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Risk factors for postoperative recurrence of cardiac myxoma and the clinical managements： a report of 5 cases in one center and review of literature

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Chinese Medical Journal 2012年第16期125卷 2914-2918页

作者： SHENG Wen-bo LUO Bei-er LiU Yang ZHANG Hao ZOU Liang-jian XU Zhi-yun ZHANG Hai-yan JI Guang-yu Department of Cardiothoracic Surgery Changhai Hospital Second Military Medical University Shanghai 200433 China Department of Cardiothoracic Surgery Department of Prevention and Health Care Changhai Hospital Second Military Medical University Shanghai 200433 China

Background Recurrence or metastasis of myxomas is not rare risk factors for postoperative cardiac myxoma recurrence and to classification. and can lead to malignancy. We aimed to analyze the summarize its clinical characteristics, treatments and Methods The clinical data of 5 patients with recurrent cardiac myxoma were retrospectively analyzed and our clinical experience was summarized. Moreover, the relevant literatures were reviewed. Results All the five cases of primary myxomas were derived from atypical positions. One patient had early distant metastasis, one had family history, and two suffered malignant recurrence. The recurrence interval was （2.30＋2.16） years and the recurrent tumors were all found in different chambers from those of the corresponding primary tumors. Re-operation was performed after recurrence. One patient died of heart failure after malignant recurrence, and the other 4 cases had satisfactory therapeutic outcomes after re-operations. Our experience advocated a clinical classification of ＂typical＂ and ＂atypical＂ cardiac myxoma, the typical myxomas referred to the tumors locating at the left atria, with single pedicle, rooted at or around the fossa ovalis, involving no genetic causes, and the atypical myxomas included the familial tumors, tumors stemming from multiple chambers, rooted in abnormal positions of the left atrium, with evident genetic mutation, or with malignant tendency.

关键词： cardiac myxoma recurrence," classification," clinical management

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Thrombolysis and embolectomy in treatment of acute stroke as a bridge to open-heart resection of giant cardiac myxoma:A case report

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World Journal of Clinical Cases 2021年第25期9卷 7572-7578页

作者： Wan-Sheng Chang Na Li Hui Liu Ji-Jun Yin Hai-Qi Zhang Department of Neurology The Second People's Hospital of Liaocheng CityThe Second Hospital of Liaocheng Affiliated to Shandong First Medical UniversityLinqing 252600Shandong ProvinceChina

BACKGROUND cardiac embolism is a common cause of ischemic stroke in young *** complications associated with atrial myxoma most frequently include cerebral infarct due to *** complete resection of giant cardiac myxoma is the key to its treatment and prevention of stroke *** SUMMARY A 42-year-old,previously healthy woman was admitted to the hospital with sudden-onset inability to speak and right-sided *** sweeping the floor 2 h prior to hospital admission,the patient developed sudden inability to express herself or understand what others were saying,accompanied by dyskinesia of the right limb,inability to walk or hold objects,and involuntary choreiform movements of the left upper *** patient was diagnosed with cerebral embolism and cardiac myxoma,complicated by left middle cerebral artery *** acute stroke was treated with intravenous thrombolytic therapy and arterial embolectomy as a bridging therapy to open resection of left atrial cardiac *** patient condition improved remarkably following initial thrombolysis and embolectomy and subsequently underwent emergency open resection of the atrial cardiac *** had no recurrence during 1-year *** Strong consideration should be given to urgent intravenous thrombolysis(rt-PA,alteplase)in young adult stroke patients at the time of hospital *** present case demonstrated a highly successful outcome that combined thrombolysis and arterial embolus retrieval as a bridge to early complete resection of a giant cardiac myxoma for both stroke treatment and recurrence prevention.

关键词： Stroke Young women cardiac myxoma Bridging Open-heart resection Stroke recurrence Case report

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Familial cardiac myxoma with multifocal recurrences:a case report and review of the literature

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The Journal of Biomedical Research 2011年第5期25卷 368-372页

作者： Hailong Cao Yanhu Wu Jinfu Zhub Yijiang Chen Department of Thoracic and Cardiovascular Surgery the Affiliated Drum Tower Hospital of Nanjing University Medical School Nanjing Jiangsu 210008 China Department of Thoracic and Cardiovascular Surgery the First Affiliated Hospital with Nanjing Medical University Nanjing Jiangsu 210029 China

We report a case of myxoma with multiple recurrences in both the atrium and ventricle in a 26-year-old woman five years after the surgical removal of left atrial myxoma, Her 52-year-old mother had a similar medical history. To our knowledge, this was the first familial case who suffered multifocal cardiac myxoma recurrences without any sign of the myxoma complex. Based on our understanding of the mechanism of recurrence, the approaches to prevent the recurrence, and markers to predict recurrence, we propose that multifocal recurrences, as reported herein, may result from a combination of familial predisposition and multifocal onset. The hi-atrial surgical approach and transesophageal echocardiography are preferred for patients with recurrent cardiac myxomas, especially for those with multiple recurrences and familial myxoma. Immunological and genetic screenings may help to identify family members at risk for developing this disease.

