检索结果-南通市图书馆

Prevention and management of post-instability glenohumeral arthropathy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2017年第3期8卷 229-241页

作者： Brian R Waterman Kelly G Kilcoyne Stephen A Parada Josef K Eichinger Department of Orthopaedic Surgery and Rehabilitation William Beaumont Army Medical Center Eisenhower Army Medical Center Madigan Army Medical Center

Post-instability arthropathy may commonly develop in high-risk patients with a history of recurrent glenohumeral instability,both with and without surgical *** related to anterior shoulder instability,the incidence and rates of arthritic progression may vary *** arthritic changes may be present in up to two-thirds of patients after primary Bankart repair and 30%after Latarjet procedure,with increasing rates associated with recurrent dislocation history,prominent implant position,non-anatomic reconstruction,and/or lateralized bone graft ***,the presence radiographic arthrosis does not predict poor patient-reported *** exhausting conservative measures,both joint-preserving and arthroplasty surgical options may be considered depending on a combination of patient-specific and anatomic *** procedures are optimally indicated for individuals with focal disease and may yield superior symptomatic relief when combined with treatment of combined shoulder *** more advanced secondary arthropathy,total shoulder arthroplasty remains the most reliable option,although the clinical outcomes,wear characteristics,and implant survivorship remains a concern among active,young patients.

关键词： arthropathy Glenohumeral Dislocation Latarjet Instability

Rotator Cuff Reconstruction and Humeral Head Replacement Using Smaller Humeral Prostheses in Cuff Tear arthropathy Patients under 70 Years of Age

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Orthopedics 2014年第10期4卷 263-272页

作者： Naoki Miyoshi Naoki Suenaga Naomi Oizumi Noboru Taniguchi Hiroshi Ito Department of Orthopaedic Surgery Asahikawa Medical University Asahikawa Japan The Upper Extremity Center of Joint Replacement and Endoscopic Surgery Hokushin Hospital Sapporo Japan Department of Orthopaedic Surgery Miyazaki University Miyazaki Japan

Background: Most reverse shoulder arthroplasty (RSA) studies have shown good improvement in arm elevation without improvements in external rotation (ER). In addition, high rates of complications after long-term RSA have been reported, suggesting that RSA should be limited to elderly patients, especially those who are older than 70 years old. Since 2001, we have developed a strategy of rotator cuff reconstruction with muscle transfer and humeral head replacement (HHR), using smaller humeral prostheses, in cuff tear arthropathy patients. The aim of the present study was to investigate the clinical outcome of our strategy in patients under 70 years of age who had irreparable rotator cuff tears and osteoarthritis. Materials and Methods: A total of 25 shoulders of 25 patients under 70 years of age (males, 15;females, 10) with irreparable cuff tears were treated with HHR and cuff reconstruction. The average age at the time of surgery was 64.3 years (range, 55 - 69) and the average follow-up period was 38.7 months (range, 24 - 72). The cuff defect was repaired using a partial subscapularis transfer in 14 shoulders;nine shoulders required a latissimus dorsi transfer, one required a pectoralis major transfer, and one required both a latissimus dorsi and a pectoralis major transfer. Clinical outcomes were assessed with the range of motion (ROM), UCLA score, Japanese Orthopaedic Association (JOA) score and postsurgical complications. Results: Shoulder pain was diminished in all patients after surgery. The preoperative UCLA and JOA scores were 13.1 and 47.0 respectively, improving to 28.6 and 81.5 respectively after surgery. Active forward flexion has improved from an average of 89.0° to 138.8°, and the ER improved from an average of 16.2° to 33.2°. No complications occurred after surgery. Conclusion: Anatomical reconstruction using smaller head humeral prostheses yielded favorable results and less complication, compared with RSA. Considering another advantage of ability to ret

关键词： Irreparable Rotator Cuff Tear Cuff Reconstruction Cuff Tear arthropathy Humeral Head Replacement Using a Small Head

Neuropathic arthropathy of the shoulder: Two cases of syringomyelia with cocaine use

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Internal Medicine 2012年第1期2卷 27-30页

作者： Jerry A. Rubano Suleman Bhana Dodji Modjinou Colette R. J. Pameijer Heidi Roppelt Divisions of Surgical Oncology/Upper Gastrointestinal Surgery and Rheumatology Stony Brook University Hospital New York USA

Neuropathic arthropathy (NA) is a progressive, degenerative disorder associated with decreased sensory innervation of the involved joints. The shoulder joint is an uncommon presentation for NA, although syringomyelia is the most common cause for this joint. Two cases are presented of NA of the shoulder, with both patients having a history of syringomyelia and cocaine use. In both cases a work up for malignancy was negative, but imaging was consistent with NA. Although syringomyelia has been linked with this presentation in prior publications, the role of cocaine use may not be incidental, with complex biochemical interactions in bone metabolism. Cocaine has been shown to involve the Leptin, Neuromedin U (NmU), cocaine and amphetamine-regulated transcript (CART), and Receptor activator of nuclear factor kappa-B ligand (RANKL) pathways of bone remodeling. Treatment can be challenging, involving concurrent use of pharmacotherapy, surgical correction, and protective bracing.

