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Impact of age and tumor size on the development of the Kasabach-Merritt phenomenon in patients with kaposiform hemangioendothelioma:a retrospective cohort study

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Precision Clinical Medicine 2023年第2期6卷 81-88页

作者： Jiangyuan Zhou Yuru Lan Tong Qiu Xue Gong Zixin Zhang Chunshui He Qiang Peng Fan Hu Xuepeng Zhang Guoyan Lu Liqing Qiu Feiteng Kong Yongbo Zhang Siyuan Chen Yi Ji Division of Oncology Department of Pediatric SurgeryWest China Hospital of Sichuan UniversityChengdu 610041China Department of Vascular Surgery University Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610032China Department of Pediatric Surgery Chengdu Women and Children’s Central HospitalChengdu 610073China Department of Vascular&Interventional Radiology West China Second University HospitalSichuan UniversityChengdu 610044China Department of Pediatrics West China Second University HospitalSichuan UniversityChengdu 610044China Department of Pediatric Surgery Chengdu Shangjin Nanfu HospitalChengdu 611730China Department of Pediatric Surgery Sichuan Women and Children’s HospitalChengdu 610036China Pediatric Intensive Care Unit Department of Critical Care MedicineWest China Hospital of Sichuan UniversityChengdu 610041China

Introduction The Kasabach–Merritt phenomenon(KMP)is a severe complication of kaposiform hemangioendothelioma(KHE).The risk factors for KMP need further *** The medical records of patients with KHE were *** and multivariate logistic regression models were used for the risk factors for KMP,and the area under the receiver operator characteristic(ROC)curve was used to assess the predictive power of risk *** A total of 338 patients with KHE were *** incidence of KMP was 45.9%.Age of onset(Pcutoffs were 4.75 months for the age of onset(Pcutoff,we found significant differences in tumor morphology,lesion size,hematological parameters,and *** For KHE patients with an onset age5.35 cm,clinicians should be wary of the occurrence of *** management is recommended to improve the prognosis.

关键词： kaposiform hemangioendothelioma Kasabach-Merritt phenomenon age of onset tumor size cutoff values

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