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Issues in the Mining of Heart Failure datasets

International Journal of Automation and computing 2014年第2期11卷 162-179页

作者： Nongnuch Poolsawad Lisa Moore Chandrasekhar Kambhampati John G.F.Cleland Intelligent Systems Research Group(IS Department of Computer Science) University of Hull Hull York Medical School Department of CardiologyUniversity of Hull

This paper investigates the characteristics of a clinical dataset using a combination of feature selection and classification methods to handle missing values and understand the underlying statistical characteristics of a typical clinical dataset. Typically, when a large clinical dataset is presented, it consists of challenges such as missing values, high dimensionality, and unbalanced classes. These pose an inherent problem when implementing feature selection and classification algorithms. With most clinical datasets, an initial exploration of the dataset is carried out, and those attributes with more than a certain percentage of missing values are eliminated from the dataset. Later, with the help of missing value imputation, feature selection and classification algorithms, prognostic and diagnostic models are developed. This paper has two main conclusions: 1) Despite the nature of clinical datasets, and their large size, methods for missing value imputation do not affect the final performance. What is crucial is that the dataset is an accurate representation of the clinical problem and those methods of imputing missing values are not critical for developing classifiers and prognostic/diagnostic models. 2) Supervised learning has proven to be more suitable for mining clinical data than unsupervised methods. It is also shown that non-parametric classifiers such as decision trees give better results when compared to parametric classifiers such as radial basis function networks(RBFNs).

关键词： Heart failure clinical dataset classification clustering missing values feature selection.

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A selective kernel-based cycle-consistent generative adversarial network for unpaired low-dose CT denoising

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Precision clinical Medicine 2022年第2期5卷 125-136页

作者： Chaoqun Tan Mingming Yang Zhisheng You Hu Chen Yi Zhang National Key Laboratory of Fundamental Science on Synthetic Vision Sichuan UniversityChengdu 610065China College of Computer Science Sichuan UniversityChengdu 610065China

Low-dose computed tomography(LDCT)denoising is an indispensable procedure in the medical imaging field,which not only improves image quality,but can mitigate the potential hazard to patients caused by routine *** the improvement in performance of the cycle-consistent generative adversarial network(CycleGAN)due to the well-paired CT images shortage,there is still a need to further reduce image noise while retaining detailed *** by the residual encoder–decoder convolutional neural network(RED-CNN)and U-Net,we propose a novel unsupervised model using CycleGAN for LDCT imaging,which injects a two-sided network into selective kernel networks(SK-NET)to adaptively select features,and uses the patchGAN discriminator to generate CT images with more detail maintenance,aided by added perceptual *** on patch-based training,the experimental results demonstrated that the proposed SKFCycleGAN outperforms competing methods in both a clinical dataset and the Mayo *** main advantages of our method lie in noise suppression and edge preservation.

关键词： cycle-consistent adversarial network selective kernel networks unsupervised low dose CT image denoising clinical dataset

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