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Design of a Polymer Directional Coupler Electro-Optic Switch with Low Push-Pull Switching Voltage at 1550nm

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Journal of Semiconductors 2008年第11期29卷 2197-2203页

作者：郑传涛马春生闫欣王现银张大明吉林大学电子科学与工程学院集成光电子学国家重点联合实验室吉林大学试验区长春130012

A polymer directional coupler （DC） electro-optic switch with push-pull electrodes and rib waveguides is designed based on the conformal transforming method, image method, coupled mode theory, and electro-optic modulation theory. Its structure and principle are described, the design and optimization are performed, and the characteristics are analyzed, including the coupling length, switching voltage, output power, insertion loss, and crosstalk. To realize normal switching function,the fabrication tolerance,wavelength shift, and coupling loss between a single mode fiber （SMF） and the waveguide are discussed. Simulation results show that the coupling length is 3082μm; the push-pull switching voltage is 2.14V;and the insertion loss and crosstalk are less than 1.14 and -30dB,respectively. The proposed analytical technique on waveguides and electrodes is proven to be accurate and computationally efficient when compared with the beam propa- gation method （BPM） and the experimental results.

关键词： electro-optic switch push-pull electrodes coupling length switching voltage insertion loss crosstalk

Signal Integrity for 0.18μm CMOS Technology

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Journal of Semiconductors 2003年第10期24卷 1030-1034页

作者：孙加兴叶青周玉梅叶甜春中国科学院微电子中心北京100029

The signal integrity problem in 0.18μm CMOS technology is analyzed from *** rules in this phenomenon are found by analyzing the crosstalk delay and noise,which are helpful for the future circuit design.

关键词： interconnect delay signal integrity crosstalk noise

The changing phenotype of microglia from homeostasis to disease

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Translational Neurodegeneration 2012年第1期1卷 55-67页

作者： Xiao-Guang Luo Sheng-Di Chen Department of Neurology First Affiliated Hospital of China Medical UniversityShenyang 110001China Department of Neurology&Institute of Neurology Ruijin Hospital affiliated to Shanghai Jiao Tong UniversityShanghai 200025China

It has been nearly a century since the early description of microglia by Rio-Hortega;since then many more biological and pathological features of microglia have been ***,microglia are generally considered to be beneficial to homeostasis at the resting state through their abilities to survey the environment and phagocytose ***,when activated microglia assume diverse phenotypes ranging from fully inflamed,which involves the release of many pro-inflammatory cytokines,to alternatively activated,releasing antiinflammatory cytokines or neurotrophins,the consequences to neurons can range from detrimental to *** to the different experimental sets and conditions,contradictory results have been obtained regarding the controversial question of whether microglia are“good”or“bad.”While it is well understood that the dual roles of activated microglia depend on specific situations,the underlying mechanisms have remained largely unclear,and the interpretation of certain findings related to diverse microglial phenotypes continues to be *** this review we discuss the functions of microglia in neuronal survival and neurogenesis,the crosstalk between microglia and surrounding cells,and the potential factors that could influence the eventual manifestation of microglia.

关键词： Microglia Neuroprotection Phenotypes Senescence crosstalk

Polymer Arrayed Waveguide Grating with Box-Like Spectral Response

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Journal of Semiconductors 2008年第12期29卷 2307-2310页

作者：秦政坤马春生吉林师范大学信息技术学院四平136000 集成光电子学国家重点联合实验室吉林大学实验区长春130012

An efficient technique is used to flatten the spectral response of an arrayed waveguide grating （AWG） multiplexer. By subtracting an increment from the core width of odd arrayed waveguides and by adding the same increment to that of even arrayed waveguides,a box-like spectral response can be obtained. A 17 × 17 polymer AWG multiplexer with box- like spectral response has been made using FPE polymer materials. Measured result for the AWG shows that the box-like spectral response has a 3dB bandwidth of 0. 476nm, the crosstalk is about or less than - 21dB for every output channel,and the insertion loss is 13-15dB.

