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contact pattern,current immune barrier,and pathogen virulence determines the optimal strategy of further vaccination

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Infectious Disease Modelling 2023年第1期8卷 192-202页

作者： Xiaohao Guo Ziyan Liu Shiting Yang Zeyu Zhao Yichao Guo Guzainuer Abudurusuli Shanlu Zhao Ge Zeng Shixiong Hu Kaiwei Luo Tianmu Chen State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics School of Public HealthXiamen UniversityXiamen City361102Fujian ProvincePeople's Republic of China Hunan Provincial Center for Disease Control and Prevention 405 Furong Middle Road Section OneKaifu DistrictChangsha City410001Hunan ProvincePeople's Republic of China

Background:The current outbreak of novel coronavirus disease 2019 has caused a seriousdisease burden worldwide.Vaccines are an important factor to sustain the epidemic.Although with a relatively high-vaccination worldwide,the decay of vaccine efficacy andthe arising of new variants lead us to the challenge of maintaining a sufficient immunebarrier to protect the population.Method:A case-contact tracking data in Hunan,China,is used to estimate the contactpattern of cases for scenarios including school,workspace,etc,rather than ordinary susceptible population.Based on the estimated vaccine coverage and efficacy,a multi-groupvaccinated-exposed-presymptomatic-symptomatic-asymptomatic-removed model(VEFIAR)with 8 age groups,with each partitioned into 4 vaccination status groups isdeveloped.The optimal dose-wise vaccinating strategy is optimized based on the currentlyestimated immunity barrier of coverage and efficacy,using the greedy algorithm thatminimizes the cumulative cases,population size of hospitalization and fatality respectivelyin a certain future interval.Parameters of Delta and Omicron variants are used respectivelyin the optimization.Results:The estimated contact matrices of cases showed a concentration on middle ages,and has compatible magnitudes compared to estimations from contact surveys in otherstudies.The VEFIAR model is numerically stable.The optimal controled vaccination strategy requires immediate vaccination on the un-vaccinated high-contact population of age30e39 to reduce the cumulative cases,and is stable with different basic reproductionnumbers(R_(0)).As for minimizing hospitalization and fatality,the optimized strategy requires vaccination on the un-vaccinated of both aged 30e39 of high contact frequencyand the vulnerable older.Conclusion:The objective of reducing transmission requires vaccination in age groups ofthe highest contact frequency,with more priority for un-vaccinated than un-fully or fullyvaccinated.The objective of reducing total hospitalization and fatality requires not only tor

关键词： Vaccine Allocation strategy SARS-CoV-2 Optimal control Immune barrier contact pattern Greedy algorithm

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Analysis of Dual-Core Type City and Its Hinterland contact pattern under the Background of High-Speed Rail Networking—Urban Agglomeration in Zhejiang Province as an Example

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Journal of Transportation Technologies 2016年第4期6卷 207-217页

作者： Xiaohong Ren Economics and Management School Chongqing Jiaotong University Chongqing China

Under the background of high-speed rail networking, this paper uses the passenger trains, the type and direction of the railway via Hang Yong and its extension road line, to construct adsorption and dependency index among cities, depict the contact pattern between the Hang Yong dual-core and its hinterland, measure the “net effect” that two center cities (Hangzhou, Ningbo) have on their hinterland, and estimate population agglomeration potential and future possible population flows of Zhejiang Province and the main sample cities. The result shows that, compared with Ningbo, Hangzhou has stronger radiation force to the vast majority of sample cities, and the sample cities affected more by Ningbo mainly concentrates in Ningbo-Taizhou-Wenzhou along;in addition, the sample cities such as Hangzhou, Ningbo and so on show better population agglomeration, then the population “scramble” phenomenon between cities has begun to appear.

关键词： High-Speed Rail Networking contact pattern Measurement

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contact Spot Temperature and the Temperature of External Surfaces in an Electrical Connection

Contact Spot Temperature and the Temperature of External Sur...

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The 26th International Conference on Electrical contacts and the 4th International Conference on Reliability of Electrical Products & Electrical contacts

作者： C.Wilson G.Mclntosh Roland S.Timsit Design Resource Group Richmond HillONCanada L4B 3A9 Snell Infrared Canadian Training Center Richmond HillONCanada L4C 9Y5 Timron Advanced Connector Technologies TorontoONCanada M5M 1L6

Infrared thermography is widely used to monitor the health of electrical power connections in live electrical lines.Although thermal imaging is helpful in locating faulty connections,surface temper

ISBN: (纸本)9781622763139;1622763130

Infrared thermography is widely used to monitor the health of electrical power connections in live electrical lines.Although thermal imaging is helpful in locating faulty connections,surface temper

关键词： infrared thermography electrical interface electrical contacts contact spots temperature electrical contact resistance Temperature interface electronics contact pattern surface temperature electrical connection Computer Simulation Thermography Vital Signs Infrared imaging Electricity Societies Connections temperature gradients Power connection ELECTRIC WIRE

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SIMULATION SYSTEM OF OPERATING PERFORMANCE OF HYPOID GEARS

SIMULATION SYSTEM OF OPERATING PERFORMANCE OF HYPOID GEARS

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2006年中国机械工程学会年会暨中国工程院机械与运载工...

作者： AIZOH Kubo Kyoto University Dept.Prec.Eng. Kyoto606-8501 Japan

A performance simulation program of hypoid gears that can accept measured form deviation of real tooth flank form is developed and gear dynamic performance such as transmission error, contact pattern

关键词： Hypoid gears contact pattern performance simulation vibrational excitation tooth root stress.

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