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actigraphy: A new diagnostic tool for hepatic encephaiopathy

World Journal of Gastroenterology 2006年第14期12卷 2243-2244页

作者： Isabelle Hourmand-Ollivier Marie-Astrid Piquet Jean Pierre Toudic Pierre Denise Thng Dao Department of Nutrition and Hepatogastroenterology CHU Cte de Nacre-14033 cedex Caen France Physiology Laboratory CHU Cte de Nacre-14033 cedex Caen France

AIM： To assess the actigraphy, an ambulatory and continuous monitoring of wrist motor activity fitted to study sleep/wake patterns in hepatic encephalopathy （HE）. METHODS： Twenty-five cirrhotic patients （17 M, 8 F, mean age 56± 11 years, 24/25 alcoholic, Child-Pugh A, B, C： 2, 6, 17） were included. The patients were classified into 3 groups： stage 0 group （n = 12）, stage 1-2 group （n = 6）, and stage 3-4 group （n = 7） of encephalopathy. Over three consecutive days, patients had clinical evaluation 3 times a day with psychometric test, venous ammoniemia, flash visually evoked potentials （VEP）, electroencephalogram and continuous actigraphic monitoring for 3 d, providing 5 parameters： mesor, amplitude, acrophase, mean duration of activity （MDAI） and inactivity （MDII） intervals. RESULTS： Serum ammonia and VEP did not differ among the 3 groups. Electroencephalography mean dominant frequency （MDF） correlated significantly with clinical stages of HE （r=0.65, P=0.003）. The best correlation with HE stage was provided by actigraphy especially with MDAI （r= 0.7, P〈10^-4） and mesor （r= 0.65, P〈 10^-4）. MDAI correlated significantly with MDF （r= 0.62, 0.004） and was significantly shorter in case of HE compared to patients without HE （stage 0： 5.33± 1.6 min; stage 1-2：3.28±1.4 min; stage 3-4：2.52±1.1 min; P〈0.05）. Using a threshold of MDAI of less than 4.9 min, sensitivity, specificity, positive predictive value, negative predictive value for HE diagnosis were 85%, 67%, 73% and 80%, respectively. CONCLUSION： actigraphy may be an objective method to identify HE, especially for early HE detection. Motor activity at the wrist correlates well with clinical stages of HE. MDAI and mesor are the most relevant parameters.

关键词： Hepatic encephalopathy Cirrhosis actigraphy

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Practice parameters for the use of actigraphy in the military operational context: the Walter Reed Army Institute of Research Operational Research Kit-actigraphy(WORK-A)

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Military Medical Research 2021年第1期8卷 103-115页

作者： Jaime K.Devine Jake Choynowski Tina Burke Kajsa Carlsson Vincent F.Capaldi Ashlee B.McKeon Walter J.Sowden Operational Fatigue and Performance Institutes for Behavior ResourcesBaltimoreMD 21218USA Behavioral Biology Branch Walter Reed Army Institute of Research503 Robert Grant AveSilver SpringMD 20910USA Tripler Army Medical Center HonoluluHI 96859USA

Background: The Walter Reed Army Institute of Research(WRAIR) Operational Research Kit-actigraphy(WORK-A) is a set of unique practice parameters and actigraphy-derived measures for the analysis of operational military sleep patterns. The WORK-A draws on best practices from the literature and comprises 15 additional descriptive variables. Here, we demonstrate the WORK-A with a sample of United States Army Reserve Officers’ Training Corps(ROTC) cadets(n=286) during a month-long capstone pre-commissioning training ***: The sleep of ROTC cadets(n=286) was measured by Philips Actiwatch devices during the 31-day training exercise. The preliminary effectiveness of the WORK-A was tested by comparing differences in sleep measures collected by Actiwatches as calculated by Philips Actiware software against WORK-A-determined sleep measures and self-report sleep collected from a subset of ROTC cadets(n=140).Results: Actiware sleep summary statistics were significantly different from WORK-A measures and self-report sleep(P≤0.001). Bedtimes and waketimes as determined by WORK-A major sleep intervals showed the best agreement with self-report bedtime(22:21±1:30 vs. 22:13±0:40, P=0.21) and waketime(04:30±2:17 vs. 04:31±0:47, P=0.68). Though still significantly different, the discrepancy was smaller between the WORK-A measure of time in bed(TIB) for major sleep intervals(352±29) min and self-report nightly sleep duration [(337±57) min, P=0.006] than that between the WORK-A major TIB and Actiware TIB [(177±42) min, P≤0.001].Conclusions: Default actigraphy methods are not the most accurate methods for characterizing soldier sleep, but reliable methods for characterizing operational sleep patterns is a necessary first step in developing strategies to improve soldier readiness. The WORK-A addresses this knowledge gap by providing practice parameters and a robust variety of measures with which to profile sleep behavior in service members.

