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Seg-CapNet:A Capsule-Based Neural Network for the Segmentation of Left Ventricle from cardiac magnetic resonance imaging

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Journal of Computer Science & Technology 2021年第2期36卷 323-333页

作者： Yang-Jie Cao Shuang Wu Chang Liu Nan Lin Yuan Wang Cong Yang Jie Li School of Software Zhengzhou UniversityZhengzhou 450000China Center of Modern Analysis and Gene Sequencing Zhengzhou UniversityZhengzhou 450000China Department of Computer Science and Engineering Shanghai Jiao Tong UniversityShanghai 200000China

Deep neural networks(DNNs)have been extensively studied in medical image ***,existing DNNs often need to train shape models for each object to be segmented,which may yield results that violate cardiac anatomical structure when segmenting cardiac magnetic resonance imaging(MRI).In this paper,we propose a capsulebased neural network,named Seg-CapNet,to model multiple regions simultaneously within a single training *** Seg-CapNet model consists of the encoder and the *** encoder transforms the input image into feature vectors that represent objects to be segmented by convolutional layers,capsule layers,and fully-connected *** the decoder transforms the feature vectors into segmentation masks by *** maps of each down-sampling layer in the encoder are connected to the corresponding up-sampling layers,which are conducive to the backpropagation of the *** output vectors of Seg-CapNet contain low-level image features such as grayscale and texture,as well as semantic features including the position and size of the objects,which is beneficial for improving the segmentation *** proposed model is validated on the open dataset of the Automated cardiac Diagnosis Challenge 2017(ACDC 2017)and the Sunnybrook cardiac magnetic resonance imaging(MRI)segmentation *** results show that the mean Dice coefficient of Seg-CapNet is increased by 4.7%and the average Hausdorff distance is reduced by 22%.The proposed model also reduces the model parameters and improves the training speed while obtaining the accurate segmentation of multiple regions.

关键词： capsule neural network image segmentation left ventricle segmentation cardiac magnetic resonance imaging

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Role of cardiac magnetic resonance imaging in troponinemia syndromes

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World Journal of Cardiology 2022年第4期14卷 190-205页

作者： Nhung Nguyen Nguyen Joseph George Assad Giuseppe Femia Andreas Schuster James Otton Tuan Le Nguyen Department of Cardiology Liverpool HospitalLiverpool 2170NSWAustralia Department of Cardiology Campbelltown HospitalCampbelltown 2560NSWAustralia Department of Cardiology and Pneumology University Medical CenterGöttingen 37075Germany

cardiac magnetic resonance imaging(MRI)is an evolving technology,proving to be a highly accurate tool for quantitative *** recently,it has been increasingly used in the diagnostic and prognostic evaluation of conditions involving an elevation in troponin or *** an elevation in troponin is a nonspecific marker of myocardial tissue damage,it is a frequently ordered investigation leaving many patients without a specific ***,the advent of newer cardiac MRI protocols can provide additional *** this review,we discuss several conditions associated with an elevation in troponin such as myocardial infarction,myocarditis,Takotsubo cardiomyopathy,coronavirus disease 2019 related cardiac dysfunction and athlete’s heart syndrome.

关键词： cardiac magnetic resonance imaging Troponin Myocardial infarction Myocarditis Takotsubo cardiomyopathy COVID-19 Athlete’s heart

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cardiac involvement in hydrocarbon inhalant toxicity--role of cardiac magnetic resonance imaging:A case report

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World Journal of Cardiology 2021年第10期13卷 593-598页

作者： George Jolly Shevel Dacosta Davis Saif Ali Lauren Bitterman Ashley Saunders Hana Kazbour Purvi Parwani Division of Cardiology Loma Linda University Medical CenterLoma LindaCA 92354United States Department of Internal Medicine Loma Linda University Medical CenterLoma LindaCA 92354United States

BACKGROUND We report a patient who was diagnosed with toxic myopericarditis secondary to hydrocarbon abuse using cardiac magnetic resonance imaging(CMR).CASE SUMMARY A 25-year-old male presented to emergency department with chest pain for 3 *** also reported sniffing hydrocarbon containing inhalant for the last 1 *** showed elevated troponin and electrocardiography was suggestive of acute *** showed left ventricular(LV)ejection fraction(EF)of 40%.Given patient’s troponin elevation and reduced EF,cardiac catheterization was performed which showed normal *** was performed for myocardial infarction with non-obstructive coronary arteries *** showed borderline LV function with edema in mid and apical LV suggestive of *** CMR can be used to diagnose toxic myopericarditis secondary to hydrocarbon abuse.

