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World Journal of Clinical Cases 2024年第3期12卷 616-622页

作者： Xue-Min Zhu Chun-Xia Dong Lei Xie Hao-Xin Liu Huai-Qiang Hu School of Clinical Medicine Weifang Medical UniversityWeifang 261053Shandong ProvinceChina Department of Neurology the 960th Hospital of People′s Liberation ArmyJinan 250031Shandong ProvinceChina

BACKGROUND brain abscess is a serious and potentially fatal disease caused primarily by microbial *** progress has been made in the diagnosis and treatment of brain abscesses,the diagnostic timeliness of pathogens needs to be *** SUMMARY We report the case of a 54-year-old male with a brain abscess caused by oral *** patient recovered well after receiving a combination of metagenomic next-generation sequencing(mNGS)-assisted guided medication and *** Therefore,mNGS may be widely applied to identify the pathogenic microor-ganisms of brain abscesses and guide precision medicine.

关键词： brain abscess Metagenomic next-generation sequencing Periodontitis Oral bacteria Precision medicine Case report

Isolated cerebral mucormycosis that looks like stroke and brain abscess:A case report and review of the literature

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World Journal of Clinical Cases 2023年第7期11卷 1560-1568页

作者： Cai-Hong Chen Jing-Nan Chen Hang-Gen Du Dong-Liang Guo Department of Neurology Hangzhou Ninth People's HospitalHangzhou 311225Zhejiang ProvinceChina Department of Neurosurgery The Second Affiliated Hospital of Zhejiang University of Traditional Chinese MedicineHangzhou 310005Zhejiang ProvinceChina

BACKGROUND Cerebral mucormycosis is an infectious disease of the brain caused by fungi of the order *** infections are rarely encountered in clinical practice and are often misdiagnosed as cerebral infarction or brain *** mortality due to cerebral mucormycosis is closely related to delayed diagnosis and treatment,both of which present unique challenges for *** SUMMARY Cerebral mucormycosis is generally secondary to sinus disease or other disseminated ***,in this retrospective study,we report and analyze a case of isolated cerebral *** The constellation of symptoms including headaches,fever,hemiplegia,and changes in mental status taken together with clinical findings of cerebral infarction and brain abscess should raise the possibility of a brain fungal *** diagnosis and prompt initiation of antifungal therapy along with surgery can improve patient survival.

关键词： Cerebral mucormycosis Stroke brain abscess Diagnosis Treatment Case report

Cerebral syphilitic gumma misdiagnosed as brain abscess: A case report

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World Journal of Clinical Cases 2024年第3期12卷 650-656页

作者： Li-Kun Mu Li-Feng Cheng Jing Ye Meng-Yan Zhao Jin-Long Wang Department of Neurosurgery Shengli Oilfield Central HospitalDongying 257099Shandong ProvinceChina

BACKGROUND Cerebral syphilitic gumma is a relatively rare clinical *** clinical manifest-ations are non-specific,and the imaging manifestations are similar to other in-tracranial occupying lesions,often misdiagnosed as tumors or *** are few reports on this disease in the relevant *** our knowledge,we have reported the first case of cerebral syphilitic gumma misdiagnosed as a brain *** report this case and provide useful information for clinical doctors on neurosyphilis *** SUMMARY We report the case to explore the diagnostic essentials of cerebral syphilitic gumma and attempt to mitigate the rates of misdiagnosis and missed diagnosis by equipping physicians with knowledge of neurosyphilis *** cli-nical diagnosis and treatment of a patient with cerebral syphilitic gumma were *** manifestations,classifications,and diagnostic points were retro-spectively *** patient was admitted to the hospital with fever and limb *** magnetic resonance imaging showed multiple space-occupying lesions and a positive serum Treponema pallidum gelatin agglutination *** patient was misdiagnosed as having a brain abscess and underwent a craniotomy.A postoperative pathological diagnosis of syphilis gumma was *** patient improved and was discharged after penicillin anti-syphilis ***-up recovery was *** Cerebral syphilitic gumma is rare in clinical practice,and it is often misdiagnosed and *** diagnosis should be considered in combination with multiple examinations.

