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MICROSTRIP APPLICATOR FOR TREATMENT OF CERVICAL EROSION AND CERVICAL CONDYLOMA acuminatum

Chinese Journal of Biomedical Engineering(English Edition) 1998年第2期7卷 87-92页

作者： Xiangyue Sha Zukui Song Xiaobin Ye Qin Xi(Department of Electronic Science and EngineeringDepartment of PhysicsNanjing University, Nanjing 210093, China)Zhixue You Weizhang Tang(Department of Gynecology and ObstetricsJiangsu Province Hospital, Nanjin

This Paper introduces a microstrip applicator for treatment of cervical erosion and cervical condyloma acuminatum with microwave tissue coagulationmethod. The principle of the applicator,the theoretical calculation of near field distribution of the applicator covered with a lossy dielectric, the experimental resultsfor its performance of the impedance matching and for microwave leakage energyare reported. Finally,the therapeutic method and effects are presented.

关键词： microstrip applicator cervical erosion cervical condyloma acuminatum safe effect

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A　comparative　study　on　the　angiogenic　activity　of　condyloma　acuminatum　and　basal　cell　carcinoma

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Journal of Medical Colleges of PLA(China) 1996年第1期11卷 52-56页

作者：曾抗王瑞善王鸿涛吴让科唐跃斌谭仲楷黄卓垣

Recently, the study on the extraction, component analysis and function of angiogenic factor (AF) has become an important subject in anti-tumor research and made a great progress. Therefore, the imitation of the tumor's angiogenic activity (AGA) possibly helps to find a new method to treat ischemic diseases by blood vessel proliferation. Most of the parenchymatous malignant tumors have AGA. We studied the early stage condyloma acuminatum (CA) . After transplanting CA onto the chorioallantoic membrane (CAM) of chick embryos, we observed the AGA of CA and carefully compared it with that of basal cell carcinoma which is generally considered to have strong AGA. Meanwhile, we explored the way by which the AF of CA comes into being. The results demonstrated that CA, a benign neoplastic lesion, at its early stage, also has AGA. It is postulated that the responsible material is a certain form of AF. Therefore, the study on AGA of benign lesions (such as CA) and its physical basis will have potential clinical significance.

关键词： condyloma acuminatum angiogenic factor angiogenic activity chorioallantoic membrane basal cellcarclnoma

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Successful treatment of giant condyloma acuminatum with 5-aminolevulinic acid-photodynamic therapy

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International Journal of Dermatology and Venereology 2018年第4期1卷 235-236页

作者： Li-Li Zhang Chen Huang Department of Dermatology the First People's Hospital of Huainan Huainan Anhui 232007 China Department of Dermatology Peking University First Hospital Beijing 100034 China

Introduction Giant condyloma acuminatum, which is also known as Buschke-Loewenstein tumor (BLT), is a uncommon sexually-transmitted disease affecting the genitals and characterized by a slow and locally-invasive growth pattern. It was first reported in 1925[1], and was defined as'carcinoma-like condylomata acuminate of the penis'by Loewenstein in 1938(2)The typical clinical manifestations included exophytic, fungating masses, sometimes with a cauliflower-like morpho-logy. Therapies including surgical excision are effec-tive to the lesions of giant condyloma acuminatum, but the high recurrence rate brings troubles and pain to patients. In this report, we used electrosurgery and carbon dioxide (CO2) laser as the primary treatment followed by 5-aminolevulinic acid-photodynamic therapy (5-ALA PDT), and achieved 100% clinical efficacy on a case of giant condyloma acuminatum.

关键词： Giant condyloma acuminatum Buschke-Loewenstein tumor

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The Efficacy of Podophyllin Cautery Added to Surgical Excision for Eradication of Vulvar Condylomata Accuminata;Randomized Controlled Trial

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Journal of Cancer Therapy 2018年第7期9卷 559-567页

作者： Hussein O. Soliman Yossra Lashin Department of Surgical Oncology National Cancer Institute Cairo University Giza Egypt Department of Gynecology and Obstetrics Faculty of Medicine Cairo University Giza Egypt

Context: Condyloma acuminatum is a common morbidity caused by human papillomavirus infection. Objective: To compare the recurrence rate after surgical excision with or without podophyllin cautery. Design, Setting, Participants: Sixty women were enrolled in a study that was conducted in Cairo from Jan-2017 to Mar-2018. Interventions: All women received the same preparations. After randomization;in the study group (N = 30), podophyllin cautery was added to surgical removal in the follow-up period. In the control group (N = 30), only surgical removal was used. Main Outcome Measure: The main outcome measure was the estimation of the recurrence of the lesion during the follow-up period. The secondary outcome measures were the incidence of adverse events. Results: Both groups were comparable (p-value > 0.05) with regard to the age and BMI. Recurrence was significantly lower (P = 0.001) in the study group than the control group. In the study group, five cases (17.2%) have recurrence whereas, in the control group, 18 (60.0%) had suffered recurrence. The ARR was 42.8% (CI 95%: 18% - 60.9%) with RR of 0.29 (CI 95%: 0.12% - 0.67%) and NNT2 (CI 95%: 6% - 2%). During the follow-up period, 19 cases (65.5%) of the study group experienced pain versus only eight cases (26.7%) in the control group (p = 0.003). However, the development of scars was less in the study group 7 (24.1%) than in the control group 19 (63.3%), (p = 0.002). Conclusion: Podophyllin cautery, when added to surgical removal, is effective in decreasing the incidence recurrence in cases with condylomata acuminata.

关键词： Condyloma acuminatum Recurrence Adverse Events Podophyllin Cautery Surgical Excision

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