关键词： cardiac myxoma familial multifocal recurrence

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cardiac myxoma: 10 Years Study of Presentations, Resection and Outcome

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World Journal of Cardiovascular Surgery 2021年第10期11卷 83-94页

作者： Vinod Bhan Sri Satyavathi Kanchumarti Sudhakar Rao Velam Vanajakshamma Cardiovascular Thoracic Surgery Department Sri Venkateswara Institute of Medical Sciences Tirupati India Cardiology Department Sri Venkateswara Institute of Medical Sciences Tirupati India

Background: cardiac myxoma is a very rare heart tumor which presents as life threatening mass in cardiac chamber. The tumor may present with vague symptoms which can lead to delay in diagnosis. Methods: 22 patients un... 详细信息

Background: Cardiac myxoma is a very rare heart tumor which presents as life threatening mass in cardiac chamber. The tumor may present with vague symptoms which can lead to delay in diagnosis. Methods: 22 patients underwent complete excision of intracardiac myxoma between January 2011 and December 2020. Majority of the patients were females (60%) with mean age of 48.9 years who presented with symptoms of dyspnea on exertion. 3 patients had significant complications due to myxoma. 2 presenting with tumor embolism and limb ischemia while 1 patient presented with pulmonary edema. All patients were diagnosed by echocardiography which helped in evaluation of size and extent of tumor. Majority of patients underwent trans-septal biatrial approach for tumor excision. Results: 95% of patients survived the operation. The mean tumor size excised was 5.0 ±

关键词： cardiac myxoma Dyspnea Trans-Septal Approach

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Acute Myocardial Infarction: Mode of Revelation of a Left Atrium myxoma

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World Journal of Cardiovascular Surgery 2023年第3期13卷 55-60页

作者： Bréhima Coulibaly Abdoulaye Kanté Mamadou A Keita Mamadou Diakité Bakary Keita Drissa Traoré Nouhoum Ongoïba Patrice Binuani Christophe Baufreton Department of Thoracic and Cardiovascular Surgery CHU Point G Bamako Mali cardiac Surgery Department of the University Hospital of Angers Angers France Cardiology Department CHU Point G Bamako Mali Commune II Reference Health Center Bamako Mali

True, cardiac myxoma is a benign tumor. On the other hand, it is serious by its complications, in particular embolic. The diagnosis of acute coronary syndrome in connection with a myxoma of the left atrium is retained before the association of an emboligenic intracardiac myxoma and an acute coronary syndrome in the absence of atherosclerotic lesions and the absence of intracardiac thrombus. We report a case of left atrium myxoma complicated by acute coronary syndrome in a 50-year-old patient operated on in our department and we will review the literature.

关键词： cardiac myxoma Embolism Acute Coronary Syndrome cardiac Surgery

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Multiple intracranial aneurysms followed left atrial myxoma:case report and literature review

Multiple intracranial aneurysms followed left atrial myxoma:...

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浙江省神经科学学会-神经外科分会成立大会&2015钱江...

作者： Qingsheng Xu Xiaobing Zhang Pan Wu Ming Wang Yongqing Zhou Yiping Feng Department of Neurosurgery the First Affiliated HospitalCollege of MedicineZhejiang University

Cerebral aneurysms follows atrial myxoma is a rare neurological *** report a patient with multiple cerebral aneurysms three years after resection of left atrial myxoma and further review the *** characteristics of these aneurysms are indefinite and *** can occur prior or post the resection of cardiac myxoma. "Metastasize and Infiltrate" theory may be the key mechanism in the formation of these *** resonance imaging(MRI),computed tomography(CT) and angiography are useful in the diagnosis while digital subtraction angiography(DSA)is the best *** are no definite guidelines for therapy of these *** of the cardiac myxomas,chemotherapy,radiotherapy,coil embolization and surgical treatment could be helpful.

关键词： cardiac myxoma intracranial aneurysm embolism metastasize cerebral angiography

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