关键词： Myocarditis cardiac magnetic resonance imaging Hydrocarbon abuse Hydrocarbon inhalant toxicity Case report

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Role of cardiac magnetic resonance imaging in the diagnosis and management of COVID-19 related myocarditis: Clinical and imaging considerations

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World Journal of Radiology 2021年第9期13卷 283-293页

作者： Lavannya Atri Michael Morgan Sean Harrell Wael AlJaroudi Adam E Berman Division of Cardiology Medical College of GeorgiaAugusta UniversityAugustaGA 30912United States Division of Health Policy Medical College of GeorgiaAugusta UniversityAugustaGA 30912United States Division of Health Economics and Modeling Medical College of GeorgiaAugusta UniversityAugustaGA 30912United States

There is a growing evidence of cardiovascular complications in coronavirusdisease 2019 (COVID-19) patients. As evidence accumulated of COVID-19 mediatedinflammatory effects on the myocardium, substantial attention has beendirected towards cardiovascular imaging modalities that facilitate this *** magnetic resonance imaging (CMRI) is the gold standard for thedetection of structural and functional myocardial alterations and its role inidentifying patients with COVID-19 mediated cardiac injury is growing. Despiteits utility in the diagnosis of myocardial injury in this population, CMRI’s impacton patient management is still evolving. This review provides a framework for theuse of CMRI in diagnosis and management of COVID-19 patients from theperspective of a cardiologist. We review the role of CMRI in the management ofboth the acutely and remotely COVID-19 infected patient. We discuss patientselection for this imaging modality;T1, T2, and late gadolinium enhancementimaging techniques;and previously described CMRI findings in other cardiomyopathieswith potential implications in COVID-19 recovered patients.

关键词： cardiac magnetic resonance imaging COVID-19 Cardiovascular magnetic resonance Myocarditis Coronavirus Cardiovascular complications

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Atrial fibrillation in the elderly： predisposing factors and management

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Journal of Geriatric Cardiology 2017年第3期14卷 185-194页

作者： Juan Lacalzada-Almeida Javier Garcia-Niebla Department of Cardiology Hospztal Umversitarlo de Canarias Tenerife Spain Servicios Sanitarios del Area de Salud de El Hierro Valle del Golfo Health Center El Hierro Spain

In the last twenty years, new imaging techniques to assess atrial function and to predict the risk of recurrence of atrial fibrillation after treatment have been developed. The present review deals with the role of these techniques in the detection of structural and functional changes of the atrium and diagnosis of atrial remodeling, particularly atrial fibrosis. Echocardiography allows the detection of anatomical, functional changes and deformation of the atrial wall during the phases of the cardiac cycle. For this, adequate acquisition of atrial images is necessary using speckle tracking imaging and interpretation of the resulting strain and strain rate curves. This allows to predict new-onset atrial fibrillation and recurrences. Its main limitations are inter-observer variability, the existence of different software manufacturers, and the fact that the software used were originally developed for the evaluation of the ventricular function and are now applied to the atria. cardiac magnetic resonance, using contrast enhancement with gadolinium, plays a key role in the visualization and quantification of atrial fibrosis. This is the established method for in vivo visualization of myocardial fibrotic tissue. The non-invasive evaluation of atrial fibrosis is associ- ated with the risk of recurrence of atrial fibrillation and with electro-anatomical endocardial mapping. We discuss the limitations of these techniques, derived from the difficulty of demonstrating the correlation between fibrosis imaging and histology, and poor intra- and inter- observer reproducibility. The sources of discordance are described, mainly due to image acquisition and processing, and the challenges ahead in an attempt to eliminate differences between operators.

关键词： Atrial fibrillation Atrial fibrosis cardiac magnetic resonance imaging Speckle tracking echocardiography Strain

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Congenital Absence of Pericardium:The Largest Systematic Review in the Field on 247 Worldwide Cases(1977-Now)

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Congenital Heart Disease 2023年第6期18卷 595-610页

