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Alterations in the Results of Biochemical laboratory tests Due to the Administration of Antihypertensive Drugs

Journal of Pharmacy and Pharmacology 2022年第4期10卷 132-139页

作者： Cleiton Fantin Patrícia Dabila Moraes Aparecido Pedro Kazuya de Arruda Takano Thairineda Silva Jucá Luciana dos Santos Viana Human Genetics laboratory State University of AmazonasManausAmazonas 69065-001Brazil

Objective:Perform a literary review of the interference in the results of biochemical laboratory tests caused by antihypertensive ***:This is a review of the scientific literature with descriptive research performed according to the PRISMA model using the databases PUBMED,SCIELO,MEDLINE,LILACS,and searches of Brazilian Ministry of Health and Federal Pharmacy Council publications,reagent kits and package inserts approved by *** and papers in Portuguese and English were selected,prioritizing the years 2010 to ***:The diuretic class of antihypertensive drugs causes decreases glucose tolerance,thus resulting in an increase in *** long-term use,the drug captopril can increase serum levels of potassium,creatine kinase and decreases blood *** causes an increase in AST *** is associated with an increase in triglyceride levels and a decrease in HDL and glucose *** constant use of losartan results in an increase in HDL,a decrease in uric acid levels and a slight and transient increase in *** the Gold Analisa,Bioclin and Labtest reagent kits,most of the alterations occur due to the increase in levels of serum biomarkers according to the class of the antihypertensive ***:Biochemical alterations in serum can result in false-positive or false-negative reports,since it can be observed that most of the dosages caused increases due to the physiological effect of the *** antihypertensive drugs that showed the highest incidence of interference were captopril,atenolol,losartan and propranolol.

关键词： Antihypertensives captopril biochemical markers losartan propranolol diagnosis and laboratory tests

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