijing 100028China

Monkeypox(mpox)outbreak in 2022 has caused more than 91,000 cases,has spread to 115 countries,regions,and territories,and has thus attracted much *** stability of poxvirus particles in the environment is recognized as an important factor in determining their ***,few studies have investigated the persistence of poxviruses on material surfaces under various environmental conditions,and their sensitivity to ***,we systematically measured the stability of vaccinia virus(VACV)under different environmental conditions and sensitivity to inactivation methods via plaque assay,quantitative real‐time polymerase chain reaction(qPCR),and Gaussia luciferase(G‐luciferase)reporter *** results show that VACV is stable on the surface of stainless steel,glass,clothing,plastic,towel,A4 paper,and tissue and persists much longer at 4℃ and?20℃,but is effectively inactivated by ultraviolet(UV)irradiation,heat treatment,and chemical *** study raises the awareness of long persistence of poxviruses in the environment and provides a simple solution to inactivate poxviruses using common disinfectants,which is expected to help the control and prevention of mpox virus and future poxvirus outbreaks.

关键词： Poxvirus Mpox virus Vaccinia virus Persistence disinfectant

Corrosion Behaviors of disinfectants on Dental Unit Waterlines

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Journal of Wuhan University of Technology(Materials Science) 2023年第4期38卷 938-941页

作者：张玲 QIU Jiajun 邢敏钱文昊 Shanghai Xuhui District Dental Center Shanghai200032China State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai200050China

To investigate the corrosion behaviors and antibacterial effects of sodium hypochlorite(NaClO)and hydrogen peroxide silver ion(HPSI)disinfectants with different concentrations against dental unit waterlines and provide guidance and reference for the use of chemical disinfectants,polyurethane tubes were immersed in ultrapure water(control group),0.1%NaClO,0.5%NaClO,1.0%NaClO,2.5%HPSI,5.0%HPSI,and 10%HPSI solutions for 6,12,and 18 *** angles and Fourier transform infrared spectra were *** morphologies were observed using scanning electron microscopy and antibacterial activity was evaluated using Gram-positive Staphylococcus aureus(***).The results showed that sodium hypochlorite and hydrogen peroxide silver ion disinfectants presented good antibacterial activity against ***,sodium hypochlorite could cause serious damage to the water pipes where corrosion pits and cracks were observed,and increasing the concentration of sodium hypochlorite could accelerate the corrosion *** peroxide silver ion disinfectants had no obvious damage to the water ***,hydrogen peroxide silver ion disinfectants are recommended to use for controlling bacterial infection in dental unit waterlines which can reduce the damage to the water pipes.

关键词： disinfectant dental unit waterlines sodium hypochlorite hydrogen peroxide silver ion

Flashlight contamination and effectiveness of two disinfectants in a stomatology hospital

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International Journal of Nursing Sciences 2017年第2期4卷 169-172页

作者： Dongye Yang Liting Lin Penghao Guo Weina Zhang Xingfang He Qiuyu Huang Longhui Lai Weiqing Long Guanghua School of Stomatology Hospital of StomatologySun Yat-Sen UniversityGuangdong Provincial Key Laboratory of StomatologyGuangzhouChina Department of Clinical Laboratory The First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhouChina

Aim: This study aims to assess the infection risks of flashlight contamination in a stomatology hospital and compare the disinfection effectiveness of alcohol (75%) and disinfecting ***: The flashlight is a basic non-critical medical device in oral and maxillofacial surgery wards. Wounds are mostly found in oral cavities;therefore, reusable flashlights may be a potential source of nosocomial infections (NIs). However, the microbial flora present in flashlights used in hospitals has not yet been explored. Methods: This study investigated the microbial contamination of 41 flashlights used in a stomatology hospital in Guangzhou in March 2016. Results: Results indicated that 75.6%(31/41) of the flashlights had microbial contamination. Gram-positive bacteria accounted for 72.7%(24/33)of the microbial groups contaminating the flashlights, and Gram-negative bacteria (21.2%, 7/33), and fungi (6.1%, 2/33) constituted the remaining contaminants. The predominantly isolated species was Staphyloccus (66.7%, 22/33), especially Staphylococcus aureus (24.2%, 8/33). Approximately 77.3%(17/22) of the types of bacteria detected in the hands were same as those in the corresponding flashlights. Both the bacterial overstandard and S. aureus detection rates of doctors' flashlights were higher than those of nurses' flashlights (16/17 vs. 14/23, 7/17 vs. 1/23, respectively) (P disinfectants performed excellently, and their eligibility rates were not significantly different (17/17 vs. 14/14) (P>0.05). Conclusion: Flashlights are potential causes of NIs. Disinfecting flashlights could be an effective and practical infection control method.

关键词： Flashlights Cross-contamination Infection control disinfectant

Studies of non-metallic organic disinfectants on inactivation of avian influenza viruses

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Health 2013年第8期5卷 1-6页

作者： Huaguang Lu Wiley Lab/Avian Virology Animal Diagnostic Laboratory Department of Veterinary and Biomedical Sciences Pennsylvania State University University Park USA

Six different kinds of non-metallic or organic disinfectants were obtained in this research study including “Neutral Electrolyzed Water”, “M22” organic disinfectant solution, Superoxy Food Wash disinfectant, Hydrogen Peroxide, Clorox Germicidal Bleach and Clidox-S. The effectiveness of these disinfectants was studied against various subtypes of avian influenza virus (AIV). The virus-disinfectant mixtures were prepared in serial dilutions of each disinfectant with a constant virus titer and incubated at ambient temperature in different time intervals for virus inactivation. The virus inactivation results were determined by virus recovery in embryonating chicken eggs. Among the six different kinds of nonmetallic disinfectants obtained for this research project, Neutral Electrolyzed Water, “M22” solution, Clorox Germicidal Bleach and Clidox-S were effectively inactivated AIV with appropriate working dilutions and reaction times. Superoxy Food Wash disinfectant and Hydrogen Peroxide were found having limited effect on virus inactivation with extended exposure times of more than 2 hours. These research findings provide scientific data to poultry industry with guidelines to select and use non-metallic organic disinfectants for poultry flock sanitation and disinfection to effectively prevent and control of avian influenza outbreaks.

关键词： AVian Influenza Virus Non-Metallic disinfectants Neutral Electrolyzed Water M22 Organic disinfectant Superoxy Food Wash Hydrogen Peroxide Clorox Germicidal Bleach Clidox-S