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Interaction between the left ventricular ejection fraction and left ventricular strain and its relationship with coronary stenosis

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World Journal of Clinical Cases 2023年第10期11卷 2246-2253页

作者： Hai-Yan Gui Shu-Wen Liu Dong-Fang Zhu MRI Room Harbin No.4 HospitalHarbin 150026Heilongjiang ProvinceChina Department of Cardiology Harbin No.4 HospitalHarbin 150026Heilongjiang ProvinceChina

BACKGROUND coronary artery stenosis(CAS)is the most common type of heart disease and the leading cause of death in both men and women *** occurs when the arteries that supply blood to the heart muscle harden and become narrower due to plaque buildup-cholesterol and other material-on their inner *** a result,the heart muscle cannot receive the blood or oxygen it *** heart attacks happen when a blood clot suddenly cuts off the hearts'blood supply,causing permanent heart *** To analyze the relationship between the left ventricular ejection fraction(LVEF),left ventricular strain(LVS),and coronary *** A total of 190 participants were enrolled in this *** control group comprised 93 healthy individuals,and observation group comprised 97 patients with coronary heart disease who were hospitalized between July 2020 and September *** lesions were assessed using the Gensini score,and the LVEF and LVS were measured using magnetic resonance imaging(MRI).The interaction between the LVEF and LVS was examined using a linear regression *** relationship between LVEF and coronary stenosis was examined using Spearman’s *** The LVEF of the observation group was lower than that of the control *** left ventricular end-systolic volume(LVESV)and left ventricular end-diastolic volume(LVEDV)of the observation group were significantly higher than those of the control group(P<0.05).The longitudinal and circumferential strains(LS,CS)of the observation group were significantly higher than those of the control group;however,the radial strain(RS)of the observation group was significantly lower than that of the control group(P<0.05).LVS,LS,and CS were significantly negatively correlated with the LVEF,and RS was positively correlated with the *** were significant differences in the LVEF,LVESV,and LVEDV of patients with different Gensini scores;the LVEF significantly decreased and the LVESV and LVEDV increased w

关键词： Magnetic resonance imaging Left ventricular ejection fraction Left ventricular strain coronary stenosis Left ventricular end-diastolic volume Left ventricular end-systolic volume

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N-terminal pro-B-type natriuretic peptide and diastolic function measurements by adenosine stress echocardiography in prediction of coronary stenosis in patients

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Chinese Medical Journal 2011年第14期124卷 2089-2095页

作者： ZHENG Ping WANG Hao TIAN Yue-qin GUO Yuan-lin HE Zuo-xiang LU Ye ZHENG Xin MA Wen-jun XU Nan SUN Xin ZHANG Ling Department of Echocardiography Cardiovascular Institute and Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100037 China Department of Nuclear Medicine Cardiovascular Institute and Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100037 China Center of coronary Heart Diseases Cardiovascular Institute and Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100037 China Center of Hypertension Cardiovascular Institute and Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100037 China

Background Stress echocardiography is mainly used in detection of coronary artery disease （CAD） and to assess *** study aimed to use adenosine stress echocardiography （ASE） and N-terminal pro-B-type natriuretic peptide （NT-proBNP） to noninvasively assess coronary stenosis in patients with chest pain syndromes or anginal *** NT-proBNP was measured after overnight fast in fifty patients, 42 males and 8 females, who were （57＋11）years old. They then underwent echocardiography before and during adenosine administration. Left ventricular （LV）diastolic function analyzed included mitral annular early （E＇） and late velocity （A＇） both at the mitral septal and lateral level and the mitral inflow to annulus ratio （E/E＇）. coronary angiography was performed the following day after which patients were assigned to three groups： normal results （16 patients）, stenosis 50%-69%（17 patients） and stenosis≥70% （17 patients）.Results NT-proBNP levels in the groups of stenosis 50%-69% and≥ 70% were significantly higher than that in the group with normal results （P=0.014 and P=0.040）. During adenosine stress, the E/E＇ in the group of stenosis≥70% was higher than in the group of normal results （P=0.024）. E＇lateral/A＇lateral in the group of stenosis 50%-69% and E＇septal/A＇septal and E＇lateral/A＇lateral in the group of stenosis≥70% were also decreased during stress compared with baseline （P=0.003,P=0.001, P=0.022）. The variation of E＇septal/A＇septal before and during adenosine stress （△E＇septal/A＇septal） between the groups of normal results and stenosis ≥70% were significantly different （P=0.001）. By receiver operating characteristic （ROC）, the specificity of △E＇septal/A＇septal ≥0.037 predicting coronary stenosis ＜70% was 94%. The sensitivity and specificity of NT-proBNP≥544.6 fmol/ml in predicting coronary stenosis ≥70% were 93% and 75%, ***-proBNP inversely correlated with E＇lateral/A＇lateral （r=-0.390, P=0.014） and positively correlated with E/E＇lateral（r=0.55

关键词： adenosine echocardiography diastole coronary stenosis N-terminal pro-B-type natriuretic peptide

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Non-obstructive coronary Artery Disease in Chinese Patients with Angina Diagnosed by coronary Angiography:A Retrospective Study

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Cardiology Discovery 2021年第4期1卷 223-227页