关键词： Neuropathic arthropathy Charcot Syringomyelia Cocaine RANKL

Evaluation of Charcot Neuroarthropathy in Diabetic Foot Disease Patients at Tertiary Hospital

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Surgical Science 2016年第6期7卷 250-257页

作者： Ahmed M. A. Kensarah Nisar Haider Zaidi Abdulhaleem Noorwali Hager Aref Ahmed Mohammed Makki Afaf Ghunaim Wail Tashkandi Sara Mohammad Beayari Adel Johari Department of Surgery Faculty of Medicine King Abdulaziz University Hospital King Abdulaziz University Jeddah Saudi Arabia

Purpose: To evaluate Charcot neuroarthropathy in diabetic foot patients at tertiary hospital. Methods and Material: It is a retrospective study from 2005 to 2015 of Charcot foot patients in diabetic patients admitted in King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Sixty-four patients were admitted as diabetic foot disease and were studied by reviewing patients records of demography, pain, discharge, duration of disease, duration and types of diabetes IDDM [Insulin Dependant Diabetes Mellitus] NIDDM [Non Insulin Dependent Diabetes Mellitus], history of trauma, peripheral vascular disease, obesity, hypertension, co-morbid conditions, previous surgery, involvement of fore foot/midfoot/hindfoot, deformity, ulcer and treatment like casts, offloading devices, pharmacological like biphosphonates, debridement, osteotomy, arthrodesis, exostectomy, and amputation. Results: Majority of patients were males (81.2%). Mean age was 61.75 years. Pain was reported in 25% of patients, numbness in 12.5%, foot deformity in 23.4%, pus discharge in 73.4%, difficulty in walking in 12.5%, and 10.9% had history of trauma. Majority of patients were NIDDM 68.8%, IDDM 31.3%, (62.5% had DM more than 10 years and 36.9% had DM less than 10 years), controlled DM in 21.9% and uncontrolled DM in 73.4%, nephropathy in 46.3%, neuropathy in 59.4%, retinopathy in 40.6%, cardiomyopathy in 48.4% and vasculopathy in 56.3%. Charcot arthropathy was in 28.1% of cases and forefoot was involved in 65.5%, midfoot in 4.7% and hindfoot/ankle in 21.9%. It was forefoot which was mainly involved in Charcot joint disease. It was demonstrated by X-rays which showed subluxation in 40.6%, dislocation in 54.7%, disorganized foot joints in 42.2%, bone resorption in 23.4%, osteomyelitis in 14.1%, fractures in 50%, joint collapse in 39.1% and destruction of articular surfaces in 37.5%. Debridement was done in 25% of cases while 75% of patients underwent some sort of amputation. 14.1% of patients underwent above k

关键词： Charcots Diabetes arthropathy Diabetic Foot Prevalence

Bone marrow mononuclear cells for joint therapy: The role of macrophages in inflammation resolution and tissue repair

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Stem Cells 2021年第7期13卷 825-840页

作者： Bruno C Menarim James N MacLeod Linda A Dahlgren Gluck Equine Research Center Department of Veterinary ScienceCollege of AgricultureFood and EnvironmentUniversity of KentuckyLexingtonKY 40546United States Department of Large Animal Clinical Sciences Virginia-Maryland College of Veterinary MedicineVirginia TechBlacksburgVA 24060United States

