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Spatio-temporal differentiation of Residential Land for Coastal Town: A Case Study of Dalian Jinshitan

Chinese Geographical Science 2016年第4期26卷 566-576页

作者： YANG Jun SUN Jing ZHAO Hongdan XI Jianchao LI Xueming Liaoning Key Laboratory of Physical Geography and Geomatics Liaoning Normal University Key Laboratory of Land Surface Pattern and Simulation Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences

Based on SPOT5 satellite remote sensing images and land use data in five time phases covering the period 1988–2012, the distribution characteristics, spatial differentiation processes, and driving mechanisms affecting the residential land of the Jinshitan Tourist Resort were studied. The work included a combination of GIS technology, adoption of the differentiation index D, and the multi-group differentiation-measure model D(m). The results provided a basis for the following conclusions: 1) From 1988 to 2012, the degree of differentiation of the rural residential land first decreased, and then increased. The general residential, commercial residential and garden-house land-types all showed declining trends, of which the garden-house type presented the most intense volatility. 2) The overall background of the traditional residential land type was gradually replaced by a new residential land type, and the total area of residential land increased year by year, significantly improving the overall residential conditions. The areas of the new residential land type showed growth, and were increasingly widely distributed in the coastal tourist resorts, transportation corridors, and scenic areas. 3) Government policy, social differentiation, market mechanisms, and individual choices(along with other factors) were mutually promoted, although still restrained. However, all of these factors interacted to constrain the developmental direction and the processes affecting tourism real estate in the Dalian Jinshitan Tourist Resort.

关键词： residential space differentiation differentiation degree residential conditions driving mechanism Dalian Jinshitan

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Immunohistochemical Examination of E-Cadherin in the Head and Neck Squamocellular Carcinomas

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International Journal of Otolaryngology and Head & Neck Surgery 2014年第6期3卷 330-336页

作者： Elisabeta Maria Vasca Ioana Lile Amalia Luce Domenico Napolitano Filippo Ricciardiello Teresa Abate Michele Caraglia Tatiana Duminica Virgil Vasca Faculty of Medicine Pharmacy and Dental Medicine“Vasile Goldis”Western University of AradAradRomania Department of Biochemistry Biophysics and General PathologySecond University of NaplesNaplesItaly ENT Division A.O.R.N.CardarelliNaplesItaly ENT Complex Operative Unit Naples University“Federico II”NaplesItaly

E-cadherin is present in the epithelial cells and its aberrant expression is correlated with different kinds of head and neck squamocellular carcinomas. The purpose of the present study was to identify the expression particularities of analyzed E-cadherin in rapport with the localization and the differentiation of various head and neck squamocellular carcinomas. 18 biopsy fragments obtained by squamocellular carcinoma patients (larynx, pharynx, hard palate, tongue, submandibular, lip, gingival sulcus, nasal pyramid, maxillary, zygomatic) were processed by immunohistochemical staining. Immunoreactions for E-cadherin in the tumoral cells were examined according to the score: 0 (0% positive cells of specimen);1 (30% of specimen). The immunohistochemical staining indicated the presence of 12 cases of well-differentiated squamocellular carcinoma (7 cases with score 3, 3 cases with score 2 and 1 case with score 1). Moderately-differentiated carcinomas were observed in the 3 cases (2 with score 2 and 1 with score 1). The poorly-differentiated histopathological type was present in 3 cases (all with score 1). Three types of E-cadherin distribution patterns were found: cytoplasmatic;cytoplasmatic and membranar;membranar. The presence of maximum score (value 3) of E-cadherin was found in well-differentiated squamocellular carcinomas of laryngeal, tongue, lip, nasal pyramid, and zygomatic area origin. A lower value of the score was present in the less differentiated histopathological type.

关键词： Head and Neck Cancer E-Cadherin Cellular Adhesion differentiation degree

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