关键词： actigraphy Sleep-wake patterns Military sleep assessment Operational environment Scoring methodology

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SOOJI CHIM (Koryo hand acupuncture) for perimenopausal insomnia:Evidence from actigraphy and serum hormone testing

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World Journal of Acupuncture-Moxibustion 2019年第4期29卷 274-278页

作者： Fei-Yi Zhao Jin-Hyeok Kim Li-Ping Yue Hai-Xia Yan Hua-Ling Song Yan Xu Hong Xu Yu-Fang Hong Qiang-Qiang Fu Nursing Department Shanghai SANDA UniversityShanghai 201209China Shanghai University of Traditional Chinese Medicine Shanghai 201203China Shanghai Municipal Hospital of TCM Affiliated to Shanghai TCM University Shanghai 200071China Research Department Yangpu HospitalTongji UniversityShanghai 200090China

Objective:This study is conducted to determine the effects of SOOJI CHIM(Koryo hand acupuncture,KHA)therapy on sleep structures and perimenopause symptoms among ***:Totally 49 participants who met the inclusion criteria were enrolled in a two-arm randomized,placebo controlled,patients-blind trial,with 24 cases allocated to a real-KHA group and 25 cases allocated to a sham-KHA *** in each group received corresponding treatment every other day,three times a week for total eight *** actigraphy and testing of serum hormones level reflected by biological markers such as follicle-stimulating hormone(FSH),luteinizing hormone(LH)and estradiol(E2)were performed at pre-and ***,the scores of Pittsburgh sleep quality index(PSQI)was used for assessing the subjective sleep experience of ***,adverse effects were monitored and ***:After eight-week treatment,the global scores of PSQI declined significantly(P0.05).According to the outcomes of actigraphy,a striking increase was observed in both sleep efficiency(SE)and total sleep time(TST)in the real-KHA group(both P0.05).However,no significant changes of sleep awakenings(SA)in both groups was found after treatment(both P>0.05).Meanwhile,FSH and LH in the real-KHA group decreased markedly after intervention(both P0.05).The fluctuation of E2 levels were not significant in both groups(both P>0.05).No serious adverse event was reported in either real-or sham-KHA ***:KHA may be a potential alternative therapy for improving perimenopausal insomnia via down regulating the levels of FSH and LH.

关键词： Perimenopausal insomnia SOOJI CHIM(Koryo hand acupuncture,KHA) actigraphy Serum hormone testing

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Sleep Posture Affects Sleep Parameters Differently in Young and Senior Japanese as Assessed by actigraphy

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Health 2014年第21期6卷 2934-2944页

作者： Akiko Nojiri Chikako Okumura Yushi Ito Faculty of Rehabilitation Kumamoto Health Science University Kumamoto Japan Division of Brain Sciences Department of Physiology Faculty of Medicine Kurume University School of Medicine Kurume Japan

In an attempt to study the relationship between sleep postures and sleep parameters assessed by actigraphy, we applied the newly developed Activity Monitoring and Evaluation System (A-MES) and actigraphy at the same time to younger and senior Japanese volunteer groups. It was found that sleep postures and diurnal activity determines, to some extent, sleep parameters including activity mean score (AMS), activity index (ACTX), waking episodes (WEP) and sleep fragmentation index (SFX). It was also found that sleep properties are different in younger and senior Japanese. For example, increase in the proportion of time in the supine position resulted in enhancement and deterioration of the sleep in the younger and senior groups, respectively. Furthermore, there were correlations between supine posture and AMS, ACTX, SFX, total minutes scored as awake (TMSA) and WEP obtained by actigraphy in the younger group, but only AMS and ACTX in senior group. In addition, we also assessed sleep parameters by use of questionnaires, and found that objective sleep quality was rather poor but subjective sleep quality was better in the senior group. In the younger group, in contrast, objective sleep quality was better but subjective sleep quality was poor. On the other hand, there was no correlation between sleep parameters assessed by actigraphy and self-report at all. The present study with A-MES and actigraphy provides the first evidence that sleep posture affects sleep quality and is a convenient, inexpensive and home-based method for studying sleep.

