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Antibacterial Effects of Ethanolic Extract of Zehneria scabra on Quails Artificially Infected with Salmonella Enteritidis

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Journal of Pharmacy and Pharmacology 2021年第11期9卷 387-396页

作者： Herman M.F Biekop Marc K Kouam Vivian Yengeh Gabriel T Kamsu Bridget Katte Alexis Teguia Biekop Herman Department of Animal Science Faculty of Agronomy and Agricultural SciencesPO BOX 188DschangCameroon Center for Research on Filariases and other Tropical Diseases(CRFilMT) P.O.Box 5797YaoundéCameroon Microbiology and Antimicrobial Substances Research Unit Faculty of ScienceUniversity of DschangCameroon 不详

Antimicrobial use in livestock is faced with various challenges including emergence of antimicrobial resistance and presence of drug residues in meat products,hence the need for *** aim of this work was to assess the effect a plant(Zehneria scabra)extract on Salmonella infected quails,as an alternative to antibiotic *** were randomly assigned into six groups each containing twelve *** neutral control(T0)group was not infected and received tap water whereas other groups were *** negative control(T-)received tap *** positive control(T+)received a single dose of oxytetracycline(20 mg/kg).T1,T2 andT3 orally received the plant extract at the following respective doses:9,18 and 37 mg/*** were infected by oral administration of a single dose of Salmonella Enteritidis(10^(5)CFU).Haematological and biochemical parameters were *** day 2 to day 9 to day 16,the bacterial load of all treatment groups(T+,T1,T2,T3)*** infection resulted in a significant(p<0.05)increase in serum levels of alanine aminotransferase,triglycerides,total cholesterol and white blood cells,and a significant decrease in the liver and kidney protein *** treatment resulted in the correction of the aforementioned *** plant extract(18 mg/kg)is as effective as oxytetracycline,and can be safely used in phytomedicine for the treatment of Salmonella Enteritidis infection without kidney and liver damage.

关键词： Zehneria scabra Salmonella Enteritidis antisalmonellal activity quails

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