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A New antimicrobial Flavonol Glycoside from Alchornea davidii

Chinese Chemical Letters 2003年第2期14卷 179-180页

作者： Gui You CUI Jun Yan LIU Ren Xiang TAN Institute of Functional Biomolecules School of Life SciencesNanjing UniversityNanjing 210093

A new flavonol glycoside, isorhamnetin-3-O-b-D-xyloside, was isolated from the extract of leaves and twigs of Alchornea davidii (Euphorbiaceae). Its structure was established on the basis of the spectral analysis and chemical degradation. antimicrobial assay showed that it moderately inhibited the growth of test bacteria (Staphylococcus aureus, Bacillus subtilis and Pseudomonas fluorescens) and fungi (Candida albicans, Aspergillus niger and Trichophyton rubrum) with MICs at 50 g/mL.

关键词： Alchornea davidii Euphorbiaceae flavonol glycoside antimicrobial activity.

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Optical Density and antimicrobial Characteristics of Georgian Propolis

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Journal of Pharmacy and Pharmacology 2016年第3期4卷 146-150页

作者： Ketevani Gabunia Department of Dentistry and Pharmacy Akaki Tsereteli State University 59 Tamar Mepe Street Kutaisi 4600 Georgia

Apiotherapy has been applied by Georgian people since time immemorial. Treatment with bee products in Georgia has been described in popular writings. Among bee products, honey and propolis are of most particular interest. Propolis is characterized by antimicrobial, antiviral, antioxidant, anticarcinogenic and analgesic properties. We have studied relationship between optical density and antimicrobial properties. Almost all samples of Georgian propolis are characterized by high optical density and antimicrobial activity. Studies have discovered that optical density was high in the samples of spring season. The maximal absorption values have been observed at a wavelength of 290-310 nm that is characteristic of flavonoids. Also, the sample with a relatively low optical density （Baghdati district） has exhibited antimicrobial activity.that is conditioned not by polyphenols, but flavonoids.

关键词： Propolis flavonoids flavonones optical density antimicrobial activity.

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