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Efficacy of combined cataract extraction and endoscopic cyclophotocoagulation for the reduction of intraocular pressure and medication burden

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International Journal of Ophthalmology(English edition) 2016年第5期9卷 693-698页

作者： Sammie J.Roberts Matthew Mulvahill Jeffrey R.SooHoo Mina B.Pantcheva Malik Y.Kahook Leonard K.Seibold Department of Ophthalmology University of Colorado School of MedicineAnschutz Medical Campus Department of Biostatistics University of ColoradoAnschutz Medical Campus

AIM： To report on the efficacy of combined endoscopic cyclophotocoagulation（ECP） and phacoemulsification cataract extraction（PCE） with intraocular lens placement for reduction of intraocular pressure（IOP） and medication burden in glaucoma.·METHODS： A retrospective case review of 91 eyes（73patients） with glaucoma and cataract that underwent combined PCE/ECP surgery was performed. Baseline demographic and ocular characteristics were recorded,as well as intraocular pressure, number of glaucoma medications, and visual acuity postoperatively with 12-month follow-up. Treatment failure was defined as less than 20% reduction in IOP from baseline on two consecutive visits（at 1, 3, 6, or 12 mo postoperatively）,IOP ≥21 mm Hg or ≤5 mm Hg on two consecutive visits, or additional glaucoma surgery performed within12 mo after PCE/ECP.·RESULTS： Overall, mean medicated IOP was reduced from 16.65 mm Hg at baseline to 13.38 mm Hg at 12mo（P 0.0001）. Mean number of glaucoma medications was reduced from 1.88 medications at baseline to 1.48 medications at 12mo（P =0.0003）. At 3mo postoperatively,the success rate was 73.6%（95%CI： 63.3, 81.5）, 57.1% at6mo（95% CI： 46.3, 66.6）, and 49.7% at 12mo（95% CI：38.9, 59.6）. Patient demographic characteristics were not associated with treatment success. The only ocular characteristic associated with treatment success was a higher baseline IOP.· CONCLUSION： Combined PCE/ECP surgery is an effective surgical option for the reduction of IOP and medication burden in glaucoma patients. Patients withhigher baseline IOP levels are most likely to benefit from this procedure.

关键词： endoscopic cyclophotocoagulation glaucoma cataract extraction

cataract extraction in eyes with Fuchs’endothelial dystrophy in China

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Chinese Medical Journal 2005年第13期118卷 1127-1130页

作者： Ann Mei-Chi Chiu Shandong Eye Institute Qingdao 266071 China

It is a common belief that Fuchs' endothelial dystrophy predominantly affectsCaucasians but rarely Asians. However, in one Japanese study, primary corneal guttae (first stageof Fuchs ' dystrophy) were found in four of 107 cataract patients. With the growing popularity ofphacoemulsification in China in the past decade, the increased incidence of endothelialdecompensation may be due to learning curves among surgeons as well as that the prevalence of Fuchs'dystrophy among Chinese is higher than we thought. Low index of suspicion for Fuchs' dystrophy mayresult in missing of diagnosis and occurrence of endothelial decompensation, particularly when noextra protection is provided for endothelial cells during phacoemulsification. This study was aimedat improving our knowledge about Fuchs' dystrophy among Chinese population and reminding surgeons ofextra endothelial protection during cataract surgery for patients with Fuchs' dystrophy.

关键词： fuchs' endothelial dystrophy cataract extraction phacoemulsification

Graft survival and visual outcome after simultaneous penetrating keratoplasty and cataract extraction

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International Journal of Ophthalmology(English edition) 2013年第3期6卷 385-389页

作者： Mansour M. Al-Mohaimeed Department of Ophthalmology College of Medicine Qassim University