关键词： arrayed waveguide grating box-like spectral response 3dB bandwidth crosstalk

Simulation of the Physical Performance of Optical Packet Switching Nodes

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Journal of Shanghai University(English Edition) 2002年第4期6卷 307-312页

作者：王春华李力朱炳春贾潞华 School of Communication and Information Engineering Shanghai University Shanghai China

A graphical and visual simulation system for the study of optical packet switching (OPS) nodes is accomplished. With the simulation system, the effect on physical performance-bit error rate (BER) due to a variety of factors such as the crosstalk parameters of OPS nodes, number of cascaded OPS nodes, length of optical output buffer, traffic load and fluctuation of amplitude of optical signals are evaluated. Reliability of the simulation system is proved by the analytical results obtained in all the above cases.

关键词： optical packet switching optical buffer bit error rate crosstalk interference noise.

The interaction of Notch and Wnt signaling pathways in vertebrate regeneration

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Cell Regeneration 2021年第1期10卷 110-126页

作者： Junying Gao Lixia Fan Long Zhao Ying Su Institute of Evolution&Marine Biodiversity Ocean University of ChinaQingdao 266003ShandongChina College of Fisheries Ocean University of ChinaQingdao 266003ShandongChina College of Marine Life Sciences Ocean University of ChinaQingdao 266003ShandongChina

Regeneration is an evolutionarily conserved process in animal kingdoms, however, the regenerative capacities differfrom species and organ/tissues. Mammals possess very limited regenerative potential to replace damaged organs,whereas non-mammalian species usually have impressive abilities to regenerate organs. The regeneration processrequires proper spatiotemporal regulation from key signaling pathways. The canonical Notch and Wnt signalingpathways, two fundamental signals guiding animal development, have been demonstrated to play significant rolesin the regeneration of vertebrates. In recent years, increasing evidence has implicated the cross-talking betweenNotch and Wnt signals during organ regeneration. In this review, we summarize the roles of Notch signaling andWnt signaling during several representative organ regenerative events, emphasizing the functions and molecularbases of their interplay in these processes, shedding light on utilizing these two signaling pathways to enhanceregeneration in mammals and design legitimate therapeutic strategies.

关键词： Regeneration Notch signaling Wnt signaling crosstalk

Organic Thin Film Electroluminescent Passive Matrix Display

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Journal of Shanghai University(English Edition) 2001年第2期5卷 151-155页

作者： ZHANGBu－xin ZHANGZhi－lin 等 SchoolofMaterialScienceandEngineering ShanghaiUniversitySHanghai200072China

Long life green emitting matrix display based on organic light emitting diode is reported. The pixel number is 96×60, equivalent pixel size 0.4×0.4 mm 2, and the pixel gap 0.1 mm. An image with no crosstalk between pixels is obtained. The average luminance of these pixels at duty cycle of 1/64 is 100 cd/m 2, and the power consumption is 0.6 W. The dark room contrast of 1∶100 is achieved without using a polarization filter.

关键词： organic thin film electroluminescent devices matrix display passive driven crosstalk

Compact,integrated PLZT optical switch array

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Chinese Optics Letters 2015年第11期13卷 37-40页

作者：胡国华戚志鹏恽斌峰张若虎崔一平 Advanced Photonics Center Southeast University

Due to the excellent electro-optic properties of lead lanthanum zirconium titanate(ePb; LaTeZr; TiTO3, PLZT),compact 1 × 2 and 1 × 4 PLZT optical switches with a high response speed are proposed and fabricated successfully in this Letter. By introducing a thin isolating layer between the waveguides and the electrodes, the absorption loss of the fabricated 1 × 2 PLZT switch caused by the electrodes is reduced 8.9 d B with a relatively low driving voltage. The 1 × 2 PLZT switch shows an insertion loss of 18.3 d B and crosstalk of-20.5 d B at an applied voltage of 9.5 V. The fabricated 1 × 4 switch array shows an insertion loss of 20.7 d B and a crosstalk of-20.5 d B at an applied voltage of 13 V. The response time of the switches is less than 27 ns, and the device’s size is only 15 mm × 6 mm. The switches can be used in optical communication systems.

关键词： switch PLZT crosstalk titanate lanthanum waveguide

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机械牵张促进肌细胞成骨相关因子表达

机械牵张促进肌细胞成骨相关因子表达