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anisakiasis in Southeast Asia: A story of new tropical disease?

Asian Pacific Journal of Tropical Biomedicine 2016年第5期6卷 382-383页

作者： Somsri Wiwanitkit Viroj Wiwanitkit Wiwanitkit House Bangkhae Hainan Medical University Faculty of Medicine University of Nis Joseph Ayobabalola University Dr DY Patil Medical University

anisakiasis is an important worm infestation. It is seen in some non-tropical countries and becomes an important issue in coastal medicine. However, in the few recent years, there are some reports on occurrence of anisakiasis in tropical countries. In this specific short article,the authors review and present the situation of anisakiasis in Southeast Asia. It can be said that anisakiasis becomes a new focused interest in tropical coastal medicine at present.

关键词： anisakiasis Southeast Asia Infestation Tropical disease

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Natural products:Perspectives in the pharmacological treatment of gastrointestinal anisakiasis

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Asian Pacific Journal of Tropical Medicine 2015年第8期8卷 604-609页

作者： Valero A Romero MC Gómez-Mateos M Hierro I Navarro MC Department of Parasitology.Faculty of Pharmacy.University of Granada Department of Pharmacology.Faculty of Pharmacy.University of Granada

Objective: To evaluate the activity of different natural products against L3 larvae of Anisakis type I. Methods: Information on investigations into the activity of natural products against the L3 larvae of Anisakis simplex was collected from scientific journals, books, theses and reports via a library and electronic search(using Pubmed, Scopus, Medline, Web of Science and Science Direct). The search terms included: natural products, medicinal plants, essential oils, terpenic derivatives, Anisakis, antinematodal activity. Results: In the literature reviewed numerous papers were found concerning the in vitro and in vivo activity against Anisakis type I of various natural products(plant extracts, essential oils and their major components). Analysis of the results showed that in vitro tests the Melaleuca alternifolia essential oil and the ar-turmerone isolated from Curcuma longa displayed the greatest activity. In vivo, the most active compound was perillaldehyde, the main component of Perilla frutescens essential oil. Conclusions: This study shows that some natural products exhibited promising antianisakis properties.

关键词： Anisakis anisakiasis Natural products Essential oils Terpenic derivatives

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Gastric and enteric anisakiasis successfully treated with Gastrografin therapy: A case report

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World Journal of Gastrointestinal Endoscopy 2018年第3期10卷 69-73页

作者： Hiroki Fujikawa Toshio Kuwai Toshiki Yamaguchi Ryoichi Miura Yuki Sumida Takeshi Takasago Yuki Miyasako Tomoyuki Nishimura Sumio Iio Hiroki Imagawa Atsushi Yamaguchi Hirotaka Kouno Hiroshi Kohno Department of Gastroenterology National Hospital OrganizationKure Medical Center and Chugoku Cancer Center

We report a case of a 59-year-old woman who was diagnosed with gastric and small intestinal anisakiasis, which was successfully treated with endoscopic extraction and Gastrografin therapy. She was admitted to our hospital with epigastric pain and vomiting one day after eating raw fish. She exhibited tenderness in the epigastrium without obvious rebound tenderness or guarding. Computed tomography (CT) demonstrated segmental edema of the intestinal wall with proximal dilatation and a small number of ascites. Because enteric anisakiasis was suspected based on the patient's history of recent raw fish consumption and abdominal CT, we performed gastroscopy and confirmed that nine Anisakis larvae were attached to the gastric mucosa. All of the Anisakis larvae were extracted via endoscopy, and the patient was diagnosed with gastric and enteric anisakiasis. Additionally, in the hospital, we performed ileography twice using Gastrografin, which led to shortened hospital stay. Based on the clinical results of this case, we suggest that Gastrografin therapy is a safe, convenient, and useful method to extract enteric Anisakis larvae.

关键词： Enteric anisakiasis Gastrografin Ileus Endoscopic extraction Anisakis larvae

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Asymptomatic anisakiasis of the Colon Diagnosed and Treated by Colonoscopy

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Case Reports in Clinical Medicine 2020年第9期9卷 288-294页

作者： Tomoshi Takeda Kenji Niwa Akie Sano Atsunori Kodama Kuninori Hatasa Yasunari Matsuno Masao Kagami Motoki Takenaka Kohjiro Niwa Takuji Tanaka Department of Internal Medicine Gujo City Hospital Shimadani Gujo City Gifu Japan Section of Laboratory Medicine and Obstetrics & Gynecology Gujo City Hospital Shimadani Gujo City Gifu Japan Sano Internal Medicine Clinic Naka-fukuno-cho Seki City Gifu Japan Department of Obstetrics & Gynecology Gifu University School of Medicine Yanagido Gifu City Japan Department of Internal Medicine Kizawa Memorial Hospital Shimokobi Kobicho Minokamo City Japan Department of Diagnostic Pathology & Research Center of Diagnostic Pathology Gifu Municipal Hospital Gifu City Japan

anisakiasis can involve any part of the digestive tract, but most cases reported have involved the stomach;few reports have described colonic anisakiasis. Furthermore, asymptomatic colonic anisakiasis has been reported to be very rare. A 58-year-old Japanese male asymptomatically received colonoscopy due to a fecal occult blood testing positive, and an Anisakis larva was removed in the ascending colon. After colonoscopy, an detailed questionings concerning eating raw fish revealed that the patient ate the liver of raw filefish 21 days before the colonoscopy. Thus, questionings concerning eating the raw fish were very important and helpful for correct diagnosis. This case report demonstrated that colonic anisakiasis can be diagnosed by colonoscopy before severe complications (intestinal obstruction, perforation, and cancer development) occur. Also, biopsy forceps could be used to remove the Anisakis worms, demonstrating that diagnosis and treatment can be simultaneously performed.

关键词： Asymptomatic anisakiasis Ascending Colon Colonoscopy Risk Factor for Cancer

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