Osteoarthritis(OA)is the most prevalent joint disease causing major disability and medical *** is a central feature of OA and is primarily driven by *** macrophages not only drive inflammation but also its resolution,through a coordinated,simultaneous expression of pro-and anti-inflammatory mechanisms that are essential to counteract damage and recover *** OA therapies are largely based on anti-inflammatory principles and therefore block pro-inflammatory mechanisms such as prostaglandin E2 and Nuclear factor-kappa B signaling ***,such mechanisms are also innately required for mounting a pro-resolving response,and their blockage often results in chronic low-grade *** minor injury,macrophages shield the damaged area and drive tissue *** the damage is more extensive,macrophages incite inflammation recruiting more macrophages from the bone marrow to maximize tissue repair and ultimately resolve ***,sustained damage and inflammation often overwhelms pro-resolving mechanisms of synovial macrophages leading to the chronic inflammation and related tissue degeneration observed in ***,experimental and clinical studies have shown that joint injection with autologous bone marrow mononuclear cells replenishes inflamed joints with macrophage and hematopoietic progenitors,enhancing mechanisms of inflammation resolution,providing remarkable and long-lasting *** creating an ideal environment for resolution with high concentrations of interleukin-10 and anabolic growth factors,macrophage progenitors also have a direct role in tissue *** constitute a large part of the early granulation tissue,and further transdifferentiate from myeloid into a mesenchymal *** cells,characterized as fibrocytes,are essential for repairing osteochondral ***“omics”studies focused on identifying key drivers of macrophagemediated resolution of j

关键词： Osteoarthritis arthropathy Synovitis Hematopoietic progenitor Homeostasis Cell therapy

Initial joint bleed volume in a delayed on-demand treatment setup correlates with subsequent synovial changes in hemophilic mice

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Animal Models and Experimental Medicine 2020年第2期3卷 160-168页

作者： Kare Kryger Vols Mads Kjelgaard-Hansen Carsten Dan Ley Axel Kornerup Hansen Maj Petersen Global Drug Discovery Novo Nordisk A/SMaaloevDenmark Veterinary and Animal Sciences University of CopenhagenFrederiksbergDenmark Veterinary Clinical Sciences University of CopenhagenFrederiksbergDenmark

Background: Hemophilic arthropathy is a debilitating morbidity of hemophilia caused by recurrent joint bleeds. We investigated if the joint bleed volume, before initiation of treatment, was linked to the subsequent degree of histopathological changes and the development of bone pathology in a mouse model of hemophilic ***: FVIII knock-out(F8-KO) mice were dosed with a micro-CT blood pool agent prior to induction of hemarthrosis. Eight hours after induction, the bleed volume was quantified with micro computed tomography(micro-CT) and recombinant FVIII treatment initiated. On Day 8, inflammation in the knees was characterized by fluorescence molecular tomography. On Day 14, knee pathology was characterized by micro-CT and histopathology. In a second study, contrast agent was injected into the knee of wild-type(WT) mice, followed by histopathological evaluation on Day ***: The average joint bleed volume before treatment was 3.9 mm3. The inflammation-related fluorescent intensities in the injured knees were significantly increased on Day 8. The injured knees had significantly increased synovitis scores, vessel counts, and areas of hemosiderin compared to un-injured knees. However, no cartilage-or bone pathology was observed. The bleed volume before initiation of treatment correlated with the degree of synovitis and was associated with high fluorescent intensity on Day 8. In F8-KO and WT mice, persistence of contrast agent in the joint elicited morphological ***: When applying a delayed on-demand treatment regimen to hemophilic mice subjected to an induced knee hemarthrosis, the degree of histopathological changes on Day 14 reflected the bleed volume prior to initiation of treatment.

关键词： Animal models arthropathy hemarthrosis haemophilia A in vivo imaging micro-CT

Reverse polarity shoulder replacement: Current concepts and review of literature

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2014年第3期5卷 255-261页

作者： Ling Hong Lee Aravind Desai Specialist Registrar Trauma and OrthopaedicsNorthern DeaneryNewcastle Upon TyneNE12 8RFUnited Kingdom

Shoulder replacement in cuff tear arthropathy(CTA)is an unsolved *** poses a soft tissue deficiency in an arthritic glenohumeral joint which the anatomical total shoulder replacement and hemiarthroplasty cannot reliably provide stability,range of movement,function or satisfactory long term *** the past two decades since the introduction of the reverse shoulder replacement,the prosthesis has evolved and has shown promising *** is a partially constraint joint by virtue of its design *** reversal of the concavity and convexity of the joint to the proximal humerus and the glenoid,respectively,also shifts and improves its center of rotation onto the osseous surface of the glenoid with less exposure to shear *** is a successful pain relieving procedure,offering good outcome in patients with irreparable massive rotator cuff tear with or without ***,this has led to wider use and expansion of its indication to include more complex elective and trauma *** originally used in the more elderly patients,there is increasingly more demand in the younger *** is important to have good quality long term data to support these increasing ***,we review the literature on the concepts of reverseshoulder replacement and the contemporary evidence.

