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Advanced wasting in peritoneal dialysis patients

World Journal of Nephrology 2017年第3期6卷 143-149页

作者： Zhi Xu Glen H Murata Robert H Glew Yijuan Sun Darlene Vigil Karen S Servilla Antonios H Tzamaloukas Nephrology Division Department of MedicineUniversity of New Mexico School of Medicine Research Service Raymond G.Murphy Veterans Affairs Medical Center Department of Surgery University of New Mexico School of Medicine Renal Section Medicine ServiceRaymond G.Murphy VA Medical Center Department of Medicine University of New Mexico School of Medicine Research Service and Renal Section Raymond G.Murphy VA Medical Center

AIM To identify patients with end-stage renal disease treated by peritoneal dialysis(PD) who had zero body fat(BF) as determined by analysis of body composition using anthropometric formulas estimating body water(V) and to compare nutritional parameters between these patients and PD patients whose BF was above *** Body weight(W) consists of fat-free mass(FFM) *** formulas for calculating V allow the calculation of FFM as V/0.73,where 0.73 is the water fraction of FFM at normal *** from loss of BF has adverse survival outcomes in *** wasting was defined as zero BF when V/0.73 is equal to or exceeds *** study,which analyzed 439 PD patients at their first clearance study,used the watson formulas estimating V to identify patients with V_(watson)/0.73 ≥ W and compared their nutritional indices with those of PD patients with V_(watson)/0.73 watson)/0.73 ≥ W among 439 patients on *** to 260 other male patients on PD,the two subjects with advanced wasting had exceptionally low body mass index and serum albumin *** first of the two subjects also had very low values for serum creatinine concentration and total(in urine and spent peritoneal dialysate) creatinine excretion rate while the second subject had an elevated serum creatinine concentration and high creatinine excretion rate due,most probably,to non-compliance with the PD *** Advanced wasting(zero BF) in PD patients,identified by the anthropometric formulas that estimate V,while rare,is associated with indices of poor somatic and visceral nutrition.

关键词： Weight deficit Fat-free mass Nutrition Body water Anthropometry Peritoneal dialysis watson formulas Wasting

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