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Application of wearable devices for monitoring cardiometabolic dysfunction under the exposome paradigm

慢性疾病与转化医学:英文版 2023年第3期9卷 200-209页

作者： Haodong Zhang Lingming Hu Pai Zheng Guang Jia Department of Occupational and Environmental Health Sciences School of Public HealthPeking UniversityBeijingChina Peking University Sixth Hospital Peking University Institute of Mental HealthNHC Key Laboratory of Mental Health(Peking University)National Clinical Research Center for Mental Disorders(Peking University Sixth Hospital)BeijingChina

Environmental factors,including chemical/physical pollutants,as well as lifestyle and psychological factors,contribute greatly to the pathways leading to cardiometabolic diseases with a heavy disease burden and economic *** concept of exposomes provides a novel paradigm for combining all exposure characteristics to evaluate disease risk.A solution-like exposome requires technological support to provide continuous data to monitor vital signs and detect abnormal *** devices allow people to conveniently monitor signals during their daily *** new technologies empower users to more actively prevent and manage cardiometabolic disease by reviewing risk factors of the disease,especially lifestyle factors,such as sleeping time,screen time,and mental health *** with multiple sensors can monitor electrocardiography data,oxygen saturation,intraocular pressure,respiratory rate,and heart rate to enhance the exposome study and provide precise suggestions for disease prevention and management.

关键词： cardiometabolic disease environmental factors wearable device

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Effects of chronic decaffeinated green tea extract supplementation on lipolysis and substrate utilization during upper body exercise

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Journal of Sport and Health Science 2021年第2期10卷 237-242页

作者： Sofie Blicher Eric Bartholomae Jochen Kressler Department of Exercise and Nutritional Sciences San Diego State UniversitySan DiegoCA 92113USA

Background:Decaffeinated green tea extract(dGTE)can increase fat oxidation during leg exercise,but dGTE is unsuitable for many people(e.g.,those with injuries/disabilities),and its effects on arm exercise and women are ***:Eight adults(23-37 years old,4 women)performed an incremental arm cycle test to measure peak oxygen uptake(VO_(2_(peak))),followed by four 1-h trials at 50%VO_(2_(peak).Subjects were randomly assigned to 650 mg of dGTE or placebo(PLA)for 4 weeks followed by a 4-week washout and crossover *** samples were obtained pre-exercise and post-exercise for glycerol and free fatty acid *** gases were collected ***:VO_(2) showed no differences across trials((0.83-0.89)±(0.19-0.25)L/min,p=0.460),neither did energy expenditure((264-266)±(59-77)kcal,p=0.420)nor fat oxidation(dGTE=0.11 to 0.12 g/min ***=0.10 to 0.09 g/min,p=0.220).Fat oxidation as percentage of energy expenditure was not different for dGTE ***(23%±12%to 25%±11%vs.23%±10%to 21%±9%,p=0.532).Glycerol concentration increased post-exercise in all trials,independent of treatments(pre=(3.4-5.1)±(0.6-2.6)mg/dL ***=(7.9-9.8)±(2.6-3.7)mg/dL,p=0.867,η^(2)=0.005 for interaction),as did free fatty acid((3.5-4.8)±(1.4-2.2)mg/dL vs.(7.2-9.1)±(2.6-4.5)mg/dL,p=0.981,η^(2)=0.000).Conclusion:Chronic dGTE supplementation had no effect on lipolysis and fat oxidation during arm cycle exercise in men and women.

关键词： Arm exercise cardiometabolic disease Fat oxidation Nutraceutical

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