关键词： Reverse shoulder replacement Biomechanic Cuff tear arthropathy Shoulder arthritis Proximal humerus fracture Review

Outcomes of gout in patients with cirrhosis:A national inpatient sample-based study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2023年第2期15卷 303-310页

作者： Ayham Khrais Aaron Kahlam Ali Tahir Amjad Shaikh Sushil Ahlawat Division of Medicine Rutgers New Jersey Medical SchoolNewarkNJ 07103United States Division of Medicine St.Luke’s University Health NetworkBethlehemPA 18015United States Division of Gastroenterology and Hepatology Rutgers New Jersey Medical SchoolNewarkNJ 07103United States

BACKGROUND Hyperuricemia is a prerequisite for the development of *** serum uric acid(UA)levels result from either overproduction or decreased excretion.A positive correlation between serum UA levels,cirrhosis-related complications and the incidence of nonalcoholic fatty liver disease has been established,but it is unknown whether hyperuricemia results in worsening cirrhosis *** hypothesize that patients with cirrhosis will have poorer gout *** To explore the link between cirrhosis and the incidence of gout-related *** This was a cross-sectional *** national inpatient sample was used to identify patients hospitalized with gout,stratified based on a history of cirrhosis,from 2001 to 2013 via the International Classification of Diseases,Ninth Revision,Clinical Modification *** outcomes were mortality,gout complications and joint ***χ^(2)test and independent t-test were performed to assess categorical and continuous data,*** logistic regression was used to control for confounding *** Patients without cirrhosis were older(70.37±13.53 years vs 66.21±12.325 years;P<0.05).Most patients were male(74.63%in the cirrhosis group vs 66.83%;adjusted P<0.05).Patients with cirrhosis had greater rates of mortality(5.49%vs 2.03%;adjusted P<0.05),gout flare(2.89%vs 2.77%;adjusted P<0.05)and tophi(0.97%vs 0.75%;adjusted P=0.677).Patients without cirrhosis had higher rates of arthrocentesis(2.45%vs 2.21%;adjusted P<0.05)and joint injections(0.72%vs 0.52%;adjusted P<0.05).CONCLUSION Gout complications were more common in *** without cirrhosis had higher rates of interventions,possibly due to hesitancy with performing these interventions given the higher complication risk in cirrhosis.

关键词： Gout Cirrhosis Hyperuricemia Uric acid Nonalcoholic fatty liver disease arthropathy

Minimally Invasive Hind-Foot Fusion in Charcot Patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Orthopedics 2023年第11期13卷 477-484页

作者： Sami Nogdallah Mohanad Osman Ibrahim Abd-Elseed Alaa Mohamed Mohamed Khairy Osama Gamal Nubi Montaser Fatooh Hozifa Mohammed Ali Abd-Elmaged Department of Orthopedics Alneelain University Khartoum Sudan Department of Orthopedics Orthopaedic Registrar Sudan Medical Specialization Board Khartoum Sudan Department of Orthopedics Bashaer University Hospital MBBS Al Neelan University Khartoum Sudan Department of Orthopedics Alzaiem Alazhari University Khartoum Sudan

Background: Hindfoot fusion, is a fusion of the talonavicular, talocalcaneal, and calcaneocuboid joints and is commonly performed for patients complaining of pain, chronic instability and gross deformity as a result of hindfoot pathology. Objective: This study aimed to assess the functional outcomes of the patients underwent hindfoot fusion, the post-operative complications and patient’s satisfaction. Methodology: This study is a prospective cohort study was conducted in Future hospital, in Khartoum, Sudan. It involved 30 patients from July 2015-July 2022. Data was collected by the primary researcher using data collection sheet, then it was cleaned and entered into Microsoft excel data sheet and was analysed using SPSS version 28 software. Results: 33.3% of the patients are aged 51 - 60 years, and >60 years. Male: Female equals 1:1. 56.7% are for the left side, only 23.3% developed complications. 63.3% patients are fully satisfied. There is a significant correlation between the AOFAS score before and after the operation. Also, a significant correlation between the means of AOFAS score after with the complications and the satisfaction of the patients. Conclusion: Minimally invasive tibio-talo-calcaneal is an alternative procedure for the treatment of severe Charcot arthropathy of the ankle. The expected functional outcome is impressive and comparable with the open surgery. However, the post-operative complications are prevalent in 23.3% of patients. Most candidates are fully satisfied with the procedure.

关键词： Ankle Sudan Patient Satisfaction arthropathy Neurogenic