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Categorization and Frequency of Indications for Packed Cell Transfusion in the Preterm Newborn during the Initial Hospital Stay at a Tertiary Care Hospital: A Cross-Sectional Study

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Open Journal of Pediatrics 2021年第4期11卷 786-796页

作者： Shirin Surani Heeramani Lohana Sheraz Ahmed Rabia Hassan Sapna Kewalani Khalil Ahmed Aga Khan Maternal and Child Care Centre Hyderabad Pakistan

Introduction: Packed cell transfusion is a lifesaving procedure in premature babies as they have more complications as compared to babies who are born at term. Complications related to prematurity increase as gestational age decreases and anemia is one of the complications of prematurity which needs packed cell transfusions. To date, when to transfuse preterm babies and what would be the threshold for hemoglobin and hematocrit is still a point of argument as well as liberal versus restrictive transfusion protocols have been developed but what should be followed still needs more data. In our study, we have observed frequencies of different indications of packed cell transfusion in the neonatal intensive care unit of a tertiary care hospital. This endeavor will help in the establishment of guidelines regarding transfusion and the threshold on which any intervention should be done also it would be a step towards the identification of preventable causes that lead to transfusion and transfusion-related risks and hazards. Objective: To determine the indication of packed cell transfusion and their frequencies in preterm neonates. Study Design: This was a cross-sectional study. Setting: The study was carried out in the neonatal intensive care unit (NICU). Study Duration:

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早产儿支气管肺发育不良和红细胞输注间的关系(英文)

早产儿支气管肺发育不良和红细胞输注间的关系(英文)

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2014年浙江省医学会儿科学分会学术年会暨儿内科疾病诊治新进展国家级继续教育学习班

作者：张志群 Xian-Mei HUANG Hui LU Division of Neonatology Department of PediatricsHangzhou First People's Hospital Department of Pediatrics Hangzhou First People's Hospital

Background:anemia of prematurity(AOP) and transfusion of packed red blood cells(PRBCs) are both common in preterm *** transfusion is used for the treatment of AOP to increase the oxygen carrying capacity of *** transfusion has been shown to result in higher rates of organ ***:To determine whether PRBC transfusion for AOP was associated with an incidence of bronchopulmonary dysplasia(BPD) in *** Design:This retrospective study was performed on all live-born neonates with birth weights ≤ 1,500 g or gestational age(GA) ≤ 32 weeks admitted from 2008 to *** who received PRBC transfusion and those who did not receive PRBC transfusion were compared for incidence of BPD and other ***:Of 209 patients,119 received PRBC transfusion before diagnosed BPD(group 1) and 90 did not receive PRBC or PRBC transfusion after diagnosed BPD(group 2).The incidence of BPD was higher in group 1 than group 2(37.8 vs.2.2%,p < 0.00001);after adjusting for significant risk factors,the adjusted odds ratio for BPD was 9.541(95% CI 2.031,44.806),p = ***:This study shows an association between PRBC transfusion and increased incidence of BPD in preterm infants.

关键词： prematurity bronchopulmonary dysplasia transfusion red blood cells anemia of prematurity

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