关键词： Neurosyphilis Cerebral syphilitic gumma brain abscess Misdiagnosis Treatment Case report

Rare case of cryptogenic brain abscess caused by Raoultella ornithinolityca

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World Journal of Clinical Cases 2017年第7期5卷 299-302页

作者： Marianna Luongo Department of Neurosurgery San Carlo Hospital

Cerebral abscess is a potentially fatal neurosurgical condition,despite improvements in technology,new antimicrobial agents and modern neurosurgical instruments and techniques.I report the case of a 64-yearold woman,affected by a right frontobasal brain abscess,compressing the homolateral frontal horn of lateral ventricle,with a second mass partially occupying the right orbital *** presented also with inflammatory sinusopathy involving the right maxillary,ethmoid and frontal *** 14 d of clinical observation and antimicrobial therapy,the patient received a computed tomography scan,which showed growth of the cerebral mass,with a ring of peripheral contrast enhancement and surrounding *** promptly underwent neurosurgical treatment and recovered well,except for the sight in her right eye,which remained compromised,as before the *** is believed to be the first case of cryptogenic cerebral abscess caused by Raoultella ornithinolityca isolated from the brain,with more than 1-year follow-up.

关键词： brain abscess Headache Raoultel a ornithinolityca Visual loss

brain abscess Caused by Bacillus megaterium in an Adult Patient

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Chinese Medical Journal 2015年第11期128卷 1552-1554页

作者： Fu-Ping Guo Hong-Wei Fan Zheng-Yin Liu Qi-Wei Yang Yi-Jia Li Tai-Sheng Li Department of Infectious Disease Peking Union Medical College Hospital Chinese Academy of Medical Sciences Beijing 100730 China Department of Laboratory Medicine Peking Union Medical College Hospital Chinese Academy of Medical Sciences Beijing 100730 China

Bacillus megaterium, a Gram-positive, aerobic, spore-forming, rod-shaped bacterium, has been found in widely diverse habitats and has been widely used as a source of recombinant protein in the industry. With a cell le... 详细信息

关键词： Bacillus Megaterium Infection brain abscess

brain abscess:surgical experiences of 162 cases

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Neuroimmunology and Neuroinflammation 2015年第1期2卷 153-161页

作者： Forhad Hossain Chowdhury Md Raziul Haque Mainul Haque Sarkar S.M.Noman Khaled Chowdhury Zahed Hossain Shisir Ranjan Department of Neurosurgery National Institute of Neurosciences and HospitalSher-e-Bangla NagarDhaka 1207Bangladesh Department of Neurosurgery Dhaka Medical CollegeDhaka 1000Bangladesh Department of Neonatolgy Dhaka Medical CollegeDhaka 1000Bangladesh

Aim:brain abscess still poses a public health challenge in spite of the advent of modern neurosurgical techniques and ***,we present our surgical experiences and ultimate outcome in the management of brain ***:Totally,162 patients with proved brain abscess who underwent surgical treatment were included in this *** prospectively recorded data of surgical management of brain abscess and the ultimate outcome(by Glasgow outcome scale)were studied ***:Total number of cases was 162,of which 113 were acute pyogenic abscess while 49 were chronic *** the chronic abscess,29 were chronic pyogenic abscess,14 were tubercular,3 aspergillus,and 3 abscesses were in malignant brain *** acute cases,common clinical features were headache,fever,vomiting,focal deficit and *** chronic abscesses,common clinical features were mild to moderate headache and progressive focal ***-three(45.06%)patients had adjacent localized sinus,middle ear or cranial *** common predisposing factors included postneurosurgery,postpenetrating injury to brain,chronic suppurative otitis media,and congenital heart disease,infective endocarditis,sinusitis and sub optimum *** lobe involved in 30.2%cases,temporal lobe is next to *** time burr hole aspiration in 111(68.5%)cases,two or more times burr hole aspiration were done in 34(21%)*** culture was negative in 129(79.62%)*** number of death was 22(13.58%)*** resolution of abscess with complete recovery of preoperative neuro-deficit was seen in 80.86%cases and recovery with major neuro-deficit was observed in 5.55%*** is a significant association between Glasgow coma scale(GCS)on admission and mortality in brain ***:In most of the cases,pus culture did not yield growth of any causative *** was not directly related to surgical intervention,but GCS on admission has a significant

关键词： Acute and chronic brain abscess brain abscess outcome surgical management

brain abscess after COVID-19: Case Report

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Advances in Infectious Diseases 2023年第1期13卷 77-80页

作者： Natalia Chilinque Zambão da Silva Patrícia Yvonne Maciel Pinheiro Joao Gabriel Dib Farinhas Luiz Eduardo Dalmeida Machado Sampaio Fluminense Federal University Rio de Janeiro Brazil Antonio Pedro University Hospital Fluminense Federal University Rio de Janeiro Brazil Pasteur Hospital Rio de Janeiro Brazil

As the COVID-19 pandemic progresses, complications and unusual presentations of the disease have been described. Among them, the involvement of distinct parts of the neuroaxis. We report a rare case of brain abscess in elderly after SARS-Cov-2 infection readmitted in our health unit. Patient was treated with ceftriaxone, metronidazole and vancomycin with good clinical and therapeutic response. The satisfactory conduct of the case was only possible by the involvement of a multiprofessional team, which sought early diagnosis, surgical intervention and adequate duration of treatment.

