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DEGRADATION AND PROCESSING OF PLA AND ITS APPLICATION IN fixation OF bone fracture

Chinese Journal of Reactive Polymers 1999年第1期8卷 102-109页

作者： HU Yushan BAI Dongren ZHANG Zhengpu WANG Yongmei HE Binglin State Key Laboratory of Functional Polymeric Materials for Adsorption and Separation Institute of Polymer Chemistry Nankai UniversityTianjin 300071 Department of Chemistry Nankai UniversityTianjin 300071

PLA is presently considered as the most attractive compound for temporarytherapeutic application in the biomedical field. In this paper we give an overview of thepresent knowledge on the degradation behavior,processin... 详细信息

关键词： PLA Degradation Processing bone fracture fixation Review

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PREPARATION AND PROPERTIES OF HIGH STRENGTH RODS FROM L-AND D,L-LACTIDE COPOLYMER

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Chinese Journal of Polymer Science 2001年第4期19卷 351-357页

作者： Yu-shan Hu Zheng-pu Zhang Dong Song Dong-ren Bai Yong-mei Wang Institute of Polymer Chemistry State Key Laboratory of Functional Polymeric Materials for Adsorption and Separation, Nankai University Tianjin 300071, China Institute of Polymer Chemistry Stt. Key Lab. Funct. Polymeric M. Nankai University Tianjin 300071 China

Starling with the L- and D,L-lactide copolymer (L:DL = 9:1) [P(L-DL)LA] of M-W = 32.1 x 10(4), rods were obtained through a two stage process: (1) melt-extrusion at 155 degreesC, and (2) hot-drawing at 90 degreesC to various drawing ratios. The molecular weight of P(L-DL)LA fell to 9.3 x 10(4) as a consequence of the production process. The crystallization and molecular orientation of P(L-DL)LA developed as a result of the hot-drawing. The mechanical strengths of the rods increase with the drawing ratio; The maximum for tensile strength, bending strength, bending modulus, and shear strength are 329 MPa, 237 MPa, 8.8 GPa, and 157 MPa, respectively.

关键词： P(L-DL)LA self-reinforcement rod process bone fracture fixation

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External fixation versus open reduction and internal fixation for tibial pilon fractures： A meta-analysis based on observational studies

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Chinese Journal of Traumatology 2016年第5期19卷 278-282页

作者： Yi-Chen Meng Xu-Hui Zhou Department of Orthopedics Changzheng Hospital Second Affiliated Hospital of Second Military Medical University Shanghai China

Purpose： Tibial pilon fractures remain challenging for an orthopaedic surgeon to repair. External fixation （ExFix） and open reduction and internal fixation （ORIF） are two widely used methods for repairing tibial pilon fractures. However, conclusions of comparative studies regarding which method is superior are controversial. Our aim is to compare ORIF and ExFix and clarify which method is better in terms of reduction and union results and major complications. Methods： A computerized research of MEDLINE, EMBASE, Springer, and Cochrane Library （before December 2014） for studies of any design comparing ORIF and ExFix was conducted. Weighted mean difference （WMD）, risk ratio （RR） and corresponding 95% confidence intervals （Cl） were used for esti- mating the effects of the two methods. Statistical analyses were done using Review Manager Version 5.2. Results： Ten cohort studies and one randomized clinical trial were included in our ultimate analysis. And the analysis found no significant difference between the two methods in deep infection （p = 0.13）, reduction （p = 0.11）, clinical evaluation （p = 0.82）, post-traumatic arthrosis Cp = 0.87）, and union time （p = 0.35）. Besides, ExFix group was found to have a higher rate of superficial infection （p = 0.001）, malunion （p = 0.01） and nonunion （p= 0.02）, but have a lower risk of unplanned hardware removal （p = 0.0002）. Conclusions： We suggest that ORIF has a relatively lower incidence rate of superficial infection, malunion and nonunion, hut a higher rate of unplanned hardware removal. No difference was found in deep infection, reduction, clinical evaluation. ~ost-traumatic arthrosis and union time.

关键词： fractures bone fracture fixation internal External fixation Meta-analysis

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