作者： Pier Paolo Bassareo Aurelio Secinaro Paolo Ciliberti Massimo Chessa Marco Alfonso Perrone Kevin Patrick Walsh Colin Joseph Mcmahon Mater Misericordiae University Hospital National Adult Congenital Heart Disease ServiceDublinD07 R2WYIreland Children’s Health Ireland Crumlin DublinIreland School of Medicine University College of DublinDublinIreland Advanced Cardiovascular imaging Unit Bambino GesùChildren’s HospitalIRCCSRomeItaly Department of cardiac Surgery CardiologyHeart and Lung Transplantation Bambino Gesu’Children’s HospitalIRCCSRomeItaly Adult Congenital Heart Disease UNIT Paediatric and Adult Congenital Heart CentreIRCCS-Policlinico San DonatoSan Donato MilaneseMilanItaly School of Medicine Vita Salute San Raffaele UniversityMilanItaly Division of Cardiology and CardioLab Department of Clinical Sciences and Translational MedicineUniversity of Rome Tor VergataRomeItaly

Background:Congenital absence of pericardium(CAP),also known as pericardial agenesis,represents an uncommon cardiac abnormality and mostly incidental *** can be subdivided into complete and partial(left or right-sided)*** of its infrequency,just case reports and a few case series have been released so *** paper represents the largest systematic review in the *** features(age at diagnosis,type,gender,clinical presentation,electrocardiography,imaging(ultrasounds,CT/MRI),concomitant cardiac defects,and outcome)were ***:The electronic database PubMed was investigated from its establishment up to July 15th,*** case reports and case series were *** studies,papers that were not in English,Spanish,and Italian,and those manuscripts not reporting at least seven of the nine analysed *** ruled *** analysed data were reported mostly in terms of ***:One hundred eighty studies were included encompassing 247 *** than half of reviewed CAP cases were in males(63.2%).The mean age at diagnosis was 31.8±19.3 years;a range of 32 weeks of gestation-81 years).23.5%of the patients did not report any *** most common clinical presentations were chest pain(35.2%)and dyspnoea(29.2%).The most commonly seen ECG changes were right axis deviation(28.7%)and right bundle branch block(23.9%).CAP was suspected or diagnosed by echocardiography in 20.1%of *** diagnosis was made by CT and/or MRI in 61.9%of *** was left-sided in 71.2%,complete in 23.1%,and right-sided in 5.7%.A concomitant congenital heart defect was found in 22.7%,especially in the form of atrial septal defect(6.5%)and patency of ductus arteriosus(2.8%).The pericardial repair was required in 12.9% of the incomplete forms of the *** did the complete form require surgical *** outcome appeared favourable in the vast majority of cases,with just 18 deaths(7.3%).Discussion:The main limitation of this syste

关键词： Congenital absence pericardium pericardial agenesis electrocardiography echocardiography computed tomography cardiac magnetic resonance imaging

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Prognostic Value of Feature-Tracking Circumferential Strain in Dilated Cardiomyopathy Patients with Severely Reduced Ejection Fraction Incremental to Late Gadolinium Enhancement

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Current Medical Science 2021年第1期41卷 158-166页

作者： Shcng-lei SHU Jing WANG Cheng WANG Feng ZHU Yu-xi JIA Lan ZHANG Xiao-yue ZHOU Tian-jing ZHANG Chuan-sheng ZHENG Department of Radiology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China Hubei Province Key Laboratory of Molecular imaging Wuhan430022China Department of Cardiology Institute of CardiologyUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China MR Collaboration Siemens HealthineersShanghai201318China Philips Healthcare Guangzhou510055China

Myocardial fiber deformation measurements have been reported to be associated with adverse outcomes in patients with acute heart failure and those with myocardial ***,few studies have addressed the prognostic value of global circumferential strain(GCS)in dilated cardiomyopathy(DCM)patients with severely impaired systolic *** study aimed to evaluate the prognostic value of cardiac magnetic resonance(CMR)-derived GCS in DCM patients with severely reduced *** DCM patients with severely reduced ejection fraction(EFcardiac death(SCD).A total of 129 patients with a mean EF of 15.33%(11.36%–22.27%)were *** a median follow-up of 518 days,endpoint events occurred in 50 *** with GCS≥the median(−5.17%)had significantly reduced event-free survival as compared with those with GCSimaging risk factors including extent of late gadolinium enhancement(LGE)(Pimaging risk factors including LGE.

