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DCCP and DICP: Construction and Analyses of Databases for copper-and iron-Chelating Proteins

Genomics,Proteomics & Bioinformatics 2005年第1期 60-65页

作者： Hao Wu1*, Yan Yang1,2*, Sheng-Juan Jiang1, Ling-Ling Chen1#, Hai-Xia Gao1, Qing-Shan Fu1,3, Feng Li1,2,Bin-Guang Ma1, and Hong-Yu Zhang1*1 Shandong Provincial Research Center for Bioinformatic Engineering and Technique, Shandong University ofTechnology, Zibo 255049, China 2 Isotope Research Laboratory, Sichuan Agriculture University, Yaan 625014,China 3 College of Life Sciences, Shandong Normal University, Jinan 250014, China.

copper and iron play important roles in a variety of biological processes, especiallywhen being chelated with proteins. The proteins involved in the metal binding,transporting and metabolism have aroused much interest. To facilitate the studyon this topic, we constructed two databases (DCCP and DICP) containing theknown copper- and iron-chelating proteins, which are freely available from thewebsite http://***/en. Users can conveniently search and browse allof the entries in the databases. Based on the two databases, bioinformatic analyseswere performed, which provided some novel insights into metalloproteins.

关键词： copper and iron database primary sequence analysis secondary structure predic-tion SCOP classification

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DCCP and DICP: Construction and Analyses of Databases for copper-and iron-Chelating Proteins

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Genomics, Proteomics & Bioinformatics 2005年第1期3卷 52-57页

作者： Hao Wu Yan Yang Sheng-Juan Jiang Ling-Ling Chen Hai-Xia Gao Qing-Shan Fu Feng Li Bin-Guang Ma Hong-Yu Zhang Shandong Provincial Research Center for Bioinformatic Engineering and Technique Shandong University ofTechnology Zibo 255049 China Isotope Research Laboratory Sichuan Agriculture University Yaan 625014China College of Life Sciences Shandong Normal University Jinan 250014 China.

copper and iron play important roles in a variety of biological processes, especially when being chelated with proteins. The proteins involved in the metal binding, transporting and metabolism have aroused much interest. To facilitate the study on this topic, we constructed two databases （DCCP and DICP） containing the known copper- and iron-chelating proteins~ which are freely available from the website http：//***/en. Users can conveniently search and browse all of the entries in the databases. Based on the two databases, bioinformatic analyses were performed, which provided some novel insights into metalloproteins.

关键词： copper and iron database primary sequence analysis secondary structure prediction SCOP classification

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