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A prospective study to evaluate the efficacy of an intracardiac electrogram-based atrioventricular and interventricular intervals optimization method in cardiac resynchronization therapy

引用

Chinese Medical Journal 2012年第3期125卷 428-433页

作者： Hua Wei Wang Dong-mei Cai Lin Sun Chao-feng Fu Guo-sheng Wang Yu-tang Yan Ji Luo Zhi-ling Xu Jing Wang Zhi-yong Xu Geng Shen Fa-rong Xu Wei Wang Jing-feng Ren Xue-jun Jin Wei Zhang, Nan Lau, Elizabeth Oi-Yan Zhang Shu Peking Union Med Coll Dept Cardiol Cardiovasc Inst Beijing 100037 Peoples R China Chinese Acad Med Sci Dept Cardiol Cardiovasc Inst Beijing 100037 Peoples R China Chinese Acad Med Sci Fuwai Hosp Beijing 100037 Peoples R China Shenyang No Hosp Dept Cardiol Shenyang 110000 Liaoning Peoples R China Chongqing Med Univ Dept Cardiol Peoples Hosp Chengdu 3 Med Coll Chengdu 2 Chengdu 610031 Sichuan Peoples R China Xi An Jiao Tong Univ Coll Med Dept Cardiol Affiliated Hosp 1 Xian 710061 Shaanxi Peoples R China Zhejiang Univ Sch Med Dept Cardiol Sir Run Run Shaw Hosp Hangzhou 310016 Zhejiang Peoples R China Chinese Peoples Liberat Army Gen Hosp Dept Cardiol Beijing 100853 Peoples R China Anhui Prov Hosp Dept Cardiol Hefei 230001 Anhui Peoples R China Kunming Med Coll Dept Cardiol Affiliated Hosp 1 Kunming 650032 Yunnan Peoples R China Tianjin Chest Hosp Dept Cardiol Tianjin 300051 Peoples R China Inner Mongolian Peoples Hosp Dept Cardiol Hohhot 010017 Inner Mongolia Mongol Peo Rep Zhejiang Univ Sch Med Dept Cardiol Affiliated Hosp 2 Hangzhou 310009 Zhejiang Peoples R China Zhejiang Hosp Dept Cardiol Hangzhou 310030 Zhejiang Peoples R China Nanjing Univ Sch Med Dept Cardiol Affiliated Drum Tower Hosp Nanjing 210008 Jiangsu Peoples R China Sun Yat Sen Univ Dept Cardiol Sun Yat Sun Mem Hosp Guangzhou 510120 Guangdong Peoples R China Capital Med Univ Dept Cardiol Beijing Anzhen Hosp Beijing 100029 Peoples R China Beijing Inst Heart Lung & Blood Vessel Dis Beijing 100029 Peoples R China Shanghai Jiao Tong Univ Sch Med Dept Cardiol Shanghai Peoples Hosp 1 Shanghai 200080 Peoples R China

Background Cardiac resynchronization therapy （CRT） with biventricular pacing improves cardiac function,functional capacity and quality of life in selected patients with heart *** current study aimed to evaluate the efficacy of the intracardiac electrogram （IEGM）-based optimization method,QuickOptTM,in Chinese patients treated with *** Aortic time velocity integrals （AVTI） achieved at the sensed atrioventricular （AV）,paced AV and interventricular （VV） interval settings recommended by both QuickOptTM and standard echocardiographic optimization were measured in 101 *** and the strength of the relationship between the two timing cycle optimization methods were assessed by intra-class correlation coefficient （ICC）.Results The ICC showed good agreement and correlation with what the AVTI achieved at the optimal sensed AV （ICC=0.9683 （0.9535-0.9785））,paced AV （ICC=0.9642 （0.9475-0.9757）） and VV （ICC=0.9730 （0.9602-0.9817）） interval settings determined by the two optimization *** average time required by echocardiographic optimization and by QuickOptTM were （78.32±32.40） minutes and （1.98±1.64） minutes respectively （P 〈0.0001）.Conclusion The QuickOptTM algorithm provides a quicker,simpler and reliable alternative to the standard method for timing cycle optimization.（*** Reference Number：NCT00918294）

关键词： heart failure cardiac resynchronization therapy atrioventricular interval interventricular interval timing cycle optimization echocardiography aortic velocity time integral intracardiac electrogram QuickOptTM

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