关键词： cardiac magnetic resonance imaging circumferential strain prognosis late gadolinium enhancement dilated cardiomyopathy

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Isolated left ventricular apical hypoplasia:Systematic review and analysis of the 37 cases reported so far

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World Journal of Clinical Cases 2023年第23期11卷 5494-5503页

作者： Pier Paolo Bassareo Sophie Duignan Adam James Esme Dunne Colin J McMahon Kevin P Walsh University College of Dublin School of Medicine and Department of Cardiology at Mater Misericordiae University HospitalDublin D07 R2WYIreland Department of Cardiology Children's Health CrumlinDublin D12 N512Ireland University College of Dublin School of Medicine and Department of CardiologyChildren's Health IrelandDublin D12 N512Ireland

BACKGROUND Isolated left ventricular apical hypoplasia(ILVAH),also known as truncated left ventricle(LV),is a very unusual *** is characterised by a truncated,spherical,and non-apex forming *** true apex is occupied by the right *** to the rarity of the disease,just a few case reports and limited case series have been published in the *** To analysing the so far 37 reported ILVAH cases *** The electronic databases PubMed and Scopus were investigated from their establishment up to December 13,*** The majority of cases reported occurred in males(52.7%).Mean age at diagnosis was 26.1±19.6 *** than a third of the patients were asymptomatic(35.1%).The most usual clinical presentation was breathlessness(40.5%).The most commonly detected electrocardiogram changes were T wave abnormalities(29.7%)and right axis deviation with poor R wave progression(24.3%).Atrial fibrillation/flutter was detected in 24.3%.Echocardiography was performed in 97.3%of cases and cardiac MRI in 91.9%of *** fraction was reduced in more than a half of patients(56.7%).An associated congenital heart disease was found in 16.2%.Heart failure therapy was administered in 35.1%of *** outcome was favorable in the vast majority of patients,with just one *** ILVAH is a multifaceted entity with a so far unpredictable course,ranging from benign until the elderly to sudden death during adolescence.

关键词： Isolated left ventricular apical hypoplasia Truncated left ventricle Electrocardiography Echocardiography cardiac magnetic resonance imaging Heart failure

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Tricuspid mass-curious case of Li-Fraumeni syndrome: A case report

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World Journal of Clinical Cases 2024年第11期12卷 1936-1939页

作者： Tyler Huffaker Stella Pak Anum Asif Prince Otchere Department of Cardiology University of Texas Health San AntonioSan AntonioTX 78701United States Department of Neurology Albany Medical CenterAlbanyNY 12208United States

BACKGROUND Li-Fraumeni syndrome(LFS)is a rare autosomal dominant cancer-predisposing syndrome,which can manifest as a polymorphic spectrum of *** is associated with an early onset in life,with the majority of cases occurring prior to the age of *** the infrequency of primary cardiac tumors,it behooves clinicians to remain vigilant in considering the differential diagnosis of such tumors in LFS patients who present with a cardiac *** is due to the markedly elevated risk for malignancy in this particular population,far surpassing that of the general *** SUMMARY Herein,we present a case of a 30-year-old female with LFS who was found to have a tricuspid valve leaflet *** This case exemplifies valuable learning points in the diagnostic approach for this exceptionally rare patient population.

关键词： Li-Fraumeni syndrome cardiac mass Intracardiac thrombus Transesophageal echocardiogram cardiac magnetic resonance imaging Case report

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Hypertrophic cardiomyopathy secondary to deficiency in lysosomeassociated membrane protein-2: A case report

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World Journal of Cardiology 2023年第11期15卷 609-614页

作者： Ye-Tong Zhao Xiu-Qun Cao Xiao-Lin Mu Department of Radiology Central Hospital of Dalian University of TechnologyDalian 116033Liaoning ProvinceChina Graduate School Dalian Medical UniversityDalian 116000Liaoning ProvinceChina Departments of Ultrasound and Health Medicine Central Hospital of Dalian University of TechnologyDalian 116033Liaoning ProvinceChina

BACKGROUND Danon disease(DD),in which mutations in the X-linked lysosome-associated membrane protein-2(LAMP-2)gene result in hypertrophic cardiomyopathy,is a rare disease,reported primarily in small samples or ***,with the development of cardiac magnetic resonance imaging and genetic technology in recent years,the number of reports has *** SUMMARY We report a case of DD in an adolescent male patient,confirmed by genetic *** patient was admitted to our hospital with complaints of a three-year history of chest tightness and shortness of *** preliminary clinical diagnosis is hypertrophic *** report includes the patient’s clinical course from hospital admission to death,step-by-step diagnosis,treatment course,and noninvasive imaging *** highlight how a noninvasive diagnostic approach,based solely on clinical and imaging“red flags”for DD,can be used to achieve a diagnosis of DD with a high degree of *** DD is a very dangerous cardiomyopathy,and it is necessary to achieve early diagnosis and treatment.

关键词： Danon disease Lysosome-associated membrane protein-2 gene Cardiomyopathy Hypertrophy cardiac magnetic resonance imaging Myocardial strain Case report

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