关键词： brain abscess Biopsy COVID-19

Neonatal brain abscess:Case Report of 12 Cases and Literature Review

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Journal of Clinical and Nursing Research 2022年第6期6卷 97-104页

作者： Nan Peng Zhen Chen Qi Lu Department of Neonatology Children’s Hospital of Chongqing Medical UniversityNational Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChina International Science and Technology Cooperation Base of Child Development and Critical DisordersChongqing Key Laboratory of Child Infection and ImmunityChongqingChina

Objective:To investigate the etiological characteristics,clinical manifestations,and early identification methods of neonatal brain ***:The baseline characteristics,clinical manifestations,and laboratory results of 12 neonatal brain abscess cases were retrospectively ***:The clinical manifestations were fever,convulsion,and lethargy.A small number of them had respiratory and circulatory *** diagnosis made was based on imaging *** 12 cases were confirmed by cranial enhanced computed tomography(CT)or magnetic resonance imaging(MRI).Blood cultures of 9 cases were positive,with Escherichia coli in 6 cases,β-hemolytic Streptococcus in 1 case,methicillin-resistant Staphylococcus aureus in 1 case,and Enterococcus faecium in 1 ***,only 3 of them had positive cerebrospinal fluid(CSF)*** the 12 neonates were treated with antibiotic therapy upon admission,with only 3 cases treated with *** them,4 recovered and were discharged,while the remaining 8 discontinued their ***:Escherichia coli is the most common pathogen of neonatal brain abscess in our *** clinical manifestations of neonatal brain abscess are atypical,and the prognosis is *** and circulatory failure in children with intracranial infection may indicate the presence of brain *** children with suspected brain abscess,cranial enhanced CT or MRI should be performed as soon as possible to make an early *** prevention of brain abscess should be prioritized;neonates with sepsis or meningitis should receive prompt and strong antibiotic therapy in an effort to prevent the development of brain abscess.

关键词： brain abscess Clinical manifestations Enhanced CT or MRI Antibiotic

Perioperative Nursing of a Case of Right Temporal Lobe brain abscess Ruptured into the Ventricle

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Journal of Cancer Therapy 2021年第5期12卷 233-239页

作者： Xiaoqun Chen Shuo Yang Qinqin Zhao Zhihuan Zhou Department of Neurosurgery Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Guangzhou China

Objective: To explore the perioperative nursing method of brain abscess breaking into the ventricle. Methods: By reviewing the clinical data of 1 case of right temporal lobe brain abscess into the ventricle, the effective nursing methods were summarized. Results: The patient’s condition was advanced quickly, and the diagnosis was treated in time to avoid brain hernia, but the treatment was difficult because of the critical condition. Conclusion: Brain abscess is a very serious intracranial infectious disease. It is of great significance to observe the changes in patients’ condition and take effective nursing measures.

关键词： brain abscess Ventricle Perioperative Nursing

Neuronavigation combined with nerve electrophysiology in excision of brain abscess: A case report and literature review

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Translational Neuroscience and Clinics 2017年第4期3卷 224-228页

作者： Xiaoxu Shen Dong Zhao Qi Liu Department of Neurosurgery Shihezi University First Affiliated Hospital

A brain abscess is a parenchymal infection,which is a severe intracranial infectious disease. Although the incidence is low,it causes serious inflammation and neurological deficits. The current treatments for brain abscesses are primarily surgical,including abscess resection or puncture and drainage. In recent years,extensive application of neuronavigation and electrophysiological monitoring technology have improved the safety and reliability of neurosurgery. To explore the application and curative effect of neuronavigation combined with neurophysiological techniques in the treatment of brain abscesses,we retrospectively analyzed a female patient who had undergone neurological monitoring and neuronavigation-assisted surgery to remove an abscess in 2015. Diagnosis and treatment are reported.

关键词： neuronavigation nerve electrophysiology brain abscess parenchymal disease intracranial