关键词： actigraphy Activity Monitoring and Evaluation System (A-MES) Sleep Posture Sleep Quality Good Sleepers

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Ambulatory clinical parameters and sleep respiratory events in a group of obese children unselected for respiratory problems

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World Journal of Pediatrics 2017年第6期13卷 577-583页

作者： Marco Zaffanello Giorgio Piacentini Angelo Pietrobelli Cristiano Fava Giuseppe Lippi Claudio Maffeis Emma Gasperi Luana Nosetti Sara Bonafini Angela Tagetti Franco Antoniazzi Department of Surgical Sciences DentistryGynecology and PediatricsPediatric Division Department of Medicine Section of General Medicine and Hypertension Department of Neuroscience Biomedicine and MovementChemistry and Clinical Microscopy Section University of VeronaVeronaItaly Pediatric Diabetes and Metabolic Disorders Unit Department of Pediatrics University of InsubriaVareseItaly

Background:Obstructive sleep apnea in children is frequently due to tonsil and adenoid *** study aimed to investigate the relationship between ambulatory clinical parameters and sleep respiratory events in obese ***:We carried out a prospective respiratory sleep study between 2013 and *** obstruction,tonsils enlargement and palate position were subjectively *** attention deficit hyperactivity disorder (ADHD) rating scale for parents was also *** polygraph study was performed using a portable ambulatory ***:Forty-four obese children were consecutively recruited into this *** sleep respiratory disturbance was showed in 31.8 % of patients;18.2% previously had an adeno (tonsillectomy).In 50% of these obese children,both apnea-hypopnea index and oxygen desaturation index showed polygraph abnormal *** rating scale for parents scores were positive in 9.1% of ***:We found a high rate of mild sleep respiratory disturbance and ADHD-like symptoms referred by *** respiratory disturbance was not totally cured by ***,otorhinolaryngology variables were not able to explain mild sleep respiratory disturbance.

关键词： actigraphy obesity obstructive sleep apnea upper respiratory tract obstruction

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Acupuncture treatment of a male patient suffering from long-term schizophrenia and sleep disorders

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Journal of Traditional Chinese Medicine 2017年第6期37卷 862-867页

作者： Peggy Bosch Heike Staudte Sujung Yeo Sook-Hyun Lee Sabina Lim Maurits van den Noort Donders Centre for Cognition Radboud University NijmegenNijmegen 6525 HRThe Netherlands Psychiatric Research Institute LVR-Klinik Bedburg-HauBed-burg-Hau 47551Germany Psychiatric Research Institute LVR-Klinik Bedburg-HauBedburg-Hau 47551Germany Department of Acupuncture&Meridian of Oriental Medicine Sang Ji UniversityWonju 26339Republic ofKorea Research Group of Pain and Neuroscience Kyung Hee UniversitySeoul 130-701Republic of Korea Research Group of Pain and Neuro-science Kyung Hee UniversitySeoul 130-701Republic of Korea.Brussels Institute for Applied LinguisticsFree Univer-sity of BrusselsBrussels 1050Belgium

OBJECTIVE: To investigate the effectiveness of acupuncture in the treatment of chronic schizophrenia and co-morbid sleep ***: A 42-year-old German male outpatient,suffering from long-term schizophrenia and sleep disorders, entered the study. Acupuncture was used as a non-pharmacological intervention. In addition to his ongoing Western Medicine(pharmacological) treatment, the patient received 12 weekly(non-standardized) acupuncture treatments in the clinic. The Traditional Chinese Medicine(TCM) diagnosis, the psychological assessment and the actiwatch data were compared before and after the acupuncture ***: The TCM diagnosis revealed a Liver Fire pattern before the acupuncture treatment, which was still present, although to a lesser degree, after the treatment. The psychological assessment revealed no change in the positive symptoms, but a small decrease in the negative symptoms and the general psychopathology of the patient. This was further illustrated by the small decrease in the number of depressive symptoms. The subjective sleep disorders improved markedly after acupuncture treatment, but the daytime sleepiness did not. The actiwatch results showed that after acupuncture treatment, the patient was moving less during sleep, but no significant results were found for the other sleep ***: Acupuncture was found to be an effective non-pharmacological add-on method for treating subjective sleep disorders, and, to a lesser degree, objective sleep disorders and the negative symptoms of chronic schizophrenia. Future larger clinical trials with follow-up measurements are needed in order to replicate the present preliminary beneficial acupuncture findings and in order to determine whether the observed effects can be sustained.

