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Hepatobiliary & Pancreatic diseases International 2012年第3期11卷 262-266页

作者： Gen-Shu Wang, Yang Yang, Hua Li, Nan Jiang, Bin-Sheng Fu, Hai Jin, Jian-Xu Yang and Gui-Hua Chen Department of Hepatic Surgery and liver Transplant Center, Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China Department of Hepatic Surgery and liver Transplant Center Third Affiliated Hospital Sun Yat-Sen University Guangzhou 510630 China

BACKGROUND: Few studies have been performed to assess health-related quality of life (HRQOL) in liver transplantation (LT) patients in the mainland of China. This study aimed to investigate the HRQOL of post-LT patients in a single center. METHODS: HRQOL was evaluated by the SF-36 (Chinese version) questionnaire in 60 patients (LT group) who had received LT for benign end-stage liver disease (BELD). Fifty-five patients with BELD (BELD group) and 50 healthy volunteers from the general population (GP group) were also evaluated, and the results were compared among the three groups. RESULTS: There was a significant difference among the three groups in terms of the scores of eight domains in the SF-36 (P0.025), but higher scores for the remaining seven domains (P0.025), but had lower scores for the remaining three domains (P<0.025). Lower family income was found to be associated with reduced physical function and mental health scores (P<0.05). Better education was associated with increased mental health scores (P<0.05). CONCLUSIONS: LT patients generally have a good HRQOL although some respects of their HRQOL remains to be improved. Lower family income and poor education are important factors relating to the poor HRQOL of LT patients.

关键词： health-related quality of life liver transplantation benign end-stage liver disease

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