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Corneal sensitivity,ocular surface health and tear film stability after punctal plug therapy of aqueous deficient dry eye

引用

International Journal of Ophthalmology(English edition) 2016年第11期9卷 1598-1607页

作者： Azza Mohamed Ahmed Said Mona Elsayed Farag Tarek Mohamed Abdulla Othman Ali Othman Ziko Wesam Mohamed Osman Ophthalmology Department Faculty of MedicineAin Shams University Pathology Department Faculty of MedicineAin Shams University

AIM： To evaluate the effect of punctal occlusion using thermosensitive（smart plug） versus silicone plug for management of aqueous deficient dry eye on cornea sensitivity, ocular surface health and tear film ***： A comparative prospective interventiona case study included 45 patients with bilateral severe form of aqueous deficient dry eye. In each patient, the smar plug was inserted in the lower punctum of the right eye which was considered as study group 1 and silicone plug was inserted in the lower punctum of the left eye o the same patient which was considered as study group2. All patients were subjected to careful history taking and questionnaire for subjective assessment of severity of symptoms. Corneal sensitivity, corneal fluorescein rose bengal staining, Schirmer＇s I test, tear film break up time and conjunctival impression cytology were performed pre and 1, 3 and 6mo post plug ***： A statistically significant improvement in subjective and objective manifestations occurred following treatment with both types of plugs（P 〈0.01）The thermosensitive plug caused significant overal improvement, decrease in frequency of application o tear substitutes and improvement of conjunctiva impression cytology parameters in the inserted side（P 〈0.01）. Canaliculitis was reported in two eyes（4.4% following punctal occlusion using thermosensitive plug（study group 1）. Spontaneous plug loss occurred in 21eyes（46.6%） in the silicone plug group（study group 2）.CONCLUSION： Improvement of subjective and objective manifestations of aqueous deficient dry eye occurs following punctal plug occlusion. Thermosensitive plug has good patient＇s compliance with fewer complications and lower rates of loss compared to the silicone plug.

关键词： conjunctival impression cytology comealsensitivity corneal fluorescein staining dry eye syndrome Schirmer's test silicone plug thermosensitive smart plug

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