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Associations among benign prostate hypertrophy, atypical adenomatous hyperplasia and latent carcinoma of the prostate

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Asian Journal of Andrology 2007年第2期9卷 229-233页

作者： Konstantinos Stamatiou Alevizos Alevizos Mohamed Natzar Constantinos Mihas Anargiros Mariolis Emmanouel Michalodimitrakis Fragiskos Sofras Department of Urology University Hospital Medical School University of Crete Heraklion 71110 Greece Department of Urology Tzaneion General Hospital Piraeus18536 Greece Department of Medical Research Health Center of Vyronas Athens 16231 Greece Department of Forensic Sciences University Hospital Medical School University of Crete Heraklion 71110 Greece

Aim： To investigate the frequency of atypical adenomatous hyperplasia （AAH） and its associations with benign prostate hypertrophy （BPH） and latent histological carcinoma of the prostate （LPC） in autopsy material. Methods： Two hundred and twelve prostate specimens obtained from autopsy material were subjected to whole mount analysis in an attempt to investigate the associations among BPH, AAH and LPC. Results： Most histological carcinomas and AAH lesions were found in enlarged prostates with intense hypertrophy. No statistically significant relation was found between BPH and the main characteristics of LPC, such as tumor volume, histological differentiation and biological behavior. Our data regarding multi-focal tumors showed a tendency for multi-focal carcinomas to develop in larger prostates, and a tendency of AAH lesions to develop in larger prostates. No statistically significant relation was found between AAH and LPC. Conclusion： There seems not any causative aetiopathogenetical or topographical relation between AAH lesions and prostate adenocarcinoma. AAH lesion seems to be a well-defined mimicker of prostatic adenocarcinoma, and the reported association of AAH with prostatic carcinoma could probably be an epiphenomenon.

关键词： atypical adenomatous hyperplasia histological prostate cancer benign prostate hypertrophy

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Correlation between the International prostate Symptom Score, Ultrasound Features and Maximum Flow Rate in Cameroonian Patients with benign Prostatic hypertrophy

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Open Journal of Urology 2022年第1期12卷 37-50页

作者： Landry Oriole Mbouché Achille Aurèle Mbassi Frantz Guy Epoupa Ngallè Forbang Ako Axel Stéphane Nwaha Makon Boniface Moifo Fru Angwafo III Department of Surgery and Specialities Faculty of Medicine and Biomedical Sciences Yaoundé Cameroon Yaoundé Gyneco-Obstetric and Pediatric Hospital Yaoundé Cameroon Department of Surgery Higher Institute of Medical Technology Yaoundé Cameroon Department of Radiology and Medical Imaging Faculty of Medicine and Biomedical Sciences Yaoundé Cameroon

Background: benign prostatic hypertrophy is the non-malignant stromal and epithelial proliferation of the prostate gland, with or without associated anatomical enlargement of the gland and clinical symptoms. Symptomatic benign prostatic hypertrophy may cause obstructive symptoms, irritative symptoms or both obstructive symptoms include a sensation of incomplete bladder emptying, straining to void, urinary hesitancy and weak stream while irritative symptoms include dysuria, nocturia, urinary frequency and urinary urgency. A quantitative measure of the severity of lower urinary tract symptoms due to benign prostatic hypertrophy can be obtained using the International prostate Symptoms Score. Ultrasonography is useful for helping to determine bladder and prostate size in patients with urinary lower urinary tract symptoms. Uroflowmetry is a non-invasive test that assesses voiding function. It provides valuable data on the voided volume, time is taken to reach maximum flow rate and average flow rate. The goal of this study was to improve the follow up of patients with benign prostatic hypertrophy by providing simple, available, affordable and non-invasive that best predict bladder outlet obstruction and the quality of life in these patients. Method: This was a cross-sectional analytic study carried out over a period of five months from May 2020 to September 2020 at the Yaounde Gynaeco-Obstetric and Paediatric Hospital, which is a tertiary hospital in Cameroon. Were included in the study, adult males who presented with lower urinary tract symptoms and prostatic enlargement suggestive of benign prostatic hypertrophy taking into account clinical, uroflowmetry and ultrasound findings. Results: A study population of 103 participants was recruited. The mean age of patients was 63.17 ± 10.26 years. Concerning the International prostate Symptoms Score, the mean total, voiding (obstructive) and storage (irritative) scores were 14

关键词： benign prostate hypertrophy Intravesical Prostatic Protrusion Acute Urinary Retention

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