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Clinical features of ankylosing spondylitis associated with acute anterior uveitis in Chinese patients

International Journal of Ophthalmology(English edition) 2012年第2期5卷 164-166页

作者： Shu-Xing Ji, Huan Zou Daping Eye Hospital Institute of Surgery Research Daping Hospital Third Military Medical University Chongqing 400042 China Department of Ophthalmology 305 Hospital of Chinese PLA Beijing 100017 China

AIM: To characterize the clinical features, diagnosis, treatment and prognosis of uveitis associated with ankylosing spondylitis (AS) in Chinese patients. METHODS: Two hundred and three patients with uveitis associated with AS followed-up in the Third Military Medical University Daping Hospital between 2005 and 2010 were retrospectively evaluated in this study. Complete ophthalmological examinations were evaluated at baseline and during the follow-up period. The gender, age, follow-up time, mean frequency of uveitis onset, and accompanying eye examination findings, history, demographical parameters were reviewed. All the patients presented complete clinical and radiologic (sacroiliac, lumbar, dorsal and cervical spine, knee, ankle, shoulder, hip, elbow) evaluation. HLA-B27 typing was also searched. RESULTS: There were 203 patients diagnosed with AS associated welt's. All showed sacroiliac X-ray changes indicative of AS. There were 184 male and 19 female patients. The average age of patients was 35 +/- 12 (range 18-50). Mean follow-up period was 2.4 years (1-5 years). Acute anterior wets was the most common type of uveitis in both genders. 121 eyes presented unilateral involvement (55.2%), and 92 eyes presented bilateral involvement (45.3%) with onset alternately. 22 eyes occurred hypopyon, 16 eyes were found anterior vitreous cells, 7 eyes were noted reactive macular edema or exudation, 29 eyes presented posterior synechiae of iris, and 14 eyes presented cataract, 9 eyes presented secondary glaucoma, 2 eyes presented bend corneal degeneration and 1 eyes presented atrophy of eyeball. At the final visit, uveitis was well controlled in most patients. CONCLUSION: AS associated with uveitis in Chinese patients mainly manifests as acute anterior uveitis. A combination of corticosteroids with other mydriasis agents is effective for most AS associated with uveitis patients. In general, the prognosis is good in these cases.

关键词： HLA-B27 anterior uveitis acute anterior uveitis ankylosing spondylitis associated uveitis HLA-B27 associated uveitis

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Ten Years of Epidemiological and Diagnostic Aspects of Non-Traumatic anterior uveitis at Campus Teaching Hospital of Lome-Togo

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Open Journal of Ophthalmology 2023年第3期13卷 280-287页

作者： Nidain Maneh Adakou Aimée Victoire Abaglo Bénédicte Marèbe Diatewa Kanfiaguin Boundja Yawa Ebeva Nagbe Mawuli Ayodele Komi Santos Kokou Vonor Kokou Messan Amedome Didier Koffi Ayena Ophthalmology Department University of Lome Lome Togo Ophthalmology Department Teaching Hospital (CHU) Campus Lome Togo Ophthalmology Department University of Kara Kara Togo

Background: uveitis is a serious disease which dangerous complications can jeopardize the visual prognosis. anterior uveitis (AU) is the inflammation of the anterior uvea which is composed of the iris and the ciliary body. The objective of the study was to identify the epidemiological and etiological determinants of non-traumatic anterior uveitis at the Campus Teaching Hospital of Lomé. Materials and methods: Retrospective cross-sectional study of the records of patients diagnosed with anterior uveitis (AU) without a notion of trauma in the ophthalmology department of CHU Campus of Lomé from January 1, 2010 to December 31, 2019 (10 years). Results: 141 cases of uveitis, representing a prevalence of 0.18%. Female predominance, with a sex ratio of 0.76. Mean age was 34.74 ± 13.20 years. Decreased visual acuity was the primary complaint (34.40%), followed by ocular pain (28%). Non-traumatic anterior uveitis was unilateral in 87.2% of cases. Retro-corneal precipitates were present in all patients. 61.60% of patients had Tyndall in the anterior chamber. The etiology of non-traumatic AU was undetermined in 76.80% of cases. Toxoplasmosis, tuberculosis and syphilis were the main etiologies found. Conclusion: Non-traumatic anterior uveitis is relatively rare but serious, often affecting young subjects. It is a pathology that engages eye health professionals, not only because of the difficulties involved in diagnosing the etiology, but also because of its progression which sometimes leads to blindness.

关键词： anterior uveitis Non-Traumatic Epidemiology Etiology Lome

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Inhibitory　Effects　of　Tetandrine　on　Experimental　anterior　uveitis　Rabbits

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The Journal of Biomedical Research 1994年第1期18卷 44-44页

作者： Xiaon, Jigao,et, al. ACTA ACADEMIAE MEDICINAE NANJING,1994,14 (2):142-145

anterior uveitis was induced by injection of lens protein into anterior chamber of rabbit *** (Tet) (50mg/kg ip) showed marked inhibition on this ocular inflammation, the total content of prostaglandin E in irises, and leukocyte *** pathological examination revealed that inflammation of irises in Tet group was lighter than that in control group. The antiinflammatory mechanism of Tet may be related to reduction of intracellular free calcium and inhibition of synthesis of inflmmatory factor.

关键词： tetrandrine anterior uveitis lens protein prostaglandin E rabbit

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Intralenticular metallic foreign body: a case report

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International Journal of Ophthalmology(English edition) 2011年第3期4卷 326-328页

作者： S C Reddy Department of Ophthalmology Faculty of MedicineUniversity of Malaya

A case of retained intralenticular iron piece with signs of mild anterior uveitis at the time of presentation is reported in a 45 year-old man. His vision improved with topical cycloplegics and corticosteroids. After six months, his vision deteriorated grossly due to cataract formation. He regained good vision following removal of foreign body, extracapsular extraction with posterior chamber intraocular lens implantation. This case highlights the conservative management of the condition till the patient develops cataract resulting in visual disability; and good visual recovery following cataract surgery with intraocular lens implantation.

关键词： intralenticular foreign body anterior uveitis traumatic cataract penetrating eye injury

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