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Face transplantation for massive mandibular defects: considerations for allograft design and surgical planning

Plastic and Aesthetic Research 2020年第1期7卷 9-16页

作者： William Jackson Palmer Laurel Nelms Boston University School of Medicine BostonMA 02118USA. University of California Riverside School of Medicine RiversideCA 92521USA.

Modern face transplant techniques have advanced to allow for the transfer of vascularized skeletal components in addition to overlying soft *** represents significant opportunity for individuals with mandibular defects that are not amenable to traditional *** must be taken when planning and executing transplants with these complex grafts,as satisfactory functional and aesthetic outcomes rely on achieving proper spatial relationships between the mandible,skull base,and *** donor skeletal elements are included in the allograft and how they are harvested are important considerations in this planning and are associated with *** optimize outcomes in the reconstruction of single-jaw defects,some advocate for transplantation of only the affected jaw while others support bimaxillary *** evidence in this debate is not conclusive at this *** current practice,including donor dentoalveolar anatomy by utilizing a bilateral sagittal split osteotomy of the mandible is favored to optimize outcomes such as dental *** has been suggested that harvesting the mandible at the level of the condyle or even the temporal bone may also be possible and may improve temporomandibular joint-related *** encouraging preclinical evidence,these strategies remain *** allograft design,successful mandibular reconstruction with face transplantation relies on surgical precision in the donor and recipient *** surgical planning,computer-aided design and manufacturing,and intraoperative navigation are technologies currently in use to mitigate operative *** in both cadaveric and clinical face transplantations suggest these technologies are reliable and beneficial,although some room for improvement remains.

关键词： Face transplantation mandibular reconstruction allograft design bimaxillary transplantation temporomandi-bular joint reconstruction computerized surgical planning computer-aided design and manufacturing intraoperative navigation

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