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Towards prenatal biomonitoring in Nanjing, China： lead and cadmium levels in the duration of pregnancy

Chinese Medical Journal 2013年第16期126卷 3107-3111页

作者： LIU Kang-sheng MAO Xiao-dong HAO Jia-hu SHI Juan DAI Chun-fang CHEN Wen-jun Department of Clinical Laboratory State Key Laboratory ofReproductive Medicine Nanjing Matemity and Child Health CareHospital Affiliated to Nanjing Medical University Nanjing Jiangsu210029 China Department of Endocrine Jiangsu Province Academy of TraditionalChinese Medicine Nanjing Jiangsu 210028 China Department of Nutrition and Food Hygiene School of Public Healthof Anhui Medical University Hefei Anhui 230032 China Department of Maternity and Child Health Care Nanjing Maternity and Child Health CareHospital Nanjing Jiangsu 210004 China Departmentof Obstetrics Nanjing Maternity and Child Health CareHospital Nanjing Jiangsu 210004 China

Background Prenatal lead and cadmium exposure will not only influence the mother＇s organ systems,but also will provide an environment that may influence the fetus and neonate in a harmful *** the present study,we detected the blood lead levels （BLLS） and cadmium levels for the duration of pregnancy and 6-12 weeks after delivery and to analyze the influencing factors of BLLs in healthy pregnant *** A cohort study survey was carried *** recruited 174 healthy pregnant women without pregnancy or obstetric complications or abnormal pregnancy outcomes as the gravida group,and 120 healthy non-pregnant women as the control *** The lead concentrations in the three pregnancy trimesters and in the postpartum period were：（5.98±2.43）,（5.54±2.01）,（5.59±1.97）,and （6.76±1.74） μg/dl; and （6.75±2.13） μg/dl in the control *** cadmium concentrations in the three pregnancy trimesters and postpartum period were 1.61±0.45,1.63±0.46,1.64±0.49,and 1.67±*** found that the BLLs in the gravida group were lower than in the control group during all three ***,supplement nutritional elements （dietary supplements and nutritional （food） elements）,and the time of house painting could affect BLLs in pregnant ***-related occupations,using cosmetics,and living in a house painted more recently than one year previously are risk factors of high BLLs among pregnant women,while calcium,iron,zinc,and milk supplements are protective *** These findings may help people,especially pregnant women,to reduce lead exposure via supplements of calcium,iron,zinc,and milk or avoiding contacting risk factors.

关键词： blood lead levels blood cadmium levels pregnancy lead exposure

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