AIM: To evaluate the indications, complications, and visual and graft survival outcomes in eyes that had undergone simultaneous cataract extraction and penetrating keratoplasty (PKP). ·METHODS: We described a retrospective study of 101 patients who had undergone simultaneous cataract extraction and PKP at King Khaled Eye Specialist Hospital between January 1, 2001, and December 31, 2002. All patients were followed up postoperatively with maximum follow-up 68 months. ·RESULTS: The mean age of patients was 61 years. The mean overall follow -up was 27 months. The most common indications for surgery were corneal scarring (45.5% ), previous failed graft (15.8% ), corneal ulcer (12.9% ), Fuchs endothelial dystrophy (8.9% ), stromal dystrophy (2.9% ), and other conditions (14.5% ). Overall, 69 grafts (68.3% ) remained clear at final follow -up. Previous glaucoma or postoperative glaucoma had no statistically significant effects on graft outcome (P >0.05). The graft rejection rate (17.8% ) was a significant risk factor for failure (P =0.00). Age, gender, indications for surgery, corneal graft diameter, and intraoperative vitreous loss had no statistically significant effects on the PKP outcome (P >0.05). Postoperative visual acuity was significantly associated with preoperative visual acuity (P <0.01). ·CONCLUSION: The present study provides evidence that performing a combined procedure results in more rapid visual rehabilitation and good graft clarity.

关键词： penetrating keratoplasty cataract extraction graft failure

Self-management of cataract extraction among diabetes patients

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Journal of Integrative Nursing 2021年第4期3卷 170-175页

作者： Funke Elizabeth AKINTUNDE Olaolorunpo OLORUNFEMI Rasidi Akinade SALAWU Mary Olabisi OYEKANMI Babatunde Abdul-latef ADEYENI Olawale Rasheed OLADAPO Jeminat Omotade SODIMU Department of Medical Surgical Nursing Adeleke University Ede Osun StateNigeria Department of Medical Surgical Nursing Federal University Oye EkitiEkiti StateNigeria Department of Medical Surgical Nursing Babcock UniversityIllisha-RemoOgun StateNigeria Department of Medical Surgical Nursing Achievers UniversityOwoOndo StateNigeria Department of Clinical Nursing Science O.A.U T.H.C Ile-Ife Osun StateNigeria Department of Community Health Nursing School of Nursing AbeokutaOgun StateNigeria

Background:Diabetes-related cataract extraction is a minor surgery required to regain full *** of the recognized factors that can delay or prevent full-vision recovery is poor management,and most of this management is being carried out by patients ***:This study aimed to assess the knowledge of diabetes patients on self-management after cataract extraction in two tertiary hospitals in Osun ***:A cross-sectional descriptive design was conducted among 97 diabetes patients who underwent cataract extraction and were attending clinics and follow-up visits in Osun State.A self-structured questionnaire was used for data ***:Moderate knowledge was found among the participants on an appropriate diet(56.7%),prevention of injury risk(57.5%),prevention of infection risk(50.9%),and low knowledge on the technique of administration of eye drop(60.8%)after cataract extraction,whereas 74.7%of the total respondents were knowledgeable on the indication for follow-up visit after cataract extraction,these results were found to be below the expected knowledge ***:An intensive and comprehensive educational initiative by nurses should be tailored to meet the specific needs of diabetes patients with cataract *** also need to implement the use of checklist which will enhance learning and improve patient understanding of self-management after cataract extraction.

关键词： cataract extraction diabetes patient self-management Nigeria postoperative cataract care

Inhibitory Effect of Short-Term Palpebral Margin Cleaning with Antibiotic Eye Drops on Ocular Surface Flora before cataract extraction:A New Preoperative Antibacterial Method

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Chinese Medical Sciences Journal 2022年第2期37卷 118-126页

作者： Xiaoyong Chen Hongyuan Cai Yinan Liu Jing Hong Department of Ophthalmology Peking University Third HospitalBeijing 100191China

Objective To explore the clinical significance of the combined application of palpebral margin cleaning and antibiotic eye drops in inhibiting bacterial growth in the palpebral margin and conjunctival sacs before cataract *** In this study,61 patients(97 eyes)with age-related cataract who underwent phacoemulsification and intraocular lens implantation were selected,and randomly *** the experimental group,the combined application of palpebral margin cleaning with cotton pads and levofloxacin eye drops was given for three days before the *** the control group,levofloxacin eye drops alone were applied for three consecutive *** samples from the conjunctival sac and eyelid margins were cultivated and identified before and three days after taking antimicrobial measures,*** In the experimental group,the positive rates of the two bacteria samples were 100%(50/50)and 40%(20/50)before and 10%(5/50)and 0%(0/50)after the *** the control group,the positive rates of the two bacteria samples were 97.9%(46/47)and 29.8%(14/47)before and 40.4%(19/47)and 10.6%(5/47)after the *** positive rates between the two groups were not significantly different before taking antimicrobial measures(P=0.485 and 0.395),while they were significantly different after taking antimicrobial measures(P=0.001 and 0.024).Conclusion Combined application of eyelid and palpebral margin cleaning with cotton pads and antibiotic eye drops before cataract extraction imparted excellent antibacterial effects.

关键词： antibiotic prophylaxis cataract extraction eyelid cleaning microbiota

Catquest-9SF functioning over a decade–a study from the Swedish National cataract Register

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Eye and Vision 2020年第1期7卷 553-562页

作者： Mats Lundström Maria Kugelberg Per Montan Ingela Nilsson Madeleine Zetterberg Konrad Pesudovs Anders Behndig Department of Clinical Sciences/Ophthalmology Faculty of MedicineLund UniversityTrossögatan 437137 KarlskronaLundSweden Department of Clinical Neuroscience Division of Ophthalmology and VisionKarolinska InstitutetStockholmSweden St Erik Eye Hospital StockholmSweden Capio Medocular LundSweden Department of Clinical Neuroscience Institute of Neuroscience and PhysiologySahlgrenska Academy at the University of GothenburgGothenburgSweden University of New South Wales AdelaideSAAustralia Department of Clinical Sciences/Ophthalmology UmeåUniversityUmeåSweden

Background:The Swedish National cataract Register(NCR)collects data on cataract surgery outcomes during March,including patient-reported outcomes using the Catquest-9SF questionnaire for over 11 *** studies from NCR have shown that the preoperative visual acuity has improved over *** main purpose of this study was to evaluate the Catquest-9SF Rasch scoring performance in this changing environment.A second purpose was to describe clinical data over the same period for those who completed the ***:The performance of the Catquest-9SF was analysed by a separate Rasch analysis for each year,resulting in a preoperative and postoperative score for each participating patient in the annual *** clinical data and questionnaire scoring were analysed for each year in the period 2008-2018 ***:Data were available for 42,023 eyes for 11 annual cohorts(2008-2018).The psychometric properties of the questionnaire were stable during the study *** separation(precision)for the whole period was 2.58 and varied between 2.45 and *** person reliability was 0.87 and varied between 0.86 and *** targeting of question difficulty to person ability became less accurate over time meaning that the item activities became easier to carry out without *** average targeting for the whole period was−2.06 and changed from−1.92 in 2008 to−2.31 in *** person score improved both before surgery and after surgery,indicating that patients are undergoing surgery at a more able level and getting better *** average improvement by surgery decreased from 3.41 logits in 2008 to 3.21 logits in 2018(p=0.003).Over time,patient age decreased from 75 to 74 years(p<0.001)and the proportion of women decreased from 63.9 to 57.9%(p<0.001).The mean preoperative visual acuity in both the operated eye and the better eye improved over time(0.47 to 0.40 logMAR,p<0.001 and 0.22 to 0.19 logMAR,p<0.001,respectively),as did the mean post

关键词： cataract extraction Outcomes Questionnaire Patient-reported outcomes Rasch analysis

A systematic review of pseudophakic monovision for presbyopia correction

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International Journal of Ophthalmology(English edition) 2017年第6期10卷 992-1000页

作者： Georgios Labiris Aspa Toli Aslin Perente Panagiota Ntonti Vassilios P.Kozobolis Eye Institute of Thrace Alexandroupolis 68100 Greece

A systematic review of the recent literature regarding pseudophakic monovision as a reliable methods for presbyopia correction was performed based on the PubMed, MEDLINE, Nature and the American Academy of Ophthalmology databases in July 2015 and data from 18 descriptive and 12 comparative studies were included in this narrative review. Pseudophakic monosvision seems to be an effective method for presbyopia with high rates of spectacles independence and minimal dysphotopsia side- effects, that should be considered by the modern cataract surgeons.

关键词： pseudophakic monovision presbyopia correc-tion cataract extraction mini-monovision monofocal intraoc-ular lens lens implantation

Effects of phacoemulsification surgery on ocular hemodynamics

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International Journal of Ophthalmology(English edition) 2013年第4期6卷 537-541页

作者： Adem Turk Suleyman Mollamehmetoglu Halil Ibrahim Imamoglu Mehmet Kola Hidayet Erdol Nurettin Akyol Department of Ophthalmology School of MedicineKaradeniz Technical University

AIM:To evaluate the possible effects of phacoemulsification cataract surgery on ocular hemodynamics.·METHODS:In this prospective study,intraocular pressure(IOP),pulsatile ocular blood flow(POBF),and ocular pulse amplitude(OPA) were measured pre-operatively(baseline) and at 1 week and 3 weeks postoperation in 52 eyes of 26 patients(mean age 63.15±10.25 years) scheduled for unilateral phacoemulsification cataract surgery with intraocular lens *** all of the eyes,a blood flow analyzer(Paradigm DICON;Paradigm Medical Industries Inc.;USA) was used to obtain measurements of IOP,POBF,and *** data obtained from operated eyes were compared statistically to untreated fellow phakic eyes of the patients.·RESULTS:For operated eyes,the mean baseline IOP,POBF,and OPA values were 15.9±4.64mmHg,17.41±4.84μL/s,and 2.91 ±1.12mmHg,*** IOP,POBF,and OPA values were 17.19 ±4.34mmHg,17.56 ±6.46μL/s,and3.12 ±1.1mmHg,respectively,in the nonoperated control *** significant differences from baseline measurements were not observed 1 week and 3 weeks postoperation for the operated or nonoperated *** were also no statistically significant differences in any measurements between the operated and nonoperated eyes in all the examination periods(P >0.05for all).·CONCLUSION:Uncomplicated phacoemulsification surgery does not affect ocular hemodynamics in normotensive eyes with cataracts.

关键词： cataract cataract extraction intraocular pressure phacoemulsification regional blood flow

Antibacterial effect of povidone iodine disinfectant and antibiotic eye drops before cataract surgery

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Discussion of Clinical Cases 2022年第3期9卷 5-12页

作者： Qin Zhao Department of Ophthalmology Baogang HospitalBaotouInner MongoliaChina

Objective:Investigate the distribution of bacteria in the conjunctival sac of two groups of cataract patients with different preoperative aseptic treatments,and compare the clinical effects of 0.5%povidone-iodine(PI)and antibiotic eye drops on killing conjunctival sac ***:400 cases of patients(400 eyes)who underwent cataract surgery in the Department of Ophthalmology of Baogang Hospital in Inner Mongolia from October 2019 to October 2020 were selected in a randomized controlled *** were randomly divided into the experimental group(group A)and the control group(group B),with 200 cases in each *** A:the patients were given Gatiﬂoxacin Eye Gel(3 times/day,1 drop/time)combined with Diclofenac Sodium Eye Drops(4 times/day,1 drop/time)before the operation;0.5%PI was administered to irrigate the conjunctival sac,with 0.9%Sodium Chloride Injection washing after 3 min;0.5%PI was administered to irrigate the conjunctival sac after *** corneal epithelium was observed after each *** B:the patients were given Gatiﬂoxacin Eye Gel(3 times/day,1 drop/time)combined with Diclofenac Sodium Eye Drops(4 times/day,1 drop/time)2 days and 1 day before the operation;0.9%Sodium Chloride Injection was administered to irrigate the conjunctival sac before and after surgical *** sac specimens were collected for bacterial culture 2 hours before the operation,after irrigation,and after the *** positive rate and the distribution of bacteria were compared between the two ***:The difference in the positive rate of bacteria in the conjunctival sac between the two groups at different time points had a statistical significance(χ^(2)=11.498,p<.022).Conjunctival sac specimens were collected on admission and 2 hours before the *** was no significant difference in the pathogens with positive results between the two groups(p=.955;p=.073);there was a substantial difference in the distribution of positive

关键词： cataract extraction Povidone-iodine Conjunctival sac irrigation Bacterial culture Corneal epithelium