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The appliances and prospects of aurum nanomaterials in biodiagnostics, imaging, drug delivery and combination therapy

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Asian Journal of Pharmaceutical Sciences 2019年第4期14卷 349-364页

作者： Dan Yang Feiyang Deng Dechun Liu Bo He Bing He Xing Tang Qiang Zhang School of Pharmacy Shenyang Pharmaceutical UniversityShenyang 110016China Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems School of Pharmaceutical SciencesPeking UniversityBeijing 100191China State Key Laboratory of Natural and Biomimetic Drugs Peking UniversityBeijing 100191China

Aurum nanomaterials(ANM), combining the features of nanotechnology and metal elements, have demonstrated enormous potential and aroused great attention on biomedical applications over the past few decades. Particularly, their advantages, such as controllable particle size, flexible surface modification, higher drug loading, good stability and biocompatibility, especially unique optical properties, promote the development of ANM in biomedical field. In this review, we will discuss the advanced preparation process of ANM and summarize their recent applications as well as their prospects in diagnosis and therapy. Besides, multi-functional ANM-based theranostic nanosystems will be introduced in details, including radiotherapy(RT), photothermal therapy(PTT), photodynamic therapy(PDT), immunotherapy(IT), and so on.

关键词： Gold nanomaterials Imaging and biodiagnostics Drug delivery Photothermal therapy Immunotherapy Combination therapy

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Optical Sensing： the Last Frontier for Enabling Intelligence in Our Wired up World and Beyond

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Photonic Sensors 2012年第3期2卷 193-202页

作者： John CANNING Interdisciplinary Photonics Laboratories (iPL) School of Chemistry 222 Madsen Building F09 The University ofSydney NSW 2006 Australia

Consigned to the shadows of telecommunications, optical sensing has often taken a back seat in a young person＇s mind when considering the importance of photonics, or optics, to the advancement of the society and of knowledge. Here, I touch on briefly how broad optical sensing and sensing generally has become and how and why it is becoming the catalyst for the convergence of many technologies and in the process raising significant philosophical questions about the transformation of our society and indeed ourselves. In doing so I touch on many of the complexities in real life that influence the breakthroughs we see today, including a healthy speculation and critique on our society and an awareness of the motivations to improve it that drive many of them.

关键词： Optical sensors galactic village global village wireless smartphones science fiction energy medical biodiagnostics education students optical fiber

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