关键词： actigraphy Acupuncture Schizophre-nia Sleep weak disorders

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Deconstructing athletes’sleep:A systematic review of the influence of age,sex,athletic expertise,sport type,and season on sleep characteristics

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Journal of Sport and Health Science 2021年第4期10卷 387-402页

作者： Angelos Vlahoyiannis George Aphamis Gregory C.Bogdanis Giorgos K.Sakkas Eleni Andreou Christoforos D.Giannaki Department of Life and Health Sciences University of NicosiaNicosia 1700Cyprus School of Physical Education and Sport Science National and Kapodistrian University of AthensAthens 17237Greece Department of Physical Education and Sport Science University of ThessalyTrikala 42100Greece School of Sport and Health Sciences Cardiff Metropolitan UniversityCardiff CF52YBUK

Purpose:This systematic review aimed to describe objective sleep parameters for athletes under different conditions and address potential sleep issues in this specific ***:PubMed and Scopus were searched from inception to April *** studies measured sleep only via objective evaluation tools such as polysomnography or *** modified version of the Newcastle-Ottawa Scale was used for the quality assessment of the ***:Eighty-one studies were included,of which 56 were classified as medium quality,5 studies as low quality,and 20 studies as high quality.A total of 1830 athletes were monitored over 18,958 *** values for sleep-related parameters were calculated for all athletes according to sex,age,athletic expertise level,training season,and type of *** slept on average 7.2±1.1 h/night(mean±SD),with 86.3%±6.8%sleep efficiency(SE).In all datasets,the athletes’mean total sleep time was<8 *** was low for young athletes(80.3%±8.8%).Reduced SE was attributed to high wake after sleep onset rather than sleep onset *** heavy training periods,sleep duration and SE were on average 36 min and 0.8%less compared to pre-season and 42 min and 3.0%less compared to in-season training periods,***:Athletes’sleep duration was found to be short with low SE,in comparison to the general consensus for non-athlete healthy *** sleep issues were revealed in young *** quality and architecture tend to change across different training periods.

关键词： actigraphy Polysomnography Sleep architecture Sleep duration Sleep quality

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Sleep and stress in the acute phase of concussion in youth

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Sports Medicine and Health Science 2020年第2期2卷 109-114页

作者： Arthur Maerlender Caitlin Masterson Jessica L.Calvi Todd Caze Ross Mathiasen Dennis Molfese Center for Brain Biologyand BehaviorEast StadiumUniversity of Nebraska-LincolnNEUSA Nebraska Medicine S 42nd&Emile StOmahaNEUSA Salivary Bioscience Laboratory East StadiumUniversity of Nebraska-LincolnNEUSA University of Nebraska Medical School S 42nd&Emile StOmahaNEUSA

This study sought to address the complex interplay between both biological and psychological perceptions of stress and sleep in the acute stages following a mild traumatic brain injury.A secondary goal was to identify potential targets for *** acutely injured youth(mean age 12 years)were studied at home with overnight actigraphy,salivary cortisol and melatonin assays,and subjective ratings of stress and fatigue(injured group).Nine matched control youth also were assessed(control group).Results suggested longer sleep latencies(time to fall asleep)and higher levels of fatigue in the injured group exist(p=0.025 and p=0.004,respectively).In the injured group,stress and sleep onset were significantly related with most subjects meeting criteria for Acute Stress *** levels were lower at bedtime in the injured *** samples were collected via passive drool at three time points:~1 h before bed(“bedtime”or T1),immediately upon waking(time 2:T2),and 30 min post-waking(time 3:T3).Overnight increases in cortisol(T1 to T2)were greater for the injured group;however,post-sleep changes in cortisol(T2 to T3)were reversed with control concentrations *** findings are unique in using actigraphy and salivary hormone levels in an acutely injured youth while in their *** differences in sleep latency and the presence of injury-related stress point to potential treatment targets in acute concussion.

关键词： Sleep Mild traumatic brain injury Fatigue actigraphy Youth Salivary hormones Stress Concussion

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Sleep quality improved following a single session of moderate-intensity aerobic exercise in older women:Results from a pilot study

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Journal of Sport and Health Science 2014年第4期3卷 338-342页

作者： Xuewen Wang Shawn D.Youngstedt Department of Exercise Science University of South CarolinaColumbiaSC 29208.USA Division of Geriatrics and Nutritional Science Washington University School of MedicineSt.LouisMissouri 63110USA

Background： Poor sleep quality is associated with adverse effects on health outcomes. It is not clear whether exercise can improve sleep quality and whether intensity of exercise affects any of the effects. Methods： Fifteen healthy, non-obese （body mass index = 24.4 ± 2.1 kg/m^2, mean 4- SD）, sedentary （〈20 min of exercise on no more than 3 times/week） older women （66.1 ± 3.9 years） volunteered for the study. Peak oxygen consumption （VO2peak） was evaluated using a graded exercise test on a treadmill with a metabolic cart. Following a 7-day baseline period, each participant completed two exercise sessions （separated by 1 week） with equal caloric expenditure, but at different intensities （60% and 45% VO2peak, sequence randomized） between 9：00 and 11：00 am. A wrist ActiGraph monitor was used to assess sleep at baseline and two nights following each exercise session. Results： The average duration of the exercise was 54 and 72 rain, respectively at 60% （moderate-intensity） and 45% VO2peak （light-intensity）. Wake time after sleep onset was significantly shorter （p = 0.016）, the number of awakenings was less （p = 0.046）, and total activity counts were lower （p = 0.05） after the moderate-intensity exercise compared to baseline no-exercise condition. Conclusion： Our data showed that a single moderate-intensity aerobic exercise session improved sleep quality in older women.

关键词： actigraphy Activity counts Exercise Older adults Sleep quality Wake after sleep onset

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The relationship between sleep condition and autonomic nervous function in women in their 70s with type 2 diabetes mellitus

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Health 2013年第11期5卷 1875-1883页

作者： Miki Sato Yuko Yasuhara Tetsuya Tanioka Yukie Iwasa Masafumi Miyake Haruo Kobayashi Rozzano C. Locsin Seizo Kinoshita Masatoshi Masuda Hiroshi Shimizu Christine E. Lynn College of Nursing Florida Atlantic University Boca Raton USA Department of Nursing Faculty of Nursing Shikoku University Tokushima Japan Department of Nursing Institute of Health Biosciences The University of Tokushima Graduate School Tokushima Japan Faculty of Medical Welfare Kawasaki University of Medical Welfare Kurashiki Japan Kinoshita Hospital Tokushima Japan Tokushima Prefectural Minami Health Care Center Tokushima Japan Toyo Hospital Tokushima Japan

The aim of this study was to determine the relationship between sleep condition and autonomic nervous function of women in their 70s with type 2 diabetes mellitus by analyzing the activity counts (AC) on actigraphs and heart rate variability (HRV). Ten healthy women in their 30s to 40s as control and four women patients with type 2 diabetes in their 70s wore the electrocardiograph and an actigraph for 24 hours while keeping a diary of activities, including their sleep and food intake. The Pittsburgh Sleep Quality Index was used to assess subjective sleep conditions. The subjective sleeping results were significantly correlated with those measured by the AC and HRV. However, AC and HRV correlation pattern showed different activity in the patients with type 2 diabetes mellitus. The quality of sleep of those with chronic diabetes was not good even if their HbA1c was well controlled. Furthermore, their automatic nervous function was different from the control group. The sleeping hours of patients with type 2 diabetes were shorter or longer than those of healthy women. Ultimately, this study maintains that it is important to examine automatic nervous functions using objective examination index during the early stage of diabetes mellitus.

关键词： actigraphy Heart Rate Variability Autonomic Nervous Function Sleep Condition Diabetes HbAlc

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