作者： Chengfei Peng Shaoping Nie Yingxian Sun Hui Chen Zuyi Yuan Yanjun Gong Xiaozeng Wang Yaling Han Department of Cardiology General Hospital of Northern Theater CommandShenyangLiaoning 110016China Department of Cardiology Beijing Anzhen HospitalCapital Medical UniversityBeijing 100029China Department of Cardiology The First Hospital of China Medical UniversityChina Medical UniversityShenyangLiaoning 110001China Department of Cardiology Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Department of Cardiology First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an Jiaotong UniversityXi’anShaanxi 710089China Department of Cardiology Peking University First HospitalPeking UniversityBeijing 100034China

Objective:This study aimed to estimate the proportion of non-obstructive coronary artery disease(CAD)patients in large percutaneous coronary intervention(PCI)centers in ***:The study was conducted at 6 large PCI centers in China from January 1,2013 to December 31,*** and clinical data were collected from medical records,prescription records,and laboratory reports of patients with symptoms of angina who underwent coronary angiography(CAG).Results:A total of 1713 patients were consecutively screened,1600 of whom were included in the *** showed that 300 patients had non-obstructive CAD while 1300 had obstructive *** the 300 patients with non-obstructive CAD,203 displayed mild coronary stenosis(20%-49%)and 91 had normal coronary status(ie,stenosis).Of the 1300 patients with obstructive CAD,61.6%(801/1300)had typical symptoms of angina,compared with 49.3%(148/300)for patients with nonobstructive *** addition,there were more women than men in the non-obstructive CAD group,whereas the reverse was observed among obstructive CAD ***:The prevalence of non-obstructive CAD in the Chinese population with coronary heart disease was estimated to be approximately 20%.Additionally,typical angina symptoms were correlated with obstructive CAD,whereas female gender was identified as a risk factor for non-obstructive CAD.

关键词： Non-obstructive coronary artery disease Percutaneous coronary intervention coronary angiography coronary stenosis

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Left atrial appendage aneurysm: A case report

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World Journal of Clinical Cases 2020年第19期8卷 4443-4449页

作者： Dmitry Vladimirovich Belov Vladimir Ivanovich Moskalev Dmitry Victorovich Garbuzenko Nikolay Olegovich Arefyev Department of Hospital Surgery South Ural State Medical UniversityChelyabinsk 454092Russia Department of Hospital Surgery Federal Center for Cardiovascular SurgeryChelyabinsk 454033Russia Department of Faculty Surgery South Ural State Medical UniversityChelyabinsk 454092Russia Department of Pathological Anatomy and Forensic Medicine South Ural State Medical UniversityChelyabinsk 454092Russia

BACKGROUND An aneurysm of the left atrial appendage is one of the rare but potentially hazardous heart *** risk of lethal complications grows with its *** date,about 150 cases of this defect have been described in the *** present a case of left atrial appendage aneurysm with the deformation of the mitral valve and the left main coronary and circumflex artery,which required mitral valve annuloplasty and bifurcation *** SUMMARY A 58-year-old man presented to our hospital complaining of shortness of breath,general weakness,dizziness during physical exertion,and *** on the results of echocardiography,an aneurysm of the left atrium was suspected.A free-breathing real-time cine magnetic resonance imaging with electrocardiograph synchronization confirmed the diagnosis of left atrial appendage *** patient underwent an aneurysmectomy via a median sternotomy with cardiopulmonary *** transesophageal echocardiography revealed relative mitral insufficiency that was corrected with an annuloplasty *** coronary angiogram showed impaired blood flow in the left main coronary and circumflex artery and 60%*** this reason,bifurcation stenting was *** patient had an uneventful postoperative clinical course and was discharged from the hospital on the 10th day in a satisfactory *** Left atrial appendage aneurysm is a rare and dangerous heart pathology that requires surgery to prevent related complications.

关键词： Atrial appendage Aneurysm Mitral valve insufficiency coronary stenosis Catheter ablation Case report

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Relationship between the number of endothelial progenitor cell and the severity of coronary artery disease

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South China Journal of Cardiology 2012年第3期13卷 188-196页

作者：高达夏菁周建庆廉姜芳杨曦黄晓燕 Department of VIP Ward Lihuili Hospital Department of Emergency Lihuili Hospital Department of Cardiology Lihuili Hospital Department of Laboratory Lihuili Hospital

Background Previous studies have suggested that patients with low endothelial progenitor cell （EPC） counts and impaired endothelial colony forming acti patients with high EPC counts and favorable wty colo have a higher incidence for cardiovascular events compared to ny forming activity. The pathophysiological basis for this finding may be an insufficient endothelial cell repair by EPC. The objective of this study was to determine whether the number of EPCs in peripheral blood was associated with the presence and severity of angiographic stenosis in patients of the late phase after acute myocardial infarction （AMI）. Methods One hundred and one patients undergoing cardiac catheterization in our hospital were enrolled in the study. The number of circulating EPCs was measured by a fluorescent-activated cell sorter （FACS）. Patients with acute coronary syndromes were excluded. Results Compared with patients with normal coronary artery, the number of circulating EPCs was s reduced among patients in the late phase after AMI （P 〈 0.01） We also found that compared with ignificantly the control group, the number of EPCs of single-vessel stenosis group and multi-vessel stenosis group were significantly reduced （P = 0.005 ; P = 0.001 ）. Conclusions The number of EPCs in the peripheral blood is decreased in patients of the late phase after AMI. The EPCs number correlated with angiographic stenosis severity, which suggests that endothelial injury in the deficient circulating EPCs may affect the severity of the heart disorder and the clinical presentations.

关键词： endothelial progenitor cells acute myocardial infarction coronary stenosis cardiovascular riskfactors

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