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Assessing cardiovascular health Using Life＇s Simple 7 in a Chinese Population Undergoing Stroke Prevention

Chinese Medical Journal 2015年第18期128卷 2450-2456页

作者： QiongYang Bin Zhang Pan Deng Lu Chen Jing-Ran Wang Dong-Sheng Fan Department of Neurology Peking University Third Hospital Beijing 100191 China

Background： The American Heart Association/American Stroke Association proposed a metric called Life＇s Simple 7 （LS7） to define cardiovascular health （CVH）. The presence of a large number of ideal components of CVH is associated with lower cardiovascular disease and all-cause mortality. We aimed to assess CVH using LS7 in a Chinese population undergoing primary and secondary stroke prevention. Methods： Patients with either ischemic stroke or cardiovascular risk factors were enrolled in the study from October 2010 to July 2013. LS7 components were scored as poor （0 points）, intermediate （1 point）, or ideal （2 points）. The overall LS7 score was categorized as inadequate （0-4）, average （5-9）, or optimal （10-14） CVH. The Chi-square test, Mann-Whitney U-test, and Kruskal-Wallis test were used. Results： In total, 706 patients were enrolled. （1） The distribution of the overall LS7 score （n = 255） indicated that 9.4%, 82.4%, and 8.2% of the patients had inadequate, average, and optimal CVH, respectively. The proportion of patients with optimal CVH undergoing secondary stroke prevention was lower than that for patients undergoing primary stroke prevention （3.8% vs. 12.8%, P = 0,005）. The vast laaajority of participants （76.1%） presented with 〈2 ideal health components. （2） The proportions of patients with poor, intermediate, and ideal status, respectively, lbr the following LS7 components were assessed： Total cholesterol （n = 275; 5.1%, 73.8%, and 21.1%）, blood pressure （11 = 351 ; 32.5%. 59.0%, and 8.5%）, blood glucose （n = 280; 9.3%, 39.6%, and 51.1%）, physical activity （n = 540; 90.7%, 8.7%, and 0.6%）, diet （n = 524; 0.2%. 92.4%, and 7.4%）, smoking （n = 619： 20.7%, 2.9%, and 76.4%）, and body mass index （n = 259; 6.6%, 35.5%, and 57.9%）. Conclusions： Few Chinese patients undergoing stroke prevention had optimal CVH （determined using LS7）. Additionally, fewer patients undergoing secondary prevention had optimal CVH than those undergoing primary prevention. In particular, ph

关键词： cardiovascular health Life's Simple 7 Lifestyle, Risk Factors Stroke Prevention

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The impact of low ambient temperature on cardiovascular health

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Frigid Zone Medicine 2023年第3期3卷 167-175页

作者： Guoqing Zhang Cuiqing Liu Qinghua Sun School of Public health and Joint China-US Research Center for Environment and Pulmonary Diseases Zhejiang Chinese Medical UniversityHangzhou 310053China Zhejiang International Science and Technology Cooperation Base of Air Pollution and health Hangzhou 310053China

Extreme weather events and climate change have witnessed a substantial increase in recent years,leading to heightened *** rise in abnormal ambient temperatures,both in intensity and frequency,directly and indirectly impacts cardiovascular *** the impact of high ambient temperatures on cardiovascular response is a common concern in the context of global warming,the significance of low temperatures cannot be *** challenges posed by low temperatures contribute to increased cardiovascular morbidity and mortality,posing a significant threat to global public *** review aims to provide an overview of the relationship between low ambient temperature and cardiovascular health,encompassing the burden of cardiovascular outcomes and underlying ***,the review explores strategies for cold adaptation and *** posit that to optimize cold adaptation strategies,future research should delve deeper into the underlying mechanisms of cardiovascular health in response to low ambient temperature exposure.

关键词： low ambient temperature cardiovascular health cold adaptation

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Decoding the nexus:branched-chain amino acids and their connection with sleep,circadian rhythms,and cardiometabolic health

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Neural Regeneration Research 2025年第5期20卷 1350-1363页

作者： Hui Li Laurent Seugnet Department of Neurology Xijing HospitalXi’anShaanxi ProvinceChina Centre de Recherche en Neurosciences de Lyon Integrated Physiology of the Brain Arousal Systems(WAKING)UniversitéClaude Bernard Lyon 1INSERM U1028CNRS UMR 5292BronFrance

The sleep-wake cycle stands as an integrative process essential for sustaining optimal brain function and,either directly or indirectly,overall body health,encompassing metabolic and cardiovascular *** the heightened metabolic activity of the brain,there exists a considerable demand for nutrients in comparison to other *** these,the branched-chain amino acids,comprising leucine,isoleucine,and valine,display distinctive significance,from their contribution to protein structure to their involvement in overall metabolism,especially in cerebral *** the first amino acids that are released into circulation post-food intake,branched-chain amino acids assume a pivotal role in the regulation of protein synthesis,modulating insulin secretion and the amino acid sensing pathway of target of ***-chain amino acids are key players in influencing the brain's uptake of monoamine precursors,competing for a shared *** their involvement in protein synthesis,these amino acids contribute to the metabolic cycles ofγ-aminobutyric acid and glutamate,as well as energy ***,they impact GABAergic neurons and the excitation/inhibition *** rhythmicity of branchedchain amino acids in plasma concentrations,observed over a 24-hour cycle and conserved in rodent models,is under circadian clock *** mechanisms underlying those rhythms and the physiological consequences of their disruption are not fully *** sleep,obesity,diabetes,and cardiovascular diseases can elevate branched-chain amino acid concentrations or modify their oscillatory *** mechanisms driving these effects are currently the focal point of ongoing research efforts,since normalizing branched-chain amino acid levels has the ability to alleviate the severity of these *** this context,the Drosophila model,though underutilized,holds promise in shedding new light on these *** findings indicate its po

关键词： branched-chain amino acids cardiovascular health circadian clock drosophila insulin metabolism sleep γ-aminobutyric acid

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Wearable Alignment‑Free Microfber‑Based Sensor Chip for Precise Vital Signs Monitoring and cardiovascular Assessment

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Advanced Fiber Materials 2022年第3期4卷 475-486页

作者： Liangye Li Yunfei Liu Changying Song Shunfeng Sheng Liuyang Yang Zhijun Yan Dora Juan Juan Hu Qizhen Sun School of Optical and Electronic Information and National Engineering Laboratory for Next Generation Internet Access System(NGIA)and Wuhan National Laboratory for Optoelectronics(WNLO) Huazhong University of Science and TechnologyWuhan 430074HubeiChina Institute for Infocomm Research Singapore 138632Singapore

Continuous pulse wave signals monitoring is the essential basis for clinical cardiovascular diagnosis and *** researches show the majority of current electronic pulse sensors usually face challenges in electrical safety concern,poor durability and demanding precision in position ***,a highly sensitive,inherently electrical safe,robust and alignment-free device is highly ***,we present a wearable alignment-free microfber-based sensor chip(AFMSC)for precise vital signs monitoring and cardiovascular health *** AFMSC comprises an optical micro/nano fber sensor(MNF)and a fexible soft liquid sac while the MNF sensor is used to perceive the physiological signals and the liquid sac is used to eliminate the *** real-time and accurate monitoring of the pulse signals was realized by tracking the optical power variation of transmitted light from ***,the cardiovascular vital signs extracted from radial artery pulse signals were used to evaluate cardiovascular health condition and the results were in accordance with human physiological ***,the pulse signals from diferent arterial area,the respiration signals from chest and the radial pulse signals before and after exercise were detected and *** non-invasive,continuous and accurate monitoring of cardiovascular health based on the reported wearable and alignment-free device is promising in both ftness monitoring and medical diagnostics for cardiovascular disease prevention and diagnosis.

关键词： Optical microfber sensor Wearable,alignment-free Physiological signal cardiovascular health

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The Impact of the Essential Fatty Acids (EFA) in Human health

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Open Journal of Endocrine and Metabolic Diseases 2015年第7期5卷 98-104页

作者： Alberto Krayyem Arbex Vagner Rosa Bizarro Julio Cesar Salles Santos Lis Marina Mesquita Araújo Ana Luísa Conceicao de Jesus Minelli Salles Alves Fernandes Marcela Miranda Salles Denise Rosso Tenório Wanderley Rocha Aline Marcadenti Division of Endocrinology Faculdade IPEMED de Ciências Médicas (IPEMED) Rio de Janeiro Brazil Visiting Scientist of the Harvard School of Public health Harvard University Boston USA Postgraduate Studies Program in Cardiology Instituto de Cardiologia/Fundacao Universitária de Cardiologia do Rio Grande do Sul (IC/FUC) Porto Alegre Brazil Department of Nutrition Universidade Federal de Ciências da Saúde de Porto Alegre (UFSCPA) Porto AlegreBrazil

Linoleic (LA) and α-linolenic acids (ALA) are considered essential fatty acids (EFA) because they are not produced by the human body. This way, EFAs sources must come from the diet. The primary dietary source of n-3 fatty acids is ALA, found in seeds and seed oils. Other important sources are fish oils such as tuna, salmon and herring. Currently, numerous studies suggest possible benefits of essential fatty acids in human health, such as in cardiovascular, cognitive and eye health, and also during pregnancy and childhood. This paper also discusses the impact of fatty acids in human metabolism, and the available evidence regarding its risks. It addresses the relevant debate regarding a general ban of trans fatty acids (TFA) from the world food market, because of the cardiovascular risks associated with its consumption.

关键词： Fatty Acids Linoleic Acid Alpha-Linolenic Acid cardiovascular